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Erschienen in: European Journal of Pediatrics 5/2007

01.05.2007 | Review

Prognosis of antenatally diagnosed oligohydramnios of renal origin

verfasst von: Markus J. Kemper, Dirk E. Mueller-Wiefel

Erschienen in: European Journal of Pediatrics | Ausgabe 5/2007

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Abstract

Although clinical outcome data on fetuses with oligohydramnios of renal origin are scarce, prognosis is regarded as poor due to a high risk of renal dysfunction and pulmonary hypoplasia. This review aims to summarize the current knowledge and clinical experience with patients presenting antenatally with renal oligohydramnios. By reviewing the underlying mechanisms, complications, and outcome data, we hope to further improve antenatal counseling and postnatal care. We conclude that prognosis of ROH has changed in recent years. While early data before the introduction of sophisticated neonatal intensive care and renal replacement therapy indicated a poor prognosis, nowadays, a much more optimistic prognosis of children after renal oligohydramnios can be expected from the recent publications in the literature.
Literatur
1.
Zurück zum Zitat Abe Y, Mizuno K, Horie H, Matsumoto M, Yamaoka A, Mizutani K, Takeuchi T, Iikura Y (2002) Potter sequence complicated by congenital cystic lesion of the bladder. Am J Perinatol 19(5):267–272PubMedCrossRef Abe Y, Mizuno K, Horie H, Matsumoto M, Yamaoka A, Mizutani K, Takeuchi T, Iikura Y (2002) Potter sequence complicated by congenital cystic lesion of the bladder. Am J Perinatol 19(5):267–272PubMedCrossRef
2.
Zurück zum Zitat Biard JM, Johnson MP, Carr MC, Wilson RD, Hedrick HL, Pavlock C, Adzick NS (2005) Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction. Obstet Gynecol 106(3):503–508PubMed Biard JM, Johnson MP, Carr MC, Wilson RD, Hedrick HL, Pavlock C, Adzick NS (2005) Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction. Obstet Gynecol 106(3):503–508PubMed
3.
Zurück zum Zitat Bronshtein M, Blumenfeld Z (1991) First- and early second-trimester oligohydramnios—a predictor of poor fetal outcome except in iatrogenic oligohydramnios post chorionic villus biopsy. Ultrasound Obstet Gynecol 1(4):245–249PubMedCrossRef Bronshtein M, Blumenfeld Z (1991) First- and early second-trimester oligohydramnios—a predictor of poor fetal outcome except in iatrogenic oligohydramnios post chorionic villus biopsy. Ultrasound Obstet Gynecol 1(4):245–249PubMedCrossRef
5.
Zurück zum Zitat Campbell S, Pearce JM (1983) Ultrasound visualization of congenital malformations. Br Med Bull 39(4):322–331PubMed Campbell S, Pearce JM (1983) Ultrasound visualization of congenital malformations. Br Med Bull 39(4):322–331PubMed
6.
Zurück zum Zitat Chauhan SP, Doherty DD, Magann EF, Cahanding F, Moreno F, Klausen JH (2004) Amniotic fluid index vs single deepest pocket technique during modified biophysical profile: a randomized clinical trial. Am J Obstet Gynecol 191(2):661–667; Discussion 667–668PubMedCrossRef Chauhan SP, Doherty DD, Magann EF, Cahanding F, Moreno F, Klausen JH (2004) Amniotic fluid index vs single deepest pocket technique during modified biophysical profile: a randomized clinical trial. Am J Obstet Gynecol 191(2):661–667; Discussion 667–668PubMedCrossRef
7.
Zurück zum Zitat Chevalier RL (2006) Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr 18(2):153–160PubMedCrossRef Chevalier RL (2006) Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr 18(2):153–160PubMedCrossRef
8.
Zurück zum Zitat De Carolis MP, Romagnoli C, De Santis M, Piersigilli F, Vento G, Caruso A (2004) Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion? Biol Neonate 86(4):222–229PubMedCrossRef De Carolis MP, Romagnoli C, De Santis M, Piersigilli F, Vento G, Caruso A (2004) Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion? Biol Neonate 86(4):222–229PubMedCrossRef
9.
