Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 2/2011

01.02.2011 | Materno-fetal Medicine

Influence of self-reported snoring and witnessed sleep apnea on gestational hypertension and fetal outcome in pregnancy

verfasst von: Aylin Ayrım, Esra Aktepe Keskin, Duygu Ozol, Yuksel Onaran, Zeki Yıldırım, Hasan Kafali

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2011

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Hormonal and physical changes during pregnancy are associated with some sleep-related breathing disorders (SRBD) such as snoring and sleep apnea, and SRBD are associated with recurrent episodes of oxyhemoglobin desaturation and increased sympathic activity. We aimed to search the incidence of self-reported snoring and witnessed apnea in the third trimester of pregnancy and to analyze their influence on fetal outcome and gestational hypertension (GH).

Methods

Two hundred pregnant women (group 1) during their stay for labor and 200 age-matched control women (group 2) were included in the study. All patients were asked to complete a detailed questionnaire that covers demographic features. We measured neck circumference and performed Epworth sleepiness scale (ESS) to determine excessive daytime sleepiness in all patients.

Results

The mean age was 27.4 ± 6.7 and 26.3 ± 5.8 for group 1 and 2, respectively. Habitual snoring was detected only in group 1 in 5 patients; 36 pregnant women and 7 control patients reported occasional snoring. Both habitual and occasional snoring was significantly observed to be increased in pregnancy. Witnessed sleep apnea was been observed only in 1 patient in group 1. The mean neck circumference was 37.4 ± 3.2, 35.1 ± 2.1 cm and ESS was 6.7 ± 3.01, 5.1 ± 2.1 for group 1 and 2, respectively (p < 0.05). There was no significant correlation between snoring and GH. There was no significant relationship between all investigated parameters and fetal outcome. We found that excessive weight gain during pregnancy is significantly associated with snoring.

