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Erschienen in: World Journal of Surgery 7/2018

30.12.2017 | Original Scientific Report

Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies

verfasst von: Hassen Hentati, Chady Salloum, Philippe Caillet, Eylon Lahat, Mara Disabato, Eric Levesque, Philippe Compagnon, Chetana Lim, Daniel Azoulay

Erschienen in: World Journal of Surgery | Ausgabe 7/2018

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Abstract

Background

Emergency digestive surgery is being increasingly performed in elderly patients. The aim of the present study was to identify the predictors of mortality and morbidity following emergency digestive surgery in patients aged 80 years and older.

Methods

A single-center retrospective review was performed of consecutive patients aged ≥65 years operated for a digestive surgical emergency between January 2011 and December 2013. Two groups were compared: group A (aged 65–79 years) and group B (aged ≥80 years).

Results

The study population included 185 patients: 76 patients in group A and 109 in group B. The mean age was 79.9 years (65–104 years). The overall 90-day mortality rate was 23.2 and 31.9% at 1 year, which was similar between groups. The overall morbidity was 28.6%. No differences were noted between the two groups in overall, minor (Dindo I–II) or major (Dindo III–IV) morbidity rates. Multivariate analysis identified pulmonary disease (odds ratio, OR = 6.43, p = 0.02), bowel ischemia (OR = 11.41, p = 0.01), postoperative ICU stay (OR = 7.37, p < 0.0001) and the occurrence of postoperative complications (OR = 2.66, p = 0.03) as predictors of 90-day mortality. Predictors of in-hospital morbidity were preoperative hemoglobin <12 g/dL (OR = 2.49, p = 0.02) and postoperative intensive care unit (ICU) stay (OR = 6.69, p < 0.0001). An age ≥80 year was not associated with mortality or morbidity in this study.

