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01.07.2013 | Original Article

Human middle longitudinal fascicle: variations in patterns of anatomical connections

verfasst von: N. Makris, M. G. Preti, T. Asami, P. Pelavin, B. Campbell, G. M. Papadimitriou, J. Kaiser, G. Baselli, C. F. Westin, M. E. Shenton, M. Kubicki

Erschienen in: Brain Structure and Function | Ausgabe 4/2013

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Abstract

Based on high-resolution diffusion tensor magnetic resonance imaging (DTI) tractographic analyses in 39 healthy adult subjects, we derived patterns of connections and measures of volume and biophysical parameters, such as fractional anisotropy (FA) for the human middle longitudinal fascicle (MdLF). Compared to previous studies, we found that the cortical connections of the MdLF in humans appear to go beyond the superior temporal (STG) and angular (AG) gyri, extending to the temporal pole (TP), superior parietal lobule (SPL), supramarginal gyrus, precuneus and the occipital lobe (including the cuneus and lateral occipital areas). Importantly, the MdLF showed a striking lateralized pattern with predominant connections between the TP, STG and AG on the left and TP, STG and SPL on the right hemisphere. In light of the results of the present study, and of the known functional role of the cortical areas interconnected by the MdLF, we suggested that this fiber pathway might be related to language, high order auditory association, visuospatial and attention functions.

Aja-Fernandez S, Niethammer M, Kubicki M, Shenton ME, Westin CF (2008) Restoration of DWI data using a Rician LMMSE estimator. IEEE Trans Med Imaging 27(10):1389–1403CrossRefPubMed

Alexander AL, Tsuruda JS, Parker DL (1997) Elimination of eddy current artifacts in diffusion-weighted echo-planar images: the use of bipolar gradients. Magn Reson Med 38(6):1016–1021CrossRefPubMed

Basser PJ (2004) Scaling laws for myelinated axons derived from an electrotonic core-conductor model. J Integr Neurosci 3(2):227–244CrossRefPubMed

Basser PJ, Pierpaoli C (1996) Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson Ser B 111:209–219CrossRef

Basser PJ, Mattiello J, LeBihan D (1994) MR diffusion tensor spectroscopy and imaging. Biophys J 66(1):259–267CrossRefPubMed

Bruce C, Desimone R, Gross CG (1981) Visual properties of neurons in a polysensory area in superior temporal sulcus of the macaque. J Neurophysiol 46(2):369–384PubMed

Burdach CF (1822) Baue und Leben des Gehirns. In: deer Dyk’schen Buchhandlung Leipzig

Catani M, Howard RJ, Pajevic S, Jones DK (2002) Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage 17(1):77–94CrossRefPubMed

Caviness VSJ, Makris N, Meyer J, Kennedy DN (1996) MRI-based parcellation of human neocortex: an anatomically specified method with estimate of reliability. J Cogn Neurosci 8:566–588CrossRef

De Witt Hamer PC, Moritz-Gasser S, Gatignol P, Duffau H (2011) Is the human left middle longitudinal fascicle essential for language? A brain electrostimulation study. Hum Brain Mapp 32(6):962–973CrossRefPubMed

Dejerine J (1895) Anatomie des Centres Nerveux. Tome 1. Rueff et Cie Paris, France

Ding SL, Van Hoesen GW, Cassell MD, Poremba A (2009) Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers. J Comp Neurol 514(6):595–623CrossRefPubMed

Duffy FH, Burchfiel JL (1971) Somatosensory system: organizational hierarchy from single units in monkey area 5. Science 172(3980):273–275CrossRefPubMed

Eccles J (1989) Evolution of the brain: creation of the self. Routledge, London

Evans AC, Collins DL, Mills SR, Brown ED, Kelly RL, Peters TM (1993) 3D statistical neuroanatomical model from 305 MRI volumes. Nuclear Science Symposium and Medical Imaging Conference, 1993 IEEE Conference Record, vol 3, pp 1813–1817

Filipek PA, Richelme C, Kennedy DN, Caviness VS Jr (1994) The young adult human brain: an MRI-based morphometric analysis. Cereb Cortex 4:344–360CrossRefPubMed

First M, Spitzer R, Gibbon M, Williams J (1997) Structured clinical interview for DSM-IV Axis I disorders. American Psychiatric Press, Washington, DC

