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Erschienen in: Archives of Gynecology and Obstetrics 2/2009

01.02.2009 | Original Article

Maternal periodontal status and preterm low birth weight delivery: a case–control study

verfasst von: Yousef Khader, Lamis Al-shishani, Basil Obeidat, Mohammad Khassawneh, Samar Burgan, Zouhair O. Amarin, Mousa Alomari, Ahmad Alkafajei

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2009

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Abstract

Objectives

To assess the association between severity and extent of maternal periodontal disease and preterm birth/low birth weight (PLBW) among women in the north of Jordan.

Methods

A total of 148 woman who gave preterm birth/low birth weight birth and 438 women with uncomplicated full term vaginal delivery were included in this study. Socio-demographic characteristics, antenatal history, medical history, and family medical history were collected through personal interview or abstracted from maternal records. The oral hygiene status, and periodontal and dental parameters were assessed for all women.

Results

The average of probing pocket depth (PPD) and average of clinical attachment level (CAL) were significantly higher among women who gave PLBW babies. The mean gingival recession was not significantly different between the two groups. The percentages of sites with PPD ≥ 3 mm and CAL ≥ 3 mm were significantly higher among women who gave PLBW babies. Number of decayed teeth, number filled teeth, and number of missing teeth showed no significant association with PLBW delivery.

