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Erschienen in: European Archives of Oto-Rhino-Laryngology 2/2015

01.02.2015 | Rhinology

Surgical management of recurrent sinonasal mucosal melanoma: endoscopic or transfacial resection

verfasst von: G. J. Ledderose, A. Leunig

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 2/2015

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Abstract

Sinonasal mucosal melanoma (SNMM) is associated with poor prognosis. Local recurrence is common and represents a major problem in the therapy. Wide resection surgery is usually applied. However, given the almost futile prognosis, optimal symptom control may be preferable to wide resection at all costs. The aim of our study was to analyze the outcome in patients with recurrent SNMM treated by transfacial radical surgery or by a less invasive endoscopically controlled approach. Patients with recurrent grade III or IV staged SNMM who presented to our ENT department between 2000 and 2010 were either treated by transfacial (n = 10) or endoscopically controlled surgery (n = 12). The patients’ charts were reviewed for clinical symptoms, relapse-free time and survival time. Clinical symptoms improved after surgery. The morbidity after endoscopic surgery was significantly lower than after transfacial surgery. The chosen surgical technique did neither affect relapse-free nor survival time. When treating recurrent SNMM, the comparatively gentle and less mutilating endoscopic approach proved to be a sufficient surgical procedure, being not inferior to aggressive surgery with respect to recurrence and survival rate.
Literatur
1.
Zurück zum Zitat Chang AE, Karnell LH, Menck HR (1998) The national cancer data base report on cutaneous and non cutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83:1664–1678PubMedCrossRef Chang AE, Karnell LH, Menck HR (1998) The national cancer data base report on cutaneous and non cutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83:1664–1678PubMedCrossRef
2.
Zurück zum Zitat Chiu NT, Weinstock MA (1996) Melanoma of oronasal mucosa. Population-based analysis of occurrence and mortality. Arch Otolaryngol Head Neck Surg 122:985–988PubMedCrossRef Chiu NT, Weinstock MA (1996) Melanoma of oronasal mucosa. Population-based analysis of occurrence and mortality. Arch Otolaryngol Head Neck Surg 122:985–988PubMedCrossRef
3.
Zurück zum Zitat Bradley PJ (2006) Primary malignant mucosal melanoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg 14:100–104PubMedCrossRef Bradley PJ (2006) Primary malignant mucosal melanoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg 14:100–104PubMedCrossRef
4.
Zurück zum Zitat Bridger AG, Smee D, Baldwin MA, Kwok B, Bridger GP (2005) Experience with mucosal melanoma of the nose and paranasal sinuses. ANZ J Surg 75(4):192–197PubMedCrossRef Bridger AG, Smee D, Baldwin MA, Kwok B, Bridger GP (2005) Experience with mucosal melanoma of the nose and paranasal sinuses. ANZ J Surg 75(4):192–197PubMedCrossRef
5.
Zurück zum Zitat Christopherson K, Malyapa RS, Werning JW, Morris CG, Kirwan J, Mendenhall WM (2013) Radiation therapy for mucosal melanoma of the head and neck. Am J Clin Oncol [Epub ahead of print] Christopherson K, Malyapa RS, Werning JW, Morris CG, Kirwan J, Mendenhall WM (2013) Radiation therapy for mucosal melanoma of the head and neck. Am J Clin Oncol [Epub ahead of print]
6.
Zurück zum Zitat Gal TJ, Silver N, Huang B (2011) Demographics and treatment trends in sinonasal mucosal melanoma. Laryngoscope 121(9):2026–2033PubMed Gal TJ, Silver N, Huang B (2011) Demographics and treatment trends in sinonasal mucosal melanoma. Laryngoscope 121(9):2026–2033PubMed
7.