Fitzsimmons J, Kubicki M, Smith K, Bushell G, Estepar RS, Westin CF, Nestor PG, Niznikiewicz MA, Kikinis R, McCarley RW, Shenton ME (2009) Diffusion tractography of the fornix in schizophrenia. Schizophr Res 107(1):39–46CrossRefPubMed

Flechsig P (1901) Developmental (myelogenetic) localization of the cerebral cortex in the human subject. Lancet 2:1027CrossRef

Galaburda AM, Corsiglia J, Rosen GD, Sherman GF (1987) Planum temporale asymmetry, reappraisal since Geschwind and Levitsky. Neuropsychologia 25(6):853–868CrossRef

Geschwind N, Galaburda AM (1987) Cerebral lateralization: biological mechanisms, associations and pathology. MIT Press, Cambridge

Geschwind N, Levitsky W (1968) Human brain: left-right asymmetries in temporal speech region. Science 161(3837):186–187CrossRefPubMed

Heid O (2000). Eddy current-nulled diffusion weighted. In: Proceedings, International Society of Magnetic Resonance in Medicine. Denver, Denver

Heilman KM, Van Den Abell T (1980) Right hemisphere dominance for attention: the mechanism underlying hemispheric asymmetries of inattention (neglect). Neurology 30(3):327–330CrossRefPubMed

Hickok G (2001) Functional anatomy of speech perception and speech production: psycholinguistic implications. J Psycholinguist Res 30(3):225–235CrossRefPubMed

Hickok G, Poeppel D (2000) Towards a functional neuroanatomy of speech perception. Trends Cogn Sci 4(4):131–138CrossRefPubMed

Hickok G, Poeppel D (2007) The cortical organization of speech processing. Nat Rev Neurosci 8(5):393–402CrossRefPubMed

Jones DK, Catani M, Pierpaoli C, Reeves SJ, Shergill SS, O’Sullivan M, Golesworthy P, McGuire P, Horsfield MA, Simmons A, Williams SC, Howard RJ (2006) Age effects on diffusion tensor magnetic resonance imaging tractography measures of frontal cortex connections in schizophrenia. Hum Brain Mapp 27(3):230–238CrossRefPubMed

Klingberg T, Hedehus M, Temple E, Salz T, Gabrieli JD, Moseley ME, Poldrack RA (2000) Microstructure of temporo-parietal white matter as a basis for reading ability: evidence from diffusion tensor magnetic resonance imaging. Neuron 25(2):493–500CrossRefPubMed

Lacquaniti F, Guigon E, Bianchi L, Ferraina S, Caminiti R (1995) Representing spatial information for limb movement: role of area 5 in the monkey. Cereb Cortex 5(5):391–409CrossRefPubMed

Lori NF, Akbudak E, Shimony JS, Cull TS, Snyder AZ, Guillory RK, Conturo TE (2002) Diffusion tensor fiber tracking of human brain connectivity: acquisition methods, reliability analysis and biological results. NMR Biomed 15(7–8):494–515CrossRefPubMed

Ludwig E, Klingler J (1956) Atlas Cerebri Humani. The inner structure of the brain demonstrated on the basis of macroscopical preparations. Little Brown, Boston

Makris N, Pandya DN (2009) The extreme capsule in humans and rethinking of the language circuitry. Brain Struct Funct 213(3):343–358CrossRefPubMed

Makris N, Worth AJ, Sorensen AG, Papadimitriou GM, Wu O, Reese TG, Wedeen VJ, Davis TL, Stakes JW, Caviness VS, Kaplan E, Rosen BR, Pandya DN, Kennedy DN (1997) Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann Neurol 42(6):951–962CrossRefPubMed

Makris N, Meyer JW, Bates JF, Yeterian EH, Kennedy DN, Caviness VS (1999) MRI-Based topographic parcellation of human cerebral white matter and nuclei II. Rationale and applications with systematics of cerebral connectivity. Neuroimage 9(1):18–45CrossRefPubMed

Makris N, Pandya DN, Normandin JJ (2002a) Quantitative DT-MRI investigations of the human cingulum bundle. CNS Spectr 7(7):522–528