Zurück zum Zitat Eckoldt F, Heling KS, Woderich R, Wolke S (2004) Posterior urethral valves: prenatal diagnostic signs and outcome. Urol Int 73(4):296–301PubMedCrossRef Eckoldt F, Heling KS, Woderich R, Wolke S (2004) Posterior urethral valves: prenatal diagnostic signs and outcome. Urol Int 73(4):296–301PubMedCrossRef
10.
Zurück zum Zitat El-Ghoneimi A, Desgrippes A, Luton D, Macher MA, Guibourdenche J, Garel C, Muller F, Vuillard E, Lottmann H, Nessmann C, Oury JF, Aigrain Y (1999) Outcome of posterior urethral valves: to what extent is it improved by prenatal diagnosis? J Urol 162(3 Pt 1):849–853PubMedCrossRef El-Ghoneimi A, Desgrippes A, Luton D, Macher MA, Guibourdenche J, Garel C, Muller F, Vuillard E, Lottmann H, Nessmann C, Oury JF, Aigrain Y (1999) Outcome of posterior urethral valves: to what extent is it improved by prenatal diagnosis? J Urol 162(3 Pt 1):849–853PubMedCrossRef
11.
Zurück zum Zitat Fischler BR, Berg UB (1994) Potter sequence and consanguinity—a case report. Pediatr Nephrol 8(1):81–82PubMedCrossRef Fischler BR, Berg UB (1994) Potter sequence and consanguinity—a case report. Pediatr Nephrol 8(1):81–82PubMedCrossRef
12.
Zurück zum Zitat Freedman AL, Johnson MP, Gonzalez R (2000) Fetal therapy for obstructive uropathy: past, present, future? Pediatr Nephrol 14(2):167–176PubMedCrossRef Freedman AL, Johnson MP, Gonzalez R (2000) Fetal therapy for obstructive uropathy: past, present, future? Pediatr Nephrol 14(2):167–176PubMedCrossRef
13.
Zurück zum Zitat Freedman AL, Johnson MP, Smith CA, Gonzalez R, Evans MI (1999) Long-term outcome in children after antenatal intervention for obstructive uropathies. Lancet 354(9176):374–377PubMedCrossRef Freedman AL, Johnson MP, Smith CA, Gonzalez R, Evans MI (1999) Long-term outcome in children after antenatal intervention for obstructive uropathies. Lancet 354(9176):374–377PubMedCrossRef
14.
Zurück zum Zitat Gloor JM, Ogburn PL Jr, Breckle RJ, Morgenstern BZ, Milliner DS (1995) Urinary tract anomalies detected by prenatal ultrasound examination at Mayo Clinic Rochester. Mayo Clin Proc 70(6):526–531PubMed Gloor JM, Ogburn PL Jr, Breckle RJ, Morgenstern BZ, Milliner DS (1995) Urinary tract anomalies detected by prenatal ultrasound examination at Mayo Clinic Rochester. Mayo Clin Proc 70(6):526–531PubMed
15.
Zurück zum Zitat Gramellini D, Fieni S, Kaihura C, Piantelli G, Verrotti C (2003) Antepartum amnioinfusion: a review. J Matern Fetal Neonatal Med 14(5):291–296PubMed Gramellini D, Fieni S, Kaihura C, Piantelli G, Verrotti C (2003) Antepartum amnioinfusion: a review. J Matern Fetal Neonatal Med 14(5):291–296PubMed
16.
Zurück zum Zitat Hadlock FP, Deter RL, Carpenter R, Gonzalez ET, Park SK (1981) Sonography of fetal urinary tract anomalies. AJR Am J Roentgenol 137(2):261–267PubMed Hadlock FP, Deter RL, Carpenter R, Gonzalez ET, Park SK (1981) Sonography of fetal urinary tract anomalies. AJR Am J Roentgenol 137(2):261–267PubMed
17.