Conclusion

We concluded that, although pregnant women, especially who gain excessive weight during their pregnancy, significantly snore more than nonpregnant women, this did not affect fetal outcome.
Literatur
1.
Zurück zum Zitat Partinen M, Gislason T (1995) Basic Nordic Sleep Questionnaire (BNSQ): a quantitated measure of subjective sleep complaints. J Sleep Res 4(S1):150–155CrossRefPubMed Partinen M, Gislason T (1995) Basic Nordic Sleep Questionnaire (BNSQ): a quantitated measure of subjective sleep complaints. J Sleep Res 4(S1):150–155CrossRefPubMed
2.
Zurück zum Zitat Gislason T, Almqvist M, Eriksson G, Taube A, Boman G (1988) Prevalence of sleep apnea syndrome among Swedish men—an epidemiological study. J Clin Epidemiol 41(6):571–576CrossRefPubMed Gislason T, Almqvist M, Eriksson G, Taube A, Boman G (1988) Prevalence of sleep apnea syndrome among Swedish men—an epidemiological study. J Clin Epidemiol 41(6):571–576CrossRefPubMed
3.
Zurück zum Zitat Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed
4.
Zurück zum Zitat Venkata C, Venkateshiah SB (2009) Sleep-disordered breathing during pregnancy. J Am Board Fam Med 22(2):158–168CrossRefPubMed Venkata C, Venkateshiah SB (2009) Sleep-disordered breathing during pregnancy. J Am Board Fam Med 22(2):158–168CrossRefPubMed
5.
Zurück zum Zitat Contreras G, Gutiérrez M, Beroíza T, Fantín A, Oddó H, Villarroel L, Cruz E, Lisboa C (1991) Ventilatory drive and respiratory muscle function in pregnancy. Am Rev Respir Dis 144(4):837–841PubMed Contreras G, Gutiérrez M, Beroíza T, Fantín A, Oddó H, Villarroel L, Cruz E, Lisboa C (1991) Ventilatory drive and respiratory muscle function in pregnancy. Am Rev Respir Dis 144(4):837–841PubMed
6.
Zurück zum Zitat Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, Benjamin A, Kimoff RJ (2009) Obstructive sleep apnoea and its association with gestational hypertension. Eur Respir J 33(3):559–565CrossRefPubMed Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, Benjamin A, Kimoff RJ (2009) Obstructive sleep apnoea and its association with gestational hypertension. Eur Respir J 33(3):559–565CrossRefPubMed
7.
Zurück zum Zitat Sulit L, Storfer-Isser A, Kirchner HL, Redline S (2006) Differences in polysomnography predictors for hypertension and impaired glucose tolerance. Sleep 29(6):777–783PubMed Sulit L, Storfer-Isser A, Kirchner HL, Redline S (2006) Differences in polysomnography predictors for hypertension and impaired glucose tolerance. Sleep 29(6):777–783PubMed
8.
Zurück zum Zitat Narkiewicz K, Wolf J, Lopez-Jimenez F, Somers VK (2005) Obstructive sleep apnea and hypertension. Curr Cardiol Rep 7(6):435–440CrossRefPubMed Narkiewicz K, Wolf J, Lopez-Jimenez F, Somers VK (2005) Obstructive sleep apnea and hypertension. Curr Cardiol Rep 7(6):435–440CrossRefPubMed
9.
Zurück zum Zitat Johns MW (1993) Daytime sleepiness, snoring, and obstructive sleep apnea. The Epworth Sleepiness Scale. Chest 103(1):30–36CrossRefPubMed Johns MW (1993) Daytime sleepiness, snoring, and obstructive sleep apnea. The Epworth Sleepiness Scale. Chest 103(1):30–36CrossRefPubMed
10.
Zurück zum Zitat Verdaguer M, Levrat V, Lamour C, Paquereau J, Neau JP, Meurice JC (2008) Obstructive sleep apnoea syndrome (OSAS) in women: a specific entity? Rev Mal Respir 25(10):1279–1288PubMed Verdaguer M, Levrat V, Lamour C, Paquereau J, Neau JP, Meurice JC (2008) Obstructive sleep apnoea syndrome (OSAS) in women: a specific entity? Rev Mal Respir 25(10):1279–1288PubMed
11.
Zurück zum Zitat Ursavas A, Karadag M, Nalci N, Ercan I, Gozu RO (2008) Self-reported snoring, maternal obesity and neck circumference as risk factors for pregnancy-induced hypertension and preeclampsia. Respiration 76(1):33–39CrossRefPubMed Ursavas A, Karadag M, Nalci N, Ercan I, Gozu RO (2008) Self-reported snoring, maternal obesity and neck circumference as risk factors for pregnancy-induced hypertension and preeclampsia. Respiration 76(1):33–39CrossRefPubMed
12.
Zurück zum Zitat Franklin KA, Holmgren PA, Jönsson F, Poromaa N, Stenlund H, Svanborg E (2000) Snoring, pregnancy-induced hypertension, and growth retardation of the fetus. Chest 117(1):137–141CrossRefPubMed Franklin KA, Holmgren PA, Jönsson F, Poromaa N, Stenlund H, Svanborg E (2000) Snoring, pregnancy-induced hypertension, and growth retardation of the fetus. Chest 117(1):137–141CrossRefPubMed
13.
Zurück zum Zitat Gislason T, Benediktsdóttir B, Björnsson JK, Kjartansson G, Kjeld M, Kristbjarnarson H (1993) Snoring, hypertension, and the sleep apnea syndrome. An epidemiologic survey of middle-aged women. Chest 103(4):1147–1151CrossRefPubMed Gislason T, Benediktsdóttir B, Björnsson JK, Kjartansson G, Kjeld M, Kristbjarnarson H (1993) Snoring, hypertension, and the sleep apnea syndrome. An epidemiologic survey of middle-aged women. Chest 103(4):1147–1151CrossRefPubMed