Makris N, Papadimitriou GM, Worth AJ, Jenkins BG, Garrido L, Sorensen AG, Wedeen V, Tuch DS, Wu O, Cudkowicz ME, Caviness VS, Jr, Rosen B, Kennedy DN (2002b) Diffusion tensor imaging. In: Nemeroff C (ed) Neuropsychopharmacology: the fifth generation of progress, vol 3, Chap. 27. Lippincott, Williams, and Wilkins, New York

Makris N, Kennedy DN, McInerney S, Sorensen AG, Wang R, Caviness VS Jr, Pandya DN (2005) Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex 15(6):854–869CrossRefPubMed

Makris N, Papadimitriou GM, Sorg S, Kennedy DN, Caviness VS, Pandya DN (2007) The occipitofrontal fascicle in humans: a quantitative, in vivo, DT-MRI study. Neuroimage 37(4):1100–1111CrossRefPubMed

Makris N, Papadimitriou GM, Kaiser JR, Sorg S, Kennedy DN, Pandya DN (2009) Delineation of the middle longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex 19(4):777–785CrossRefPubMed

Makris N, Seidman LJ, Ahern T, Kennedy DN, Caviness VS, Tsuang MT, Goldstein JM (2010) White matter volume abnormalities and associations with symptomatology in schizophrenia. Psychiatry Res 183(1):21–29CrossRefPubMed

Molholm S, Sehatpour P, Mehta AD, Shpaner M, Gomez-Ramirez M, Ortigue S, Dyke JP, Schwartz TH, Foxe JJ (2006) Audio-visual multisensory integration in superior parietal lobule revealed by human intracranial recordings. J Neurophysiol 96(2):721–729CrossRefPubMed

Mori S (2002) Two and three-dimensional analyses of brain white matter architecture using diffusion imaging. CNS Spectr 7(7):529–534

Mori S, Crain BJ, Chacko VP, van Zijl PC (1999) Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 45(2):265–269CrossRefPubMed

Mountcastle VB, Lynch JC, Georgopoulos A, Sakata H, Acuna C (1975) Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space. J Neurophysiol 38(4):871–908PubMed

Nucifora PG, Verma R, Melhem ER, Gur RE, Gur RC (2005) Leftward asymmetry in relative fiber density of the arcuate fasciculus. NeuroReport 16(8):791–794CrossRefPubMed

Oh JS, Kubicki M, Rosenberger G, Bouix S, Levitt JJ, McCarley RW, Westin CF, Shenton ME (2009) Thalamo-frontal white matter alterations in chronic schizophrenia: a quantitative diffusion tractography study. Hum Brain Mapp 30(11):3812–3825CrossRefPubMed

Ono M, Kubicki M, Abernathey CD (1990) Atlas of cerebral sulci. Thieme, New York

Petrides M, Pandya DN (2002) Association pathways of the prefrontal cortex and functional observations. In: Struss DT, Knight RT (eds) Principles of frontal lobe function. Oxford University Press, Oxford, pp 31–50CrossRef

Pierpaoli C, Basser PJ (1996) Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 36(6):893–906CrossRefPubMed

Poremba A, Saunders RC, Crane AM, Cook M, Sokoloff L, Mishkin M (2003) Functional mapping of the primate auditory system. Science 299(5606):568–572CrossRefPubMed

Rademacher J, Galaburda AM, Kennedy DN, Filipek PA, Caviness VSj (1992) Human cerebral cortex: localization, parcellation, and morphometry with magnetic resonance imaging. J Cogn Neurosci 4(4):352–374CrossRef

Rademacher J, Caviness VS Jr, Steinmetz H, Galaburda AM (1993) Topographical variation of the human primary cortices: implications for neuroimaging, brain mapping, and neurobiology. Cereb Cortex 3(4):313–329CrossRefPubMed

Rajarethinam R, Sahni S, Rosenberg DR, Keshavan MS (2004) Reduced superior temporal gyrus volume in young offspring of patients with schizophrenia. Am J Psychiatry 161(6):1121–1124CrossRefPubMed

Rilling JK, Glasser MF, Preuss TM, Ma X, Zhao T, Hu X, Behrens TE (2008) The evolution of the arcuate fasciculus revealed with comparative DTI. Nat Neurosci 11(4):426–428CrossRefPubMed

Rodrigo S, Naggara O, Oppenheim C, Golestani N, Poupon C, Cointepas Y, Mangin JF, Le Bihan D, Meder JF (2007) Human subinsular asymmetry studied by diffusion tensor imaging and fiber tracking. AJNR Am J Neuroradiol 28(8):1526–1531CrossRefPubMed