Zurück zum Zitat Harrison MR, Golbus MS, Filly RA, Nakayama DK, Callen PW, de Lorimier AA, Hricak H (1982) Management of the fetus with congenital hydronephrosis. J Pediatr Surg 17(6):728–742PubMedCrossRef Harrison MR, Golbus MS, Filly RA, Nakayama DK, Callen PW, de Lorimier AA, Hricak H (1982) Management of the fetus with congenital hydronephrosis. J Pediatr Surg 17(6):728–742PubMedCrossRef
18.
Zurück zum Zitat Kari JA, Gonzalez C, Ledermann SE, Shaw V, Rees L (2000) Outcome and growth of infants with severe chronic renal failure. Kidney Int 57(4):1681–1687PubMedCrossRef Kari JA, Gonzalez C, Ledermann SE, Shaw V, Rees L (2000) Outcome and growth of infants with severe chronic renal failure. Kidney Int 57(4):1681–1687PubMedCrossRef
19.
Zurück zum Zitat Kemper MJ, Muller-Wiefel DE (2001) Renal function in congenital anomalies of the kidney and urinary tract. Curr Opin Urol 11(6):571–575PubMedCrossRef Kemper MJ, Muller-Wiefel DE (2001) Renal function in congenital anomalies of the kidney and urinary tract. Curr Opin Urol 11(6):571–575PubMedCrossRef
20.
Zurück zum Zitat Kemper MJ, Neuhaus TJ, Timmermann K, Hueneke B, Laube G, Harps E, Mueller-Wiefel DE (2001) Antenatal oligohydramnios of renal origin: postnatal therapeutic and prognostic challenges. Clin Nephrol 56(6):S9–S12PubMed Kemper MJ, Neuhaus TJ, Timmermann K, Hueneke B, Laube G, Harps E, Mueller-Wiefel DE (2001) Antenatal oligohydramnios of renal origin: postnatal therapeutic and prognostic challenges. Clin Nephrol 56(6):S9–S12PubMed
21.
Zurück zum Zitat Klaassen I, Neuhaus TJ, Mueller-Wiefel DE, Kemper MJ (2006) Antenatal oligohydramnios of renal origin: long-term outcome. Nephrol Dial Transplant (electronic publication 25 October 2006) Klaassen I, Neuhaus TJ, Mueller-Wiefel DE, Kemper MJ (2006) Antenatal oligohydramnios of renal origin: long-term outcome. Nephrol Dial Transplant (electronic publication 25 October 2006)
22.
Zurück zum Zitat Kuwayama F, Miyazaki Y, Ichikawa I (2002) Embryogenesis of the congenital anomalies of the kidney and the urinary tract. Nephrol Dial Transplant 17(Suppl 9):45–47PubMedCrossRef Kuwayama F, Miyazaki Y, Ichikawa I (2002) Embryogenesis of the congenital anomalies of the kidney and the urinary tract. Nephrol Dial Transplant 17(Suppl 9):45–47PubMedCrossRef
23.
Zurück zum Zitat Lam BC, Wong SN, Yeung CY, Tang MH, Ghosh A (1993) Outcome and management of babies with prenatal ultrasonographic renal abnormalities. Am J Perinatol 10(4):263–268PubMedCrossRef Lam BC, Wong SN, Yeung CY, Tang MH, Ghosh A (1993) Outcome and management of babies with prenatal ultrasonographic renal abnormalities. Am J Perinatol 10(4):263–268PubMedCrossRef
24.
Zurück zum Zitat Ledermann SE, Scanes ME, Fernando ON, Duffy PG, Madden SJ, Trompeter RS (2000) Long-term outcome of peritoneal dialysis in infants. J Pediatr 136(1):24–29PubMedCrossRef Ledermann SE, Scanes ME, Fernando ON, Duffy PG, Madden SJ, Trompeter RS (2000) Long-term outcome of peritoneal dialysis in infants. J Pediatr 136(1):24–29PubMedCrossRef
25.
Zurück zum Zitat Magann EF, Isler CM, Chauhan SP, Martin JN Jr (2000) Amniotic fluid volume estimation and the biophysical profile: a confusion of criteria. Obstet Gynecol 96(4):640–642PubMedCrossRef Magann EF, Isler CM, Chauhan SP, Martin JN Jr (2000) Amniotic fluid volume estimation and the biophysical profile: a confusion of criteria. Obstet Gynecol 96(4):640–642PubMedCrossRef
26.