Zurück zum Zitat Huang SF, Liao CT, Kan CR, Chen IH (2007) Primary mucosal melanoma of the nasal cavity and paranasal sinuses: 12 years of experience. J Otolaryngol 36(2):124–129PubMedCrossRef Huang SF, Liao CT, Kan CR, Chen IH (2007) Primary mucosal melanoma of the nasal cavity and paranasal sinuses: 12 years of experience. J Otolaryngol 36(2):124–129PubMedCrossRef
8.
Zurück zum Zitat Lund VJ, Chisholm EJ, Howard DJ, Wei WI (2012) Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection. Rhinology 50(2):203–210PubMed Lund VJ, Chisholm EJ, Howard DJ, Wei WI (2012) Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection. Rhinology 50(2):203–210PubMed
9.
Zurück zum Zitat Roth TN, Gengler C, Huber GF, Holzmann D (2010) Outcome of sinonasal melanoma: clinical experience and review of the literature. Head Neck 32(10):1385–1392PubMedCrossRef Roth TN, Gengler C, Huber GF, Holzmann D (2010) Outcome of sinonasal melanoma: clinical experience and review of the literature. Head Neck 32(10):1385–1392PubMedCrossRef
10.
Zurück zum Zitat Thompson LD, Wieneke JA, Miettinen M (2003) Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol 27(5):594–611PubMedCrossRef Thompson LD, Wieneke JA, Miettinen M (2003) Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol 27(5):594–611PubMedCrossRef
11.
Zurück zum Zitat Lund V, Stammberger H, Nicolai P, Castelnuovo P (2010) European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 22:1–143PubMed Lund V, Stammberger H, Nicolai P, Castelnuovo P (2010) European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 22:1–143PubMed
12.
Zurück zum Zitat Wada H, Nemoto K, Ogawa Y, Hareyama M, Yoshida H, Takamura A et al (2004) A multi-institutional retrospective analysis of external radiotherapy for mucosal melanoma of the head and neck in Northern Japan. Int J Radiat Oncol Biol Phys 59(2):495–500PubMedCrossRef Wada H, Nemoto K, Ogawa Y, Hareyama M, Yoshida H, Takamura A et al (2004) A multi-institutional retrospective analysis of external radiotherapy for mucosal melanoma of the head and neck in Northern Japan. Int J Radiat Oncol Biol Phys 59(2):495–500PubMedCrossRef
13.
Zurück zum Zitat Moreno MA, Roberts DB, Kupferman ME, DeMonte F, El-Naggar AK, Williams M, Rosenthal DS, Hanna EY (2010) Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer 116(9):2215–2223PubMed Moreno MA, Roberts DB, Kupferman ME, DeMonte F, El-Naggar AK, Williams M, Rosenthal DS, Hanna EY (2010) Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer 116(9):2215–2223PubMed
14.
Zurück zum Zitat Clifton N, Harrison L, Bradley PJ, Jones NS (2011) Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review. J Laryngol Otol 125(5):479–485PubMedCrossRef Clifton N, Harrison L, Bradley PJ, Jones NS (2011) Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review. J Laryngol Otol 125(5):479–485PubMedCrossRef
15.
Zurück zum Zitat Temam S, Mamelle G, Marandas P, Wibault P, Avril MF, Janot F et al (2005) Postoperative radiotherapy for primary mucosal melanoma of the head and neck. Cancer 103(2):313–319PubMedCrossRef Temam S, Mamelle G, Marandas P, Wibault P, Avril MF, Janot F et al (2005) Postoperative radiotherapy for primary mucosal melanoma of the head and neck. Cancer 103(2):313–319PubMedCrossRef
16.
Zurück zum Zitat Dzepina D, Kalogjera L, Baudoin T (2012) Recurrent sinonasal melanoma—report of five surgical cases and short literature review. Coll Antropol 36(Suppl 2):179–184PubMed Dzepina D, Kalogjera L, Baudoin T (2012) Recurrent sinonasal melanoma—report of five surgical cases and short literature review. Coll Antropol 36(Suppl 2):179–184PubMed
17.
