nach oben

European Journal of Applied Physiology

Erschienen in:

23.04.2018 | Original Article

Muscle quality characteristics of muscles in the thigh, upper arm and lower back in elderly men and women

verfasst von: Akito Yoshiko, Takashi Kaji, Hiroki Sugiyama, Teruhiko Koike, Yoshiharu Oshida, Hiroshi Akima

Erschienen in: European Journal of Applied Physiology | Ausgabe 7/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The ratio of fat within skeletal muscle is an important parameter that is indicative of muscle quality, and can be assessed using ultrasonography to measure echo intensity (EI). Muscle EI indicates muscle strength and risk of physical dysfunction; however, this observation was determined following examinations of only selected muscle. The purpose of this study was to investigate the EI characteristics of muscles in several regions in elderly men and women, using physical function tests and serum cholesterol levels.

Methods

Twenty-two men and women (age 78 ± 8 years) participated in this study. The EIs were calculated from rectus femoris (RF), biceps femoris (BF) triceps brachii (TB) and multifidus (MF) using B-mode transverse ultrasound images. Seven functional tests (isometric knee-extension peak torque, functional reach, sit-to-stand, 5-m normal/maximal speed walking, handgrip strength and timed up-and-go) and blood lipid components including adipocytokines were measured in all participants.

Results

A statistically significant correlation between EI of the RF, TB and BF was observed (r = 0.46–0.50, P < 0.05), but not between EI of the MF and that of other muscles. EI of muscles of the limbs, which was averaged EI for RF, TB and BF, was negatively correlated with leptin levels (adjusted R² = 0.27, P < 0.01), and EI of the MF was correlated with muscle mass and performance in the timed up-and-go test (adjusted R² = 0.61, P < 0.01).

Conclusion

These results suggest that EI might be influenced by specific parameters depending on the location of the muscle.

Addison O, Marcus RL, Lastayo PC, Ryan AS (2014) Intermuscular fat: a review of the consequences and causes. Int J Endocrinol 2014:309570. https://doi.org/10.1155/2014/309570 CrossRefPubMedPubMedCentral

Akima H, Kano Y, Enomoto Y, Ishizu M, Okada M, Oishi Y, Katsuta S, Kuno S (2001) Muscle function in 164 men and women aged 20–84 year. Med Sci Sports Exerc 33:220–226CrossRefPubMed

Akima H, Katayama K, Sato K, Ishida K, Masuda K, Takada H, Watanabe Y, Iwase S (2005) Intensive cycle training with artificial gravity maintains muscle size during bed rest. Aviat Sp Environ Med 76(10):923–929

Akima H, Yoshiko A, Hioki M, Kanehira N, Shimaoka K, Koike T, Sakakibara H, Oshida Y (2015) Skeletal muscle size is a major predictor of intramuscular fat content regardless of age. Eur J Appl Physiol 115:1627–1635. https://doi.org/10.1007/s00421-015-3148-2 CrossRefPubMed

Akima H, Hioki M, Yoshiko A, Koike T, Sakakibara H, Takahashi H, Oshida Y (2016) Intramuscular adipose tissue determined by T1-weighted MRI at 3 T primarily reflects extramyocellular lipids. Magn Reson Imaging 34:397–403. https://doi.org/10.1016/j.mri.2015.12.038 CrossRefPubMed

Akima H, Yoshiko A, Tomita A, Ando R, Saito A, Ogawa M, Kondo S, Tanaka NI (2017) Relationship between quadriceps echo intensity and functional and morphological characteristics in older men and women. Arch Gerontol Geriatr 70:105–111. https://doi.org/10.1016/j.archger.2017.01.014 CrossRefPubMed

Anders C, Wagner H, Puta C, Grassme R, Petrovitch A, Scholle HC (2007) Trunk muscle activation patterns during walking at different speeds. J Electromyogr Kinesiol 17:245–252. https://doi.org/10.1016/j.jelekin.2006.01.002 CrossRefPubMed

Ando R, Saito A, Umemura Y, Akima H (2015) Local architecture of the vastus intermedius is a better predictor of knee extension force than that of the other quadriceps femoris muscle heads. Clin Physiol Funct Imaging 35:376–382. https://doi.org/10.1111/cpf.12173 CrossRefPubMed

Arts IM, Pillen S, Schelhaas HJ, Overeem S, Zwarts MJ (2010) Normal values for quantitative muscle ultrasonography in adults. Muscle Nerve 41:32–41. https://doi.org/10.1002/mus.21458 CrossRefPubMed