Zurück zum Zitat Miguelez J, Bunduki V, Yoshizaki CT, Sadek Ldos S, Koch V, Peralta CF, Zugaib M (2006) Fetal obstructive uropathy: is urine sampling useful for prenatal counselling? Prenat Diagn 26(1):81–84PubMedCrossRef Miguelez J, Bunduki V, Yoshizaki CT, Sadek Ldos S, Koch V, Peralta CF, Zugaib M (2006) Fetal obstructive uropathy: is urine sampling useful for prenatal counselling? Prenat Diagn 26(1):81–84PubMedCrossRef
27.
Zurück zum Zitat Muller F, Dreux S, Audibert F, Chabaud JJ, Rousseau T, D’Herve D, Dumez Y, Ngo S, Gubler MC, Dommergues M (2004) Fetal serum ss2-microglobulin and cystatin C in the prediction of post-natal renal function in bilateral hypoplasia and hyperechogenic enlarged kidneys. Prenat Diagn 24(5):327–332PubMedCrossRef Muller F, Dreux S, Audibert F, Chabaud JJ, Rousseau T, D’Herve D, Dumez Y, Ngo S, Gubler MC, Dommergues M (2004) Fetal serum ss2-microglobulin and cystatin C in the prediction of post-natal renal function in bilateral hypoplasia and hyperechogenic enlarged kidneys. Prenat Diagn 24(5):327–332PubMedCrossRef
28.
Zurück zum Zitat Nakayama DK, Harrison MR, de Lorimier AA (1986) Prognosis of posterior urethral valves presenting at birth. J Pediatr Surg 21(1):43–45PubMed Nakayama DK, Harrison MR, de Lorimier AA (1986) Prognosis of posterior urethral valves presenting at birth. J Pediatr Surg 21(1):43–45PubMed
29.
Zurück zum Zitat Ott WJ (2005) Reevaluation of the relationship between amniotic fluid volume and perinatal outcome. Am J Obstet Gynecol 192(6):1803–1809; Discussion 1809PubMedCrossRef Ott WJ (2005) Reevaluation of the relationship between amniotic fluid volume and perinatal outcome. Am J Obstet Gynecol 192(6):1803–1809; Discussion 1809PubMedCrossRef
30.
Zurück zum Zitat Podevin G, Mandelbrot L, Vuillard E, Oury JF, Aigrain Y (1996) Outcome of urological abnormalities prenatally diagnosed by ultrasound. Fetal Diagn Ther 11(3):181–190PubMedCrossRef Podevin G, Mandelbrot L, Vuillard E, Oury JF, Aigrain Y (1996) Outcome of urological abnormalities prenatally diagnosed by ultrasound. Fetal Diagn Ther 11(3):181–190PubMedCrossRef
31.
Zurück zum Zitat Rani R, Cameron A, Munro F (1997) Prenatal diagnosis and management of urethral obstruction. J Obstet Gynaecol Res 23(1):59–62PubMed Rani R, Cameron A, Munro F (1997) Prenatal diagnosis and management of urethral obstruction. J Obstet Gynaecol Res 23(1):59–62PubMed
32.
Zurück zum Zitat Robyr R, Benachi A, Daikha-Dahmane F, Martinovich J, Dumez Y, Ville Y (2005) Correlation between ultrasound and anatomical findings in fetuses with lower urinary tract obstruction in the first half of pregnancy. Ultrasound Obstet Gynecol 25(5):478–482PubMedCrossRef Robyr R, Benachi A, Daikha-Dahmane F, Martinovich J, Dumez Y, Ville Y (2005) Correlation between ultrasound and anatomical findings in fetuses with lower urinary tract obstruction in the first half of pregnancy. Ultrasound Obstet Gynecol 25(5):478–482PubMedCrossRef
33.
Zurück zum Zitat Ross MG, Brace RA, National Institute of Child Health and Development Workshop Participants (2001) National Institute of Child Health and Development Conference summary: amniotic fluid biology—basic and clinical aspects. J Matern Fetal Med 10(1):2–19PubMed Ross MG, Brace RA, National Institute of Child Health and Development Workshop Participants (2001) National Institute of Child Health and Development Conference summary: amniotic fluid biology—basic and clinical aspects. J Matern Fetal Med 10(1):2–19PubMed
34.