Conclusion

The extent and severity of periodontal diseases appeared to be associated with increased odds of PLBW delivery. Nevertheless, more and larger intervention trials are needed before it can be fully accepted that periodontal infection is a true risk factor for PLBW.
Literatur
1.
Zurück zum Zitat United Nation’s Children’s Fund and World Health Organization (2004) Low birth weight: country, regional and global estimates. UNICEF, New York United Nation’s Children’s Fund and World Health Organization (2004) Low birth weight: country, regional and global estimates. UNICEF, New York
2.
3.
Zurück zum Zitat Romero R, Wu YK, Mazor M, Hobbins JC, Mitchell MD (1988) Amniotic fluid prostaglandin E2 in preterm labor. Prostaglandins Leukot Essent Fatty Acids 34:141–145PubMedCrossRef Romero R, Wu YK, Mazor M, Hobbins JC, Mitchell MD (1988) Amniotic fluid prostaglandin E2 in preterm labor. Prostaglandins Leukot Essent Fatty Acids 34:141–145PubMedCrossRef
4.
Zurück zum Zitat Buduneli N, Baylas H, Buduneli E, Turkoglu O, Kose T, Dahlen G (2005) Periodontal infections and pre-term low birth weight: a case-control study. J Clin Periodontol 32:174–181PubMedCrossRef Buduneli N, Baylas H, Buduneli E, Turkoglu O, Kose T, Dahlen G (2005) Periodontal infections and pre-term low birth weight: a case-control study. J Clin Periodontol 32:174–181PubMedCrossRef
5.
Zurück zum Zitat Moore S, Ide M, Coward PY, Randhawa M, Borkowska E, Baylis R, Wilson RF (2004) A prospective study to investigate the relationship between periodontal disease and adverse pregnancy outcome. Br Dent J 197:251–258PubMedCrossRef Moore S, Ide M, Coward PY, Randhawa M, Borkowska E, Baylis R, Wilson RF (2004) A prospective study to investigate the relationship between periodontal disease and adverse pregnancy outcome. Br Dent J 197:251–258PubMedCrossRef
6.
Zurück zum Zitat Dörtbudak O, Eberhardt R, Ulm M, Persson GR (2005) Periodontitis, a marker of risk in pregnancy for preterm birth. J Clin Periodontol 32:45–52PubMedCrossRef Dörtbudak O, Eberhardt R, Ulm M, Persson GR (2005) Periodontitis, a marker of risk in pregnancy for preterm birth. J Clin Periodontol 32:45–52PubMedCrossRef
7.
Zurück zum Zitat Davenport ES, Williams CE, Sterne JA, Murad S, Sivapathasundram V, Curtis MA (2002) Maternal periodontal disease and preterm low birth weight: case–control study. J Dent Res 81:313–318PubMedCrossRef Davenport ES, Williams CE, Sterne JA, Murad S, Sivapathasundram V, Curtis MA (2002) Maternal periodontal disease and preterm low birth weight: case–control study. J Dent Res 81:313–318PubMedCrossRef
8.
Zurück zum Zitat Mokeem SA, Molla GN, Al-Jewair TS (2004) The prevalence and relationship between periodontal disease and pre-term low birth weight infants at King Khalid University Hospital in Riyadh, Saudi Arabia. J Contemp Dent Pract 5:40–56PubMed Mokeem SA, Molla GN, Al-Jewair TS (2004) The prevalence and relationship between periodontal disease and pre-term low birth weight infants at King Khalid University Hospital in Riyadh, Saudi Arabia. J Contemp Dent Pract 5:40–56PubMed
9.
Zurück zum Zitat López NJ, Smith PC, Gutierrez J (2002) Higher risk of preterm birth and low birth weight in women with periodontal disease. J Dent Res 81:58–63PubMedCrossRef López NJ, Smith PC, Gutierrez J (2002) Higher risk of preterm birth and low birth weight in women with periodontal disease. J Dent Res 81:58–63PubMedCrossRef
10.
11.
12.
Zurück zum Zitat McGaw T (2002) Periodontal disease and preterm delivery of low-birth-weight infants. J Can Dent Assoc 68:165–169PubMed McGaw T (2002) Periodontal disease and preterm delivery of low-birth-weight infants. J Can Dent Assoc 68:165–169PubMed
13.
Zurück zum Zitat Carta G, Persia G, Falciglia K, Iovenitti P (2004) Periodontal disease and poor obstetrical outcome. Clin Exp Obstet Gynecol 31:47–49PubMed Carta G, Persia G, Falciglia K, Iovenitti P (2004) Periodontal disease and poor obstetrical outcome. Clin Exp Obstet Gynecol 31:47–49PubMed
14.
Zurück zum Zitat Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S (2006) Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG 113:135–143PubMedCrossRef Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S (2006) Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG 113:135–143PubMedCrossRef
15.
Zurück zum Zitat Vergnes JN, Sixou M (2007) Preterm low birth weight and maternal periodontal status: a meta-analysis. Am J Obstet Gynecol 196:135.e1–7. Vergnes JN, Sixou M (2007) Preterm low birth weight and maternal periodontal status: a meta-analysis. Am J Obstet Gynecol 196:135.e1–7.
16.
Zurück zum Zitat Hill GB (1998) Preterm birth: associations with genital and possibly oral microflora. Ann Periodontol 3:222–232PubMed Hill GB (1998) Preterm birth: associations with genital and possibly oral microflora. Ann Periodontol 3:222–232PubMed
17.
Zurück zum Zitat Lin D, Smith MA, Elter J, Champagne C, Downey CL, Beck J, Offenbacher S (2003) Porphyromonas gingivalis infection in pregnant mice is associated with placental dissemination, an increase in the placental Th1/Th2 cytokine ratio, and fetal growth restriction. Infect Immun 71:5163–5168PubMedCrossRef Lin D, Smith MA, Elter J, Champagne C, Downey CL, Beck J, Offenbacher S (2003) Porphyromonas gingivalis infection in pregnant mice is associated with placental dissemination, an increase in the placental Th1/Th2 cytokine ratio, and fetal growth restriction. Infect Immun 71:5163–5168PubMedCrossRef
18.
Zurück zum Zitat Pretorius C, Jagatt A, Lamont RF (2007) The relationship between periodontal disease, bacterial vaginosis, and preterm birth. J Perinat Med 35:93–99PubMedCrossRef Pretorius C, Jagatt A, Lamont RF (2007) The relationship between periodontal disease, bacterial vaginosis, and preterm birth. J Perinat Med 35:93–99PubMedCrossRef
19.
Zurück zum Zitat Boggess KA, Moss K, Madianos P, Murtha AP, Beck J, Offenbacher S (2005) Fetal immune response to oral pathogens and risk of preterm birth. Am J Obstet Gynecol 193:1121–1126PubMedCrossRef Boggess KA, Moss K, Madianos P, Murtha AP, Beck J, Offenbacher S (2005) Fetal immune response to oral pathogens and risk of preterm birth. Am J Obstet Gynecol 193:1121–1126PubMedCrossRef
20.
Zurück zum Zitat Moutsopoulos NM, Madianos PN (2006) Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections. Ann N Y Acad Sci 1088:251–264PubMedCrossRef Moutsopoulos NM, Madianos PN (2006) Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections. Ann N Y Acad Sci 1088:251–264PubMedCrossRef
21.
Zurück zum Zitat Madianos PN, Lieff S, Murtha AP, Boggess KA, Auten RL Jr, Beck JD, Offenbacher S (2001) Maternal periodontitis and prematurity. Part II: maternal infection and fetal exposure. Ann Periodontol 6:175–182PubMedCrossRef Madianos PN, Lieff S, Murtha AP, Boggess KA, Auten RL Jr, Beck JD, Offenbacher S (2001) Maternal periodontitis and prematurity. Part II: maternal infection and fetal exposure. Ann Periodontol 6:175–182PubMedCrossRef
Metadaten
Titel
Maternal periodontal status and preterm low birth weight delivery: a case–control study
verfasst von
Yousef Khader
Lamis Al-shishani
Basil Obeidat
Mohammad Khassawneh
Samar Burgan
Zouhair O. Amarin
Mousa Alomari
Ahmad Alkafajei
Publikationsdatum
01.02.2009
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 2/2009
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-008-0696-2

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