Arts IM, Schelhaas HJ, Verrijp KC, Zwarts MJ, Overeem S, van der Laak JA, Lammens MM, Pillen S (2012) Intramuscular fibrous tissue determines muscle echo intensity in amyotrophic lateral sclerosis. Muscle Nerve 45(3):449–450. https://doi.org/10.1002/mus.22254 CrossRefPubMed

Beasley LE, Koster A, Newman AB, Javaid MK, Ferrucci L, Kritchevsky SB, Kuller LH, Pahor M, Schaap LA, Visser M, Rubin SM, Goodpaster BH, Harris TB (2009) Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity 17:1062–1069. https://doi.org/10.1038/oby.2008.627 CrossRefPubMed

Binder EF, Yarasheski KE, Steger-May K, Sinacore DR, Brown M, Schechtman KB, Holloszy JO (2005) Effects of progressive resistance training on body composition in frail older adults: results of a randomized, controlled trial. J Gerontol A Biol Sci Med Sci 60:1425–1431CrossRefPubMed

Boettcher M, Machann J, Stefan N, Thamer C, Haring HU, Claussen CD, Fritsche A, Schick F (2009) Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity. J Magn Reson Imaging 29:1340–1345. https://doi.org/10.1002/jmri.21754 CrossRefPubMed

Cadore EL, Izquierdo M, Conceição M, Radaelli R, Pinto RS, Baroni BM, Vaz MA, Alberton CL, Pinto SS, Cunha G, Bottaro M, Kruel LFM (2012) Echo intensity is associated with skeletal muscle power and cardiovascular performance in elderly men. Exp Gerontol 47:473–478. https://doi.org/10.1016/j.exger.2012.04.002 CrossRefPubMed

Cadore EL, Casas-Herrero A, Zambom-Ferraresi F, Idoate F, Millor N, Gomez M, Rodriguez-Manas L, Izquierdo M (2014) Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians. Age (Dordrecht) 36:773–785. https://doi.org/10.1007/s11357-013-9586-z CrossRef

Caresio C, Molinari F, Emanuel G, Minetto MA (2015) Muscle echo intensity: reliability and conditioning factors. Clin Physiol Funct Imaging 35:393–403. https://doi.org/10.1111/cpf.12175 CrossRefPubMed

Crane JD, Devries MC, Safdar A, Hamadeh MJ, Tarnopolsky MA (2010) The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure. J Gerontol A Biol Sci Med Sci 65:119–128. https://doi.org/10.1093/gerona/glp179 CrossRefPubMed

Evans WJ, Campbell WW (1993) Sarcopenia and age-related changes in body composition and functional capacity. J Nutr 123:465–468CrossRefPubMed

Franz JR, Kram R (2012) The effects of grade and speed on leg muscle activations during walking. Gait Posture 35:143–147. https://doi.org/10.1016/j.gaitpost.2011.08.025 CrossRefPubMed

Fukumoto Y, Ikezoe T, Yamada Y, Tsukagoshi R, Nakamura M, Mori N, Kimura M, Ichihashi N (2012) Skeletal muscle quality assessed from echo intensity is associated with muscle strength of middle-aged and elderly persons. Eur J Appl Physiol 112:1519–1525. https://doi.org/10.1007/s00421-011-2099-5 CrossRefPubMed

Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE (1997) Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579–1585CrossRefPubMed

Goodpaster BH, Kelley DE, Thaete FL, He J, Ross R (2000) Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content. J Appl Physiol 89:104–110CrossRefPubMed

Goodpaster BH, Chomentowski P, Ward BK, Rossi A, Glynn NW, Delmonico MJ, Kritchevsky SB, Pahor M, Newman AB (2008) Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J Appl Physiol 105:1498–1503. https://doi.org/10.1152/japplphysiol.90425.2008 CrossRefPubMedPubMedCentral

Hioki M, Kanehira N, Koike T, Saito A, Takahashi H, Shimaoka K, Sakakibara H, Oshida Y, Akima H (2015) Associations of intramyocellular lipid in vastus lateralis and biceps femoris with blood free fatty acid and muscle strength differ between young and elderly adults. Clin Physiol Funct Imaging 36:457–463. https://doi.org/10.1111/cpf.12250 CrossRefPubMed

Isidori AM, Strollo F, More M, Caprio M, Aversa A, Moretti C, Frajese G, Riondino G, Fabbri A (2000) Leptin and aging: correlation with endocrine changes in male and female healthy adult populations of different body weights. J Clin Endocrinol Metab 85:1954–1962. https://doi.org/10.1210/jcem.85.5.6572 CrossRefPubMed