14.
Zurück zum Zitat Lefcourt LA, Rodis JF (1996) Obstructive sleep apnea in pregnancy. Obstet Gynecol Surv 51(8):503–506CrossRefPubMed Lefcourt LA, Rodis JF (1996) Obstructive sleep apnea in pregnancy. Obstet Gynecol Surv 51(8):503–506CrossRefPubMed
15.
Zurück zum Zitat Youssef HF, Dombrovskiy VY, Santiago TV, Nolledo MS (2007) Sleep apnea is associated with gestational diabetes mellitus and pregnancy-induced hypertension. Am J Respir Crit Care Med 175:A996 Youssef HF, Dombrovskiy VY, Santiago TV, Nolledo MS (2007) Sleep apnea is associated with gestational diabetes mellitus and pregnancy-induced hypertension. Am J Respir Crit Care Med 175:A996
16.
Zurück zum Zitat Sahin FK, Koken G, Cosar E, Saylan F, Fidan F, Yilmazer M, Unlu M (2008) Obstructive sleep apnea in pregnancy and fetal outcome. Int J Gynaecol Obstet 100(2):141–146CrossRefPubMed Sahin FK, Koken G, Cosar E, Saylan F, Fidan F, Yilmazer M, Unlu M (2008) Obstructive sleep apnea in pregnancy and fetal outcome. Int J Gynaecol Obstet 100(2):141–146CrossRefPubMed
17.
Zurück zum Zitat Yin TT, Williams N, Burton C, Ong SS, Loughna P, Britton JR, Thornton JG (2008) Hypertension, fetal growth restriction and obstructive sleep apnoea in pregnancy. Eur J Obstet Gynecol Reprod Biol 141(1):35–38CrossRefPubMed Yin TT, Williams N, Burton C, Ong SS, Loughna P, Britton JR, Thornton JG (2008) Hypertension, fetal growth restriction and obstructive sleep apnoea in pregnancy. Eur J Obstet Gynecol Reprod Biol 141(1):35–38CrossRefPubMed
18.
Zurück zum Zitat Köken G, Sahin FK, Cosar E, Saylan F, Yilmaz N, Altuntas I, Fidan F, Unlu M, Yilmazer M (2007) Oxidative stress markers in pregnant women who snore and fetal outcome: a case control study. Acta Obstet Gynecol Scand 86(11):1317–1321CrossRefPubMed Köken G, Sahin FK, Cosar E, Saylan F, Yilmaz N, Altuntas I, Fidan F, Unlu M, Yilmazer M (2007) Oxidative stress markers in pregnant women who snore and fetal outcome: a case control study. Acta Obstet Gynecol Scand 86(11):1317–1321CrossRefPubMed
19.
Zurück zum Zitat Loube DI, Poceta JS, Morales MC, Peacock MD, Mitler MM (1996) Self-reported snoring in pregnancy. Association with fetal outcome. Chest 109(4):885–889CrossRefPubMed Loube DI, Poceta JS, Morales MC, Peacock MD, Mitler MM (1996) Self-reported snoring in pregnancy. Association with fetal outcome. Chest 109(4):885–889CrossRefPubMed
20.
Zurück zum Zitat Bachour A, Teramo K, Hiilesmaa V, Maasilta P (2008) Increased plasma levels of inflammatory markers and upper airway resistance during sleep in pre-eclampsia. Sleep Med 9(6):667–674CrossRefPubMed Bachour A, Teramo K, Hiilesmaa V, Maasilta P (2008) Increased plasma levels of inflammatory markers and upper airway resistance during sleep in pre-eclampsia. Sleep Med 9(6):667–674CrossRefPubMed
21.
Zurück zum Zitat Bliwise DL, Nekich JC, Dement WC (1991) Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population. Chest 99(3):600–608CrossRefPubMed Bliwise DL, Nekich JC, Dement WC (1991) Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population. Chest 99(3):600–608CrossRefPubMed
22.
Zurück zum Zitat Stoohs RA, Blum HC, Haselhorst M, Duchna HW, Guilleminault C, Dement WC (1998) Normative data on snoring: a comparison between younger and older adults. Eur Respir J 11(2):451–457CrossRefPubMed Stoohs RA, Blum HC, Haselhorst M, Duchna HW, Guilleminault C, Dement WC (1998) Normative data on snoring: a comparison between younger and older adults. Eur Respir J 11(2):451–457CrossRefPubMed
Metadaten
Titel
Influence of self-reported snoring and witnessed sleep apnea on gestational hypertension and fetal outcome in pregnancy
verfasst von
Aylin Ayrım
Esra Aktepe Keskin
Duygu Ozol
Yuksel Onaran
Zeki Yıldırım
Hasan Kafali
Publikationsdatum
01.02.2011
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 2/2011
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1327-2

Weitere Artikel der Ausgabe 2/2011

Archives of Gynecology and Obstetrics 2/2011 Zur Ausgabe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bislang gibt es kein Medikament zur Prävention von Wochenbettdepressionen. Das Injektionsanästhetikum Esketamin könnte womöglich diese Lücke füllen.

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

22.04.2024 DGIM 2024 Kongressbericht

Durch die Häufung nach der COVID-19-Pandemie sind Infektionen mit dem Respiratorischen Synzytial-Virus (RSV) in den Fokus gerückt. Fachgesellschaften empfehlen eine Impfung inzwischen nicht nur für Säuglinge und Kleinkinder.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.