Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 3/2010

01.03.2010 | Gynecologic oncology

Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy

verfasst von: Helen Diana Budiman, Alexander Burges, Ina M. Rühl, Klaus Friese, Uwe Hasbargen

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2010

Einloggen, um Zugang zu erhalten

Abstract

Background

A rare complication of mature cystic teratoma of the ovary is malignant transformation, mostly being squamous cell carcinoma (SCC). Due to small case series, there are no established standard surgical and postoperative procedures.

Case

A 41-year-old pregnant woman presented with a right ovarian tumour. At 14 weeks of gestation, laparotomy with oophorectomy was performed. Histology revealed a pT1a poorly differentiated SCC with lymphovascular invasion. She delivered a healthy infant at 39 weeks of gestation. Nine weeks after delivery, she underwent complete surgical resection and was staged pT1a, pN0 (0/40) pMx, G0. No further treatment was given and 37 months later she is still free of disease.

Conclusion

For this rare entity complete surgical resection seems to be a safe treatment.
Literatur
1.
Zurück zum Zitat Peterson WF, Prevost EC, Edmunds FT, Hundley JM, Morris FK (1955) Benign cystic tumours of the ovary: a clinicostatistical study of 1007 cases with a review of the literature. Am J Obstet Gynecol 70:386–82 Peterson WF, Prevost EC, Edmunds FT, Hundley JM, Morris FK (1955) Benign cystic tumours of the ovary: a clinicostatistical study of 1007 cases with a review of the literature. Am J Obstet Gynecol 70:386–82
2.
Zurück zum Zitat Whitecar MP, Turner S, Higby MK (1999) Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181:19–24CrossRefPubMed Whitecar MP, Turner S, Higby MK (1999) Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181:19–24CrossRefPubMed
3.
Zurück zum Zitat Usui R, Minakami H, Kosuge S, Iwasaki R, Ohwada M, Sato I (2000) A retrospective survey of clinical, pathologic and prognostic features of adnexal masses operated on during pregnancy. J Obstet Gynaecol Res 26:89–93PubMedCrossRef Usui R, Minakami H, Kosuge S, Iwasaki R, Ohwada M, Sato I (2000) A retrospective survey of clinical, pathologic and prognostic features of adnexal masses operated on during pregnancy. J Obstet Gynaecol Res 26:89–93PubMedCrossRef
4.
Zurück zum Zitat Stamp GWH, McConnell EM (1983) Malignancy rising in cystic ovarian teratomas. A report of 24 cases. Br J Obstet Gynaecol 90:671–675PubMed Stamp GWH, McConnell EM (1983) Malignancy rising in cystic ovarian teratomas. A report of 24 cases. Br J Obstet Gynaecol 90:671–675PubMed
5.
Zurück zum Zitat Oehler MK, Wain GV, Brand A (2003) Gynaecological malignancies in pregnancy: a review. Aust NZ J Obstet Gynaecol 43:414–420CrossRef Oehler MK, Wain GV, Brand A (2003) Gynaecological malignancies in pregnancy: a review. Aust NZ J Obstet Gynaecol 43:414–420CrossRef
6.
Zurück zum Zitat Kikkawa F, Ishikawa H, Tamakoshi K, Nawa A, Suganuma N, Tomoda Y (1997) Squamous cell carcinoma arising from mature cystic teratoma of the ovary: a clinicopathologic analysis. Obstet Gynecol 89:823–833CrossRef Kikkawa F, Ishikawa H, Tamakoshi K, Nawa A, Suganuma N, Tomoda Y (1997) Squamous cell carcinoma arising from mature cystic teratoma of the ovary: a clinicopathologic analysis. Obstet Gynecol 89:823–833CrossRef
7.
Zurück zum Zitat Pins MR, Young RH, Daly WJ, Scully RE (1996) Primary squamous cell carcinoma of the ovary. A report of 37 cases. Am J Surg Pathol 20:823–833CrossRefPubMed Pins MR, Young RH, Daly WJ, Scully RE (1996) Primary squamous cell carcinoma of the ovary. A report of 37 cases. Am J Surg Pathol 20:823–833CrossRefPubMed
8.
Zurück zum Zitat Mori Y, Nishii H, Takabe K et al (2003) Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary. Gyn Oncol 90:338–341CrossRef Mori Y, Nishii H, Takabe K et al (2003) Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary. Gyn Oncol 90:338–341CrossRef
9.
Zurück zum Zitat Miyasaki K, Tokunga T, Katabuchi H, Ohba T, Tashiro H, Okamura H (1991) Clinical usefulness of serum squamous cell carcinoma antigen for early detection of squamous cell carcinoma arising in mature cystic teratoma of the ovary. Obstet Gynecol 78:562–565 Miyasaki K, Tokunga T, Katabuchi H, Ohba T, Tashiro H, Okamura H (1991) Clinical usefulness of serum squamous cell carcinoma antigen for early detection of squamous cell carcinoma arising in mature cystic teratoma of the ovary. Obstet Gynecol 78:562–565
10.
Zurück zum Zitat Spitzer M, Kaushal N, Benjamin F (1998) Maternal CA 125 levels in pregnancy and the puerperium. J Reprod Med 43:387–393PubMed Spitzer M, Kaushal N, Benjamin F (1998) Maternal CA 125 levels in pregnancy and the puerperium. J Reprod Med 43:387–393PubMed
11.
Zurück zum Zitat Kido A, Togashi K, Konishi I, Kataoka ML, Koyama T, Ueda H et al (1999) Dermoid cysts of the ovary with malignant transformation: MR appearance. Am J Roentgenol 172(2):445–449 Kido A, Togashi K, Konishi I, Kataoka ML, Koyama T, Ueda H et al (1999) Dermoid cysts of the ovary with malignant transformation: MR appearance. Am J Roentgenol 172(2):445–449
12.
Zurück zum Zitat Leiserowitz G (2006) Managing ovarian masses during pregnancy. Obstet Gynecol Surv 61(7):463–470CrossRefPubMed Leiserowitz G (2006) Managing ovarian masses during pregnancy. Obstet Gynecol Surv 61(7):463–470CrossRefPubMed
13.
Zurück zum Zitat Mayer C, Miller DM, Ehlen TG (2002) Peritoneal implantation of squamous cell carcinoma following rupture of a dermoid cyst during laparoscopic removal. Gynecol Oncol 84:1–183CrossRef Mayer C, Miller DM, Ehlen TG (2002) Peritoneal implantation of squamous cell carcinoma following rupture of a dermoid cyst during laparoscopic removal. Gynecol Oncol 84:1–183CrossRef
14.
Zurück zum Zitat Tseng C, Chou H, Huang K et al (1996) Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Gynecol Oncol 63:364–370CrossRefPubMed Tseng C, Chou H, Huang K et al (1996) Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Gynecol Oncol 63:364–370CrossRefPubMed
15.
Zurück zum Zitat Mekaru K, Kamiyama S, Masamoto H et al (2008) Squamous cell carcinoma arising in an ovarian mature cystic teratoma complicating pregnancy: a case report. Arch Gynecol Obstet 278:287–290CrossRefPubMed Mekaru K, Kamiyama S, Masamoto H et al (2008) Squamous cell carcinoma arising in an ovarian mature cystic teratoma complicating pregnancy: a case report. Arch Gynecol Obstet 278:287–290CrossRefPubMed
16.
Zurück zum Zitat Rose PG, Tak WK, Reale FR (1993) Squamous cell carcinoma arising in a mature cystic teratoma with metastasis to the paraaortic nodes. Gynecol Oncol 50(1):131–133CrossRefPubMed Rose PG, Tak WK, Reale FR (1993) Squamous cell carcinoma arising in a mature cystic teratoma with metastasis to the paraaortic nodes. Gynecol Oncol 50(1):131–133CrossRefPubMed
17.
Zurück zum Zitat Dos Santos L et al (2007) Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and review of the literature. Gynecol Oncol 105(2):321–324CrossRefPubMed Dos Santos L et al (2007) Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and review of the literature. Gynecol Oncol 105(2):321–324CrossRefPubMed
Metadaten
Titel
Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy
verfasst von
Helen Diana Budiman
Alexander Burges
Ina M. Rühl
Klaus Friese
Uwe Hasbargen
Publikationsdatum
01.03.2010
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 3/2010
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1193-y