Johnson MA, Polgar J, Weightman D, Appleton D (1973) Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. J Neurol Sci 18:111–129CrossRefPubMed

Kent-Braun JA, Ng AV, Young K (2000) Skeletal muscle contractile and noncontractile components in young and older women and men. J Appl Physiol 88:662–668CrossRefPubMed

Ko SU, Hausdorff JM, Ferrucci L (2010) Age-associated differences in the gait pattern changes of older adults during fast-speed and fatigue conditions: results from the Baltimore longitudinal study of ageing. Age Ageing 39:688–694. https://doi.org/10.1093/ageing/afq113 CrossRefPubMedPubMedCentral

Lihn AS, Pedersen SB, Richelsen B (2005) Adiponectin: action, regulation and association to insulin sensitivity. Obes Rev 6:13–21. https://doi.org/10.1111/j.1467-789X.2005.00159.x CrossRefPubMed

Marcus RL, Addison O, Kidde JP, Dibble LE, Lastayo PC (2010) Skeletal muscle fat infiltration: impact of age, inactivity, and exercise. J Nutr Health Aging 14:362–366CrossRefPubMedPubMedCentral

Minokoshi Y, Kim Y-B, Peroni OD, Fryer LGD, Muller C, Carling D, Kahn BB (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415:339–343CrossRefPubMed

Nishihara K, Kawai H, Hayashi H, Naruse H, Kimura A, Gomi T, Hoshi F (2014) Frequency analysis of ultrasonic echo intensities of the skeletal muscle in elderly and young individuals. Clin Interv Aging 9:1471–1478. https://doi.org/10.2147/cia.s67820 CrossRefPubMedPubMedCentral

Overend TJ, Cunningham DA, Kramer JF, Lefcoe MS, Paterson DH (1992) Knee extensor and knee flexor strength: cross-sectional area ratios in young and elderly men. J Gerontol 47:M204–M210CrossRefPubMed

Pillen S, Arts IMP, Zwarts MJ (2008) Muscle ultrasound in neuromuscular disorders. Muscle Nerve 37(6):679–693. https://doi.org/10.1002/mus.21015 CrossRefPubMed

Pillen S, Tak RO, Zwarts MJ, Lammens MM, Verrijp KN, Arts IM, van der Laak JA, Hoogerbrugge PM, van Engelen BG, Verrips A (2009) Skeletal muscle ultrasound: correlation between fibrous tissue and echo intensity. Ultrasound Med Biol 35(3):443–446. https://doi.org/10.1016/j.ultrasmedbio.2008.09.016 CrossRefPubMed

Podsiadlo D, Richardson S (1991) The timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39:142–148CrossRefPubMed

Rech A, Radaelli R, Goltz FR, da Rosa LH, Schneider CD, Pinto RS (2014) Echo intensity is negatively associated with functional capacity in older women. Age (Dordrecht) 36:9708. https://doi.org/10.1007/s11357-014-9708-2 CrossRef

Reimers K, Reimers CD, Wagner S, Paetzke I, Pongratz DE (1993) Skeletal muscle sonography: a correlative study of echogenicity and morphology. J Ultrasound Med 12:73–77CrossRefPubMed

Rossi A, Zoico E, Goodpaster BH, Sepe A, Di Francesco V, Fantin F, Pizzini F, Corzato F, Vitali A, Micciolo R, Harris TB, Cinti S, Zamboni M (2010) Quantification of intermuscular adipose tissue in the erector spinae muscle by MRI: agreement with histological evaluation. Obesity 18:2379–2384. https://doi.org/10.1038/oby.2010.48 CrossRefPubMed

Ryan AS, Nicklas BJ (1999) Age-related changes in fat deposition in mid-thigh muscle in women: relationships with metabolic cardiovascular disease risk factors. Int J Obes Relat Metab Disord 23:126–132CrossRefPubMed

Tanaka NI, Miyatani M, Masuo Y, Fukunaga T, Kanehisa H (2007) Applicability of a segmental bioelectrical impedance analysis for predicting the whole body skeletal muscle volume. J Appl Physiol 103:1688–1695. https://doi.org/10.1152/japplphysiol.00255.2007 CrossRefPubMed

Tikkanen O, Haakana P, Pesola AJ, Hakkinen K, Rantalainen T, Havu M, Pullinen T, Finni T (2013) Muscle activity and inactivity periods during normal daily life. PloS One 8:e52228. https://doi.org/10.1371/journal.pone.0052228 CrossRefPubMedPubMedCentral