Conclusions

The decision to perform abdominal surgery in the emergency setting should be based on physiological status, which accounts for a patient’s comorbidities and health status, rather than on chronological age per se.
Literatur
1.
Zurück zum Zitat Katlic MR (2001) Principles of geriatric surgery. In: Rosenthal RA, Zenilman ME, Katlic MR (eds) Principles and practice of geriatric surgery. Springer, New York, pp 92–104CrossRef Katlic MR (2001) Principles of geriatric surgery. In: Rosenthal RA, Zenilman ME, Katlic MR (eds) Principles and practice of geriatric surgery. Springer, New York, pp 92–104CrossRef
2.
Zurück zum Zitat Duron JJ, Duron E, Maneglia R (2005) Digestive surgery in the elderly. J Chir (Paris) 142(3):50–159CrossRef Duron JJ, Duron E, Maneglia R (2005) Digestive surgery in the elderly. J Chir (Paris) 142(3):50–159CrossRef
3.
Zurück zum Zitat Turrentine FE, Wang H, Simpson VB et al (2006) Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg 203(6):865–877CrossRefPubMed Turrentine FE, Wang H, Simpson VB et al (2006) Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg 203(6):865–877CrossRefPubMed
4.
Zurück zum Zitat Walter LC, Covinsky KE (2001) Cancer screening in elderly patients: a framework for individualized decision making. JAMA 285(21):2750–2756CrossRefPubMed Walter LC, Covinsky KE (2001) Cancer screening in elderly patients: a framework for individualized decision making. JAMA 285(21):2750–2756CrossRefPubMed
5.
Zurück zum Zitat Smith OK (1967) Advanced age as a contraindication to operation. Med Rec (NY) 72:642–644 Smith OK (1967) Advanced age as a contraindication to operation. Med Rec (NY) 72:642–644
6.
Zurück zum Zitat Oschner A (1967) Is risk of operation too great in the elderly? Geriatrics 22(11):121–130 Oschner A (1967) Is risk of operation too great in the elderly? Geriatrics 22(11):121–130
7.
Zurück zum Zitat Wheatley BJ, Gorsuch JM, Ashraf Mansour M et al (2011) Vascular procedures in nonagenarians and centenarians are safe. Am J Surg 201(3):301–304CrossRefPubMed Wheatley BJ, Gorsuch JM, Ashraf Mansour M et al (2011) Vascular procedures in nonagenarians and centenarians are safe. Am J Surg 201(3):301–304CrossRefPubMed
8.
Zurück zum Zitat Arenal JJ, Bengoechea-Beeby M (2003) Mortality associated with emergency abdominal surgery in the elderly. Can J Surg 46(2):111–116PubMedPubMedCentral Arenal JJ, Bengoechea-Beeby M (2003) Mortality associated with emergency abdominal surgery in the elderly. Can J Surg 46(2):111–116PubMedPubMedCentral
9.
Zurück zum Zitat Pelavski AD, Lacasta A, de Miguel M et al (2013) Mortality and surgical risk assessment among the extreme old undergoing emergency surgery. Am J Surg 205(1):58–63CrossRefPubMed Pelavski AD, Lacasta A, de Miguel M et al (2013) Mortality and surgical risk assessment among the extreme old undergoing emergency surgery. Am J Surg 205(1):58–63CrossRefPubMed
10.
Zurück zum Zitat Hall WH, Ramachandran R, Narayan S et al (2004) An electronic application for rapidly calculating Charlson comorbidity score. BMC Cancer 20(4):94CrossRef Hall WH, Ramachandran R, Narayan S et al (2004) An electronic application for rapidly calculating Charlson comorbidity score. BMC Cancer 20(4):94CrossRef
11.
Zurück zum Zitat Evans DC, Cook CH, Christy JM et al (2012) Comorbidity-polypharmacy scoring facilitates outcome prediction in older trauma patients. J Am Geriatr Soc 60(8):1465–1470CrossRefPubMed Evans DC, Cook CH, Christy JM et al (2012) Comorbidity-polypharmacy scoring facilitates outcome prediction in older trauma patients. J Am Geriatr Soc 60(8):1465–1470CrossRefPubMed
12.
Zurück zum Zitat Mirbagheri N, Dark JG, Watters DA (2010) How do patients aged 85 and older fare with abdominal surgery? J Am Geriatr Soc 58(1):104–108CrossRefPubMed Mirbagheri N, Dark JG, Watters DA (2010) How do patients aged 85 and older fare with abdominal surgery? J Am Geriatr Soc 58(1):104–108CrossRefPubMed
13.
Zurück zum Zitat Frenkel WJ, Jongerius EJ, Mandjes-van Uitert ML et al (2014) Validation of the Charlson Comorbidity Index in acutely hospitalized elderly adults: a prospective cohort study. J Am Geriatr Soc 62(2):342–346CrossRefPubMed Frenkel WJ, Jongerius EJ, Mandjes-van Uitert ML et al (2014) Validation of the Charlson Comorbidity Index in acutely hospitalized elderly adults: a prospective cohort study. J Am Geriatr Soc 62(2):342–346CrossRefPubMed
14.
Zurück zum Zitat Duron JJ, Duron E, Dugue T et al (2011) Risk factors for mortality in major digestive surgery in the elderly: a multicenter prospective study. Ann Surg 254(2):375–382CrossRefPubMed Duron JJ, Duron E, Dugue T et al (2011) Risk factors for mortality in major digestive surgery in the elderly: a multicenter prospective study. Ann Surg 254(2):375–382CrossRefPubMed
15.
16.
Zurück zum Zitat Gürleyik G, Gürleyik E, Unalmişer S (2002) Abdominal surgical emergency in the elderly. Turk J Gastroenterol 13(1):47–52PubMed Gürleyik G, Gürleyik E, Unalmişer S (2002) Abdominal surgical emergency in the elderly. Turk J Gastroenterol 13(1):47–52PubMed
17.
Zurück zum Zitat Nishida K, Okinaga K, Miyazawa Y et al (2000) Emergency abdominal surgery in patients aged 80 years and older. Surg Today 30(1):22–27CrossRefPubMed Nishida K, Okinaga K, Miyazawa Y et al (2000) Emergency abdominal surgery in patients aged 80 years and older. Surg Today 30(1):22–27CrossRefPubMed
19.