Rosenberger G, Kubicki M, Nestor PG, Connor E, Bushell GB, Markant D, Niznikiewicz M, Westin CF, Kikinis R, Saykin JA, McCarley RW, Shenton ME (2008) Age-related deficits in fronto-temporal connections in schizophrenia: a diffusion tensor imaging study. Schizophr Res 102(1–3):181–188CrossRefPubMed

Rubens AB, Mahowald MW, Hutton JT (1976) Asymmetry of the lateral (sylvian) fissures in man. Neurology 26(7):620–624CrossRefPubMed

Sakata H, Takaoka Y, Kawarasaki A, Shibutani H (1973) Somatosensory properties of neurons in the superior parietal cortex (area 5) of the rhesus monkey. Brain Res 64:85–102CrossRefPubMed

Sanides F (1962) Architectonics of the human frontal lobe of the brain. With a demonstration of the principles of its formation as a reflection of phylogenetic differentiation of the cerebral cortex. Monogr Gesamtgeb Neurol Psychiatr 98:1–201PubMed

Sapolsky D, Bakkour A, Negreira A, Nalipinski P, Weintraub S, Mesulam MM, Caplan D, Dickerson BC (2010) Cortical neuroanatomic correlates of symptom severity in primary progressive aphasia. Neurology 75(4):358–366CrossRefPubMed

Schmahmann JD, Pandya DN (2006) Fiber pathways of the brain. Oxford University Press, New YorkCrossRef

Schmahmann JD, Pandya DN, Wang R, Dai G, D’Arceuil HE, de Crespigny AJ, Wedeen VJ (2007) Association fibre pathways of the brain: parallel observations from diffusion spectrum imaging and autoradiography. Brain 130(Pt 3):630–653CrossRefPubMed

Seltzer B, Pandya DN (1978) Afferent cortical connections and architectonics of the superior temporal sulcus and surrounding cortex in the rhesus monkey. Brain Res 149(1):1–24CrossRefPubMed

Seltzer B, Pandya DN (1984) Further observations on parieto-temporal connections in the rhesus monkey. Exp Brain Res 55(2):301–312CrossRefPubMed

Seltzer B, Pandya DN (1991) Post-rolandic cortical projections of the superior temporal sulcus in the rhesus monkey. J Comp Neurol 312(4):625–640CrossRefPubMed

Song SK, Sun SW, Ramsbottom MJ, Chang C, Russell J, Cross AH (2002) Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 17(3):1429–1436CrossRefPubMed

Song SK, Sun SW, Ju WK, Lin SJ, Cross AH, Neufeld AH (2003) Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage 20(3):1714–1722CrossRefPubMed

Talairach J, Tournoux P (1988) Co-planar stereotaxic atlas of the human brain. Thieme, New York

Thiebaut de Schotten M, Dell’Acqua F, Forkel SJ, Simmons A, Vergani F, Murphy DG, Catani M (2011a) A lateralized brain network for visuospatial attention. Nat Neurosci 14(10):1245–1246CrossRefPubMed

Thiebaut de Schotten M, Ffytche DH, Bizzi A, Dell’Acqua F, Allin M, Walshe M, Murray R, Williams SC, Murphy DG, Catani M (2011b) Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography. Neuroimage 54(1):49–59CrossRefPubMed

Turken AU, Dronkers NF (2011) The neural architecture of the language comprehension network: converging evidence from lesion and connectivity analyses. Front Syst Neurosci 5:1CrossRefPubMed

Wang R, Benner T, Sorensen AG, Wedeen V (2007) Diffusion toolkit: a software package for diffusion imaging data processing and tractography. In: Proceedings, International Society for Magnetic Resonance in Medicine, Berlin, Germany

Titel: Human middle longitudinal fascicle: variations in patterns of anatomical connections
verfasst von: N. Makris
M. G. Preti
T. Asami
P. Pelavin
B. Campbell
G. M. Papadimitriou
J. Kaiser
G. Baselli
C. F. Westin
M. E. Shenton
M. Kubicki
Publikationsdatum: 01.07.2013
Verlag: Springer-Verlag
Erschienen in: Brain Structure and Function / Ausgabe 4/2013
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-012-0441-2

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