Zurück zum Zitat Lund V, Howard DJ, Wei WI (2007) Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 21(1):89–94PubMedCrossRef Lund V, Howard DJ, Wei WI (2007) Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 21(1):89–94PubMedCrossRef
18.
Zurück zum Zitat Nicolai P, Battaglia P, Bignami M, Bolzoni VA, Delu G, Khrais T et al (2008) Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10 year experience. Am J Rhinol 22(3):308–316PubMedCrossRef Nicolai P, Battaglia P, Bignami M, Bolzoni VA, Delu G, Khrais T et al (2008) Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10 year experience. Am J Rhinol 22(3):308–316PubMedCrossRef
19.
Zurück zum Zitat Martin JM, Porceddu S, Weih L, Corry, Peters LJ (2004) Outcomes in sinonasal mucosal melanoma. ANZ J Surg 74(10):838–842PubMedCrossRef Martin JM, Porceddu S, Weih L, Corry, Peters LJ (2004) Outcomes in sinonasal mucosal melanoma. ANZ J Surg 74(10):838–842PubMedCrossRef
20.
Zurück zum Zitat Dauer EH, Lewis JE, Rohlinger AL, Weaver AL, Olsen KD (2008) Sinonasal melanoma: a clinicopathologic review of 61 cases. Otolaryngol Head Neck Surg 138(3):347–352PubMedCrossRef Dauer EH, Lewis JE, Rohlinger AL, Weaver AL, Olsen KD (2008) Sinonasal melanoma: a clinicopathologic review of 61 cases. Otolaryngol Head Neck Surg 138(3):347–352PubMedCrossRef
21.
Zurück zum Zitat Krengli M, Masini L, Kaanders JH, Maingon P, Oei SB, Zouhair A et al (2006) Radiotherapy in the treatment of mucosal melanoma of the upper aero digestive tract: analysis of 74 cases. A rare cancer network study. Int J Radiat Oncol Biol Phys 65(3):751–759PubMedCrossRef Krengli M, Masini L, Kaanders JH, Maingon P, Oei SB, Zouhair A et al (2006) Radiotherapy in the treatment of mucosal melanoma of the upper aero digestive tract: analysis of 74 cases. A rare cancer network study. Int J Radiat Oncol Biol Phys 65(3):751–759PubMedCrossRef
22.
Zurück zum Zitat Owens JM, Roberts DB, Myers JN (2003) The role of postoperative adjuvant radiation therapy in the treatment of mucosal melanomas of the head and neck region. Arch Otolaryngol Head Neck Surg 129(8):864–868PubMedCrossRef Owens JM, Roberts DB, Myers JN (2003) The role of postoperative adjuvant radiation therapy in the treatment of mucosal melanomas of the head and neck region. Arch Otolaryngol Head Neck Surg 129(8):864–868PubMedCrossRef
23.
Zurück zum Zitat Lund VJ, Howard DJ, Harding L, Wei WI (1999) Management options and survival in malignant melanoma of the sinonasal mucosa. Laryngoscope 109(2 Pt 1):208–211PubMedCrossRef Lund VJ, Howard DJ, Harding L, Wei WI (1999) Management options and survival in malignant melanoma of the sinonasal mucosa. Laryngoscope 109(2 Pt 1):208–211PubMedCrossRef
24.
Zurück zum Zitat Nandapalan V, Roland NJ, Helliwell TR, Williams EM, Hamilton JW, Jones AS (1998) Mucosal melanoma of the head and neck. Clin Otolaryngol Allied Sci 23(2):107–116PubMedCrossRef Nandapalan V, Roland NJ, Helliwell TR, Williams EM, Hamilton JW, Jones AS (1998) Mucosal melanoma of the head and neck. Clin Otolaryngol Allied Sci 23(2):107–116PubMedCrossRef
25.
Zurück zum Zitat Patel SG, Prasad ML, Escrig M, Singh B, Shaha AR, Kraus DH et al (2002) Primary mucosal malignant melanoma of the head and neck. Head Neck 24(3):247–257PubMedCrossRef Patel SG, Prasad ML, Escrig M, Singh B, Shaha AR, Kraus DH et al (2002) Primary mucosal malignant melanoma of the head and neck. Head Neck 24(3):247–257PubMedCrossRef
Metadaten
Titel
Surgical management of recurrent sinonasal mucosal melanoma: endoscopic or transfacial resection
verfasst von
G. J. Ledderose
A. Leunig
Publikationsdatum
01.02.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 2/2015
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-014-3119-y

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