Zurück zum Zitat Green G, Shaikh I, Fernandes R et al (2013) Emergency laparotomy in octogenarians: a 5-year study of morbidity and mortality. World J Gastrointest Surg 5(7):216–221CrossRefPubMedPubMedCentral Green G, Shaikh I, Fernandes R et al (2013) Emergency laparotomy in octogenarians: a 5-year study of morbidity and mortality. World J Gastrointest Surg 5(7):216–221CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Rubinfeld I, Thomas C, Berry S et al (2009) Octogenarian abdominal surgical emergencies: not so grim a problem with the acute care surgery model? J Trauma 67(5):983–989CrossRefPubMed Rubinfeld I, Thomas C, Berry S et al (2009) Octogenarian abdominal surgical emergencies: not so grim a problem with the acute care surgery model? J Trauma 67(5):983–989CrossRefPubMed
21.
Zurück zum Zitat Racz J, Dubois L, Katchky A et al (2012) Elective and emergency abdominal surgery in patients 90 years of age or older. Can J Surg 55(5):322–328CrossRefPubMedPubMedCentral Racz J, Dubois L, Katchky A et al (2012) Elective and emergency abdominal surgery in patients 90 years of age or older. Can J Surg 55(5):322–328CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Merani S, Payne J, Padwal RS et al (2014) Predictors of in-hospital mortality and complications in very elderly patients undergoing emergency surgery. World J Emerg Surg 7(9):43CrossRef Merani S, Payne J, Padwal RS et al (2014) Predictors of in-hospital mortality and complications in very elderly patients undergoing emergency surgery. World J Emerg Surg 7(9):43CrossRef
24.
Zurück zum Zitat Du Y, Karvellas CJ, Baracos V et al (2014) Acute Care and Emergency Surgery (ACES) Group. Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery. Surgery 156(3):521–527CrossRefPubMed Du Y, Karvellas CJ, Baracos V et al (2014) Acute Care and Emergency Surgery (ACES) Group. Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery. Surgery 156(3):521–527CrossRefPubMed
25.
Zurück zum Zitat Cooper Z, Mitchell SL, Gorges RJ et al (2015) Predictors of mortality up to 1 year after emergency major abdominal surgery in older adults. J Am Geriatr Soc 63(12):2572–2579CrossRefPubMedPubMedCentral Cooper Z, Mitchell SL, Gorges RJ et al (2015) Predictors of mortality up to 1 year after emergency major abdominal surgery in older adults. J Am Geriatr Soc 63(12):2572–2579CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Clegg A, Young J, Iliffe S et al (2013) Frailty in elderly people. Lancet 381(9868):752–762CrossRefPubMed Clegg A, Young J, Iliffe S et al (2013) Frailty in elderly people. Lancet 381(9868):752–762CrossRefPubMed
27.
Zurück zum Zitat Farhat JS, Velanovich V, Falvo AJ et al (2012) Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly. J Trauma Acute Care Surg 72(6):1526–1530CrossRefPubMed Farhat JS, Velanovich V, Falvo AJ et al (2012) Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly. J Trauma Acute Care Surg 72(6):1526–1530CrossRefPubMed
28.
Zurück zum Zitat Chen CC, Chen CN, Lai IR et al (2014) Effects of a modified hospital elder life program on frailty in individuals undergoing major elective abdominal surgery. J Am Geriatr Soc 62(2):261–268CrossRefPubMedPubMedCentral Chen CC, Chen CN, Lai IR et al (2014) Effects of a modified hospital elder life program on frailty in individuals undergoing major elective abdominal surgery. J Am Geriatr Soc 62(2):261–268CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat Arora VM, McGory ML, Fung CH (2007) Quality indicators for hospitalization and surgery in vulnerable elders. J Am Geriatr Soc 55(Suppl 2):S347–S358CrossRefPubMed Arora VM, McGory ML, Fung CH (2007) Quality indicators for hospitalization and surgery in vulnerable elders. J Am Geriatr Soc 55(Suppl 2):S347–S358CrossRefPubMed
30.
Zurück zum Zitat Desserud KF, Veen T, Søreide K (2016) Emergency general surgery in the geriatric patient. Br J Surg 103(2):e52–e61CrossRefPubMed Desserud KF, Veen T, Søreide K (2016) Emergency general surgery in the geriatric patient. Br J Surg 103(2):e52–e61CrossRefPubMed
31.
Zurück zum Zitat Ghaferi AA, Birkmeyer JD, Dimick JB (2009) Variation in hospital mortality associated with inpatient surgery. N Engl J Med 361(14):1368–1375CrossRefPubMed Ghaferi AA, Birkmeyer JD, Dimick JB (2009) Variation in hospital mortality associated with inpatient surgery. N Engl J Med 361(14):1368–1375CrossRefPubMed
32.
Zurück zum Zitat Buettner S, Gani F, Amini N et al (2016) The relative effect of hospital and surgeon volume on failure to rescue among patients undergoing liver resection for cancer. Surgery 159(4):1004–1012CrossRefPubMed Buettner S, Gani F, Amini N et al (2016) The relative effect of hospital and surgeon volume on failure to rescue among patients undergoing liver resection for cancer. Surgery 159(4):1004–1012CrossRefPubMed
33.
Zurück zum Zitat Rix TE, Bates T (2007) Pre-operative risk scores for the prediction of outcome in elderly people who require emergency surgery. World J Emerg Surg 5(2):16CrossRef Rix TE, Bates T (2007) Pre-operative risk scores for the prediction of outcome in elderly people who require emergency surgery. World J Emerg Surg 5(2):16CrossRef
Metadaten
Titel
Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies
verfasst von
Hassen Hentati
Chady Salloum
Philippe Caillet
Eylon Lahat
Mara Disabato
Eric Levesque
Philippe Compagnon
Chetana Lim
Daniel Azoulay
Publikationsdatum
30.12.2017
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 7/2018
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-017-4419-3

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