Weitere Artikel der Ausgabe 3/2010

Archives of Gynecology and Obstetrics 3/2010 Zur Ausgabe

Antikörper-Wirkstoff-Konjugat hält solide Tumoren in Schach

16.05.2024 Zielgerichtete Therapie Nachrichten

Trastuzumab deruxtecan scheint auch jenseits von Lungenkrebs gut gegen solide Tumoren mit HER2-Mutationen zu wirken. Dafür sprechen die Daten einer offenen Pan-Tumor-Studie.

Mammakarzinom: Senken Statine das krebsbedingte Sterberisiko?

15.05.2024 Mammakarzinom Nachrichten

Frauen mit lokalem oder metastasiertem Brustkrebs, die Statine einnehmen, haben eine niedrigere krebsspezifische Mortalität als Patientinnen, die dies nicht tun, legen neue Daten aus den USA nahe.

S3-Leitlinie zur unkomplizierten Zystitis: Auf Antibiotika verzichten?

15.05.2024 Harnwegsinfektionen Nachrichten

Welche Antibiotika darf man bei unkomplizierter Zystitis verwenden und wovon sollte man die Finger lassen? Welche pflanzlichen Präparate können helfen? Was taugt der zugelassene Impfstoff? Antworten vom Koordinator der frisch überarbeiteten S3-Leitlinie, Prof. Florian Wagenlehner.

Gestationsdiabetes: In der zweiten Schwangerschaft folgenreicher als in der ersten

13.05.2024 Gestationsdiabetes Nachrichten

Das Risiko, nach einem Gestationsdiabetes einen Typ-2-Diabetes zu entwickeln, hängt nicht nur von der Zahl, sondern auch von der Reihenfolge der betroffenen Schwangerschaften ab.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.