Zurück zum Zitat Shroff R, Rees L, Trompeter R, Hutchinson C, Ledermann S (2006) Long-term outcome of chronic dialysis in children. Pediatr Nephrol 21(2):257–264PubMedCrossRef Shroff R, Rees L, Trompeter R, Hutchinson C, Ledermann S (2006) Long-term outcome of chronic dialysis in children. Pediatr Nephrol 21(2):257–264PubMedCrossRef
35.
Zurück zum Zitat Smith NP, Losty PD, Connell MG, Mayer U, Jesudason EC (2006) Abnormal lung development precedes oligohydramnios in a transgenic murine model of renal dysgenesis. J Urol 175(2):783–786PubMedCrossRef Smith NP, Losty PD, Connell MG, Mayer U, Jesudason EC (2006) Abnormal lung development precedes oligohydramnios in a transgenic murine model of renal dysgenesis. J Urol 175(2):783–786PubMedCrossRef
36.
Zurück zum Zitat Stoll C, Alembik Y, Roth MP, Dott B (1998) Study of 224 cases of oligohydramnios and congenital malformations in a series of 225,669 consecutive births. Community Genet 1(2):71–77PubMedCrossRef Stoll C, Alembik Y, Roth MP, Dott B (1998) Study of 224 cases of oligohydramnios and congenital malformations in a series of 225,669 consecutive births. Community Genet 1(2):71–77PubMedCrossRef
37.
Zurück zum Zitat Uga N, Ishii T, Kawase Y, Arai H, Tada H (2004) Nitric oxide inhalation therapy in very low-birthweight infants with hypoplastic lung due to oligohydramnios. Pediatr Int 46(1):10–14PubMedCrossRef Uga N, Ishii T, Kawase Y, Arai H, Tada H (2004) Nitric oxide inhalation therapy in very low-birthweight infants with hypoplastic lung due to oligohydramnios. Pediatr Int 46(1):10–14PubMedCrossRef
38.
Zurück zum Zitat Van Dyck M, Bilem N, Proesmans W (1999) Conservative treatment for chronic renal failure from birth: a 3-year follow-up study. Pediatr Nephrol 13(9):865–869PubMedCrossRef Van Dyck M, Bilem N, Proesmans W (1999) Conservative treatment for chronic renal failure from birth: a 3-year follow-up study. Pediatr Nephrol 13(9):865–869PubMedCrossRef
39.
Zurück zum Zitat Zaccara A, Giorlandino C, Mobili L, Brizzi C, Bilancioni E, Capolupo I, Capitanucci ML, De Gennaro M (2005) Amniotic fluid index and fetal bladder outlet obstruction. Do we really need more? J Urol 174(4 Pt 2):1657–1660PubMedCrossRef Zaccara A, Giorlandino C, Mobili L, Brizzi C, Bilancioni E, Capolupo I, Capitanucci ML, De Gennaro M (2005) Amniotic fluid index and fetal bladder outlet obstruction. Do we really need more? J Urol 174(4 Pt 2):1657–1660PubMedCrossRef
40.
Zurück zum Zitat Zaretsky M, Ramus R, McIntire D, Magee K, Twickler DM (2005) MRI calculation of lung volumes to predict outcome in fetuses with genitourinary abnormalities. AJR Am J Roentgenol 185(5):1328–1334PubMedCrossRef Zaretsky M, Ramus R, McIntire D, Magee K, Twickler DM (2005) MRI calculation of lung volumes to predict outcome in fetuses with genitourinary abnormalities. AJR Am J Roentgenol 185(5):1328–1334PubMedCrossRef
Metadaten
Titel
Prognosis of antenatally diagnosed oligohydramnios of renal origin
verfasst von
Markus J. Kemper
Dirk E. Mueller-Wiefel
Publikationsdatum
01.05.2007
Verlag
Springer-Verlag
Erschienen in
European Journal of Pediatrics / Ausgabe 5/2007
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-006-0368-9

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