Tuttle LJ, Sinacore DR, Cade WT, Mueller MJ (2011) Lower physical activity is associated with higher intermuscular adipose tissue in people with type 2 diabetes and peripheral neuropathy. Phys Ther 91:923–930. https://doi.org/10.2522/ptj.20100329 CrossRefPubMedPubMedCentral

Weiss R, Dufour S, Groszmann A, Petersen K, Dziura J, Taksali SE, Shulman G, Caprio S (2003) Low adiponectin levels in adolescent obesity: a marker of increased intramyocellular lipid accumulation. J Clin Endocrinol Metab 88:2014–2018CrossRefPubMed

Wilhelm EN, Rech A, Minozzo F, Radaelli R, Botton CE, Pinto RS (2014) Relationship between quadriceps femoris echo intensity, muscle power, and functional capacity of older men. Age (Dordrecht) 36:9625. https://doi.org/10.1007/s11357-014-9625-4 CrossRef

Wren TA, Bluml S, Tseng-Ong L, Gilsanz V (2008) Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary study. AJR Am J Roentgenol 190:W8–W12. https://doi.org/10.2214/AJR.07.2732 CrossRefPubMed

Yoshiko A, Hioki M, Kanehira N, Shimaoka K, Koike T, Sakakibara H, Oshida Y, Akima H (2017a) Three-dimensional comparison of intramuscular fat content between young and old adults. BMC Med Imaging 17:12. https://doi.org/10.1186/s12880-017-0185-9 CrossRefPubMedPubMedCentral

Yoshiko A, Kaji T, Sugiyama H, Koike T, Oshida Y, Akima H (2017b) Effect of 12-month resistance and endurance training on quality, quantity, and function of skeletal muscle in older adults requiring long-term care. Exp Gerontol 98:230–237. https://doi.org/10.1016/j.exger.2017.08.036 CrossRefPubMed

Young HJ, Jenkins NT, Zhao Q, McCully KK (2015) Measurement of intramuscular fat by muscle echo intensity. Muscle Nerve 52:963–971. https://doi.org/10.1002/mus.24656 CrossRefPubMedPubMedCentral

Titel: Muscle quality characteristics of muscles in the thigh, upper arm and lower back in elderly men and women
verfasst von: Akito Yoshiko
Takashi Kaji
Hiroki Sugiyama
Teruhiko Koike
Yoshiharu Oshida
Hiroshi Akima
Publikationsdatum: 23.04.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Applied Physiology / Ausgabe 7/2018
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-018-3870-7

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Open Access ADHS Leitthema

Die Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung (ADHS) ist eine der häufigsten psychischen Störungen im Kindes- und Jugendalter [ 1 ]. In Deutschland beträgt die Prävalenz einer elternberichteten ADHS-Diagnose bei Kindern und Jugendlichen 4,4 % …

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Open Access Leitthema

Die Begrenzung von Schäden durch Substanzkonsum und andere abhängige Verhaltensweisen von Jugendlichen und jungen Erwachsenen ist ein wichtiges Anliegen der öffentlichen Gesundheit. Der Übergang von der Adoleszenz zum jungen Erwachsenenalter ist …

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Leitthema

In der Öffentlichkeit wird die berufliche Ausbildung oftmals unter ökonomischen Gesichtspunkten diskutiert: Mit den geburtenstarken Jahrgängen gehen erfahrene Fachkräfte in Rente und von nachfolgenden Generationen rücken zu wenige Arbeitskräfte …

Rauschtrinken in der frühen Adoleszenz

COVID-19 Leitthema

Alkohol ist in Deutschland die mit Abstand am häufigsten konsumierte psychoaktive Substanz. Mehr als 2 Drittel aller Erwachsenen im Alter von 18 bis 64 Jahren (70,5 %) hat 2021 in den letzten 30 Tagen Alkohol konsumiert [ 1 ]. Von diesen …

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 7/2018

Association of activity status and patterns with salivary cortisol: the population-based CoLaus study

Respiratory sinus arrhythmia in the immediate post-exercise period: correlation with breathing-specific heart rate

Moderately heavy exercise produces lower cardiovascular, RPE, and discomfort compared to lower load exercise with and without blood flow restriction

Asymmetrical intrapleural pressure distribution: a cause for scoliosis? A computational analysis

Association of electromyographic activation patterns with pain and functional disability in people with chronic neck pain

Neuromuscular and electromechanical properties of ultra-power athletes: the traceurs

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Rauschtrinken in der frühen Adoleszenz