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CardioVascular and Interventional Radiology

Erschienen in:

01.02.2014 | Clinical Investigation

Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up

verfasst von: Giovanni Carlo Anselmetti, Antonio Manca, Stefano Marcia, Gabriele Chiara, Stefano Marini, Gamal Baroud, Daniele Regge, Filippo Montemurro

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 1/2014

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Abstract

Purpose

This study was designed to assess the clinical outcomes of patients treated by vertebral augmentation with nitinol endoprosthesis (VNE) to treat painful vertebral compression fractures.

Methods

Forty patients with one or more painful osteoporotic VCF, confirmed by MRI and accompanied by back-pain unresponsive to a minimum 2 months of conservative medical treatment, underwent VNE at 42 levels. Preoperative and postoperative pain measured with Visual Analog Scale (VAS), disability measured by Oswestry Disability Index (ODI), and vertebral height restoration (measured with 2-dimensional reconstruction CT) were compared at last follow-up (average follow-up 15 months). Cement extravasation, subsequent fractures, and implant migration were recorded.

Results

Long-term follow-up was obtained in 38 of 40 patients. Both VAS and ODI significantly improved from a median of 8.0 (range 5–10) and 66 % (range 44–88 %) to 0.5 (range 0–8) and 6 % (range 6–66 %), respectively, at 1 year (p < 0.0001). Vertebral height measurements comparing time points increased in a statistically significant manner (ANOVA, p < 0.001). Overall cement extravasation rate was 9.5 %. Discal and venous leakage rates were 7.1 and 0 % respectively. No symptomatic extravasations occurred. Five of 38 (13.1 %) patients experienced new spontaneous, osteoporotic fractures. No device change or migration was observed.

Conclusions

VNE is a safe and effective procedure that is able to provide long-lasting pain relief and durable vertebral height gain with a low rate of new fractures and cement leakages.

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Titel: Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up
verfasst von: Giovanni Carlo Anselmetti
Antonio Manca
Stefano Marcia
Gabriele Chiara
Stefano Marini
Gamal Baroud
Daniele Regge
Filippo Montemurro
Publikationsdatum: 01.02.2014
Verlag: Springer US
Erschienen in: CardioVascular and Interventional Radiology / Ausgabe 1/2014
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-013-0623-1

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Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up