nach oben

Erschienen in:

01.06.2011 | Original Paper

Comparison of several anthropometric indices with insulin resistance proxy measures among European adolescents: The Helena Study

verfasst von: Katerina Kondaki, Evangelia Grammatikaki, David Jiménez Pavón, Yannis Manios, Marcela González-Gross, Michael Sjöstrom, Frédéric Gottrand, Dénes Molnar, Luis A. Moreno, Anthony Kafatos, Chantal Gilbert, Mathilde Kersting, Stefaan De Henauw

Erschienen in: European Journal of Pediatrics | Ausgabe 6/2011

Einloggen, um Zugang zu erhalten

Abstract

The aim of the current study was to compare the association of several anthropometric indices, with insulin resistance (IR) proxy measures in European adolescents. The present study comprises 1,097 adolescents aged 12.5–17.5 from ten European cities participating in the HELENA study. Weight, height, waist circumference (WC) and hip circumference, skinfolds thickness, fat mass (FM), fasting plasma glucose (G _F) and serum insulin (I _F) levels were measured. HOMA (as indicator of IR body mass index (BMI), waist to hip ratio (WHR) and waist to height ratio (WHtR) were calculated. I _F and HOMA were statistically significantly related to BMI, WC, skinfold sum, WHtR, WHR and FM. BMI, WC, WHtR, skinfold sum and FM displayed similar correlation with I _F and HOMA as opposed to WHR where lower correlation with IR indices was detected in the overall sample. Similar results were found for boys, girls and underweight/normal weight adolescents. On the other hand, WC and WHtR were found to be more strongly associated with IR proxy measures compared to the rest of anthropometric indices among overweight/obese subjects. Based on the current findings, WC and WHtR could be used, alternatively, to identify the overweight/obese adolescent at risk for developing IR. In addition, all aforementioned anthropometric indices, except WHR, could be used among the underweight/normal weight adolescents.

Nur mit Berechtigung zugänglich

Bacha F, Saad R, Gungor N et al (2003) Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors. J Clin Endocrinol Metab 88:2534–2540PubMedCrossRef

Banerji MA, Faridi N, Atluri R et al (1999) Body composition, visceral fat, leptin, and insulin resistance in Asian Indian men. J Clin Endocrinol Metab 84:137–144PubMedCrossRef

Beghin L, Castera M, Manios Y et al (2008) Quality assurance of ethical issues and regulatory aspects relating to good clinical practices in the HELENA Cross-Sectional Study. Int J Obes (Lond) 32(Suppl 5):S12–S18CrossRef

Bhardwaj S, Misra A, Khurana L et al (2008) Childhood obesity in Asian Indians: a burgeoning cause of insulin resistance, diabetes and sub-clinical inflammation. Asia Pac J Clin Nutr 17(Suppl 1):172–175PubMed

Biro G, Hulshof KF, Ovesen L et al (2002) Selection of methodology to assess food intake. Eur J Clin Nutr 56:S25–S32PubMedCrossRef

Booth ML, Chey T, Wake M et al (2003) Change in the prevalence of overweight and obesity among young Australians, 1969–1997. Am J Clin Nutr 77:29–36PubMed

Buiten C, Metzger B (2000) Childhood obesity and risk of cardiovascular disease: a review of the science. Pediatr Nurs 26:13–18PubMed

Burke V (2006) Obesity in childhood and cardiovascular risk. Clin Exp Pharmacol Physiol 33:831–837PubMedCrossRef

Can AS, Bersot TP, Gonen M (2009) Anthropometric indices and their relationship with cardiometabolic risk factors in a sample of Turkish adults. Public Health Nutr 12:538–546PubMedCrossRef

10.

Chiarelli F, Marcovecchio ML (2008) Insulin resistance and obesity in childhood. Eur J Endocrinol 159(Suppl 1):S67–S74PubMedCrossRef

11.

Cole TJ, Bellizzi MC, Flegal KM et al (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. Bmj 320:1240–1243PubMedCrossRef

12.

Di Iorgi N, Mittelman SD, Gilsanz V (2008) Differential effect of marrow adiposity and visceral and subcutaneous fat on cardiovascular risk in young, healthy adults. Int J Obes (Lond) 32:1854–1860CrossRef

13.

Fang YZ, Yang S, Wu G (2002) Free radicals, antioxidants, and nutrition. Nutrition 18:872–879PubMedCrossRef

14.

Gonzalez-Gross M, Breidenassel C, Gomez-Martinez S et al (2008) Sampling and processing of fresh blood samples within a European multicenter nutritional study: evaluation of biomarker stability during transport and storage. Int J Obes (Lond) 32:S66–S75CrossRef

15.

Gutin B, Johnson MH, Humphries MC et al (2007) Relationship of visceral adiposity to cardiovascular disease risk factors in black and white teens. Obesity (Silver Spring) 15:1029–1035CrossRef

16.

Hagstromer M, Bergman P, De Bourdeaudhuij I et al (2008) Concurrent validity of a modified version of the International Physical Activity Questionnaire (IPAQ-A) in European adolescents: the HELENA Study. Int J Obes (Lond) 32(Suppl 5):S42–S48CrossRef

17.

Hara M, Saitou E, Iwata F et al (2002) Waist-to-height ratio is the best predictor of cardiovascular disease risk factors in Japanese schoolchildren. J Atheroscler Thromb 9:127–132PubMed

18.

Hirschler V, Ruiz A, Romero T et al (2009) Comparison of different anthropometric indices for identifying insulin resistance in schoolchildren. Diabetes Technol Ther 11:615–621PubMedCrossRef

19.

Janssen I, Katzmarzyk PT, Ross R (2004) Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr 79:379–384PubMed

20.

Kahn HS, Imperatore G, Cheng YJ (2005) A population-based comparison of BMI percentiles and waist-to-height ratio for identifying cardiovascular risk in youth. J Pediatr 146:482–488PubMedCrossRef

21.

Kersting M, Sichert-Hellert W, Vereecken CA et al (2008) Food and nutrient intake, nutritional knowledge and diet-related attitudes in European adolescents. Int J Obes (Lond) 32(Suppl 5):S35–S41CrossRef

22.

Krekoukia M, Nassis GP, Psarra G et al (2007) Elevated total and central adiposity and low physical activity are associated with insulin resistance in children. Metabolism 56:206–213PubMedCrossRef

23.

Lohman TG, Roche AF, Martorell R (1988) Anthropometric standardization reference manual. Human Kinetics Books, Champaign

24.

Lopatynski J, Mardarowicz G, Szczesniak G (2003) A comparative evaluation of waist circumference, waist-to-hip ratio, waist-to-height ratio and body mass index as indicators of impaired glucose tolerance and as risk factors for type-2 diabetes mellitus. Ann Univ Mariae Curie Sklodowska Med 58:413–419PubMed

25.

Manios Y, Kourlaba G, Kafatos A et al (2008) Associations of several anthropometric indices with insulin resistance in children: the children study. Acta Paediatr 97:494–499PubMedCrossRef

26.

Manios Y, Moschonis G, Kourlaba G et al (2008) Prevalence and independent predictors of insulin resistance in children from Crete, Greece: the children study. Diabet Med 25:65–72PubMed

27.

Matthews DR, Hosker JP, Rudenski AS et al (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419PubMedCrossRef

28.

Mesa JL, Ortega FB, Ruiz JR et al (2006) Anthropometric determinants of a clustering of lipid-related metabolic risk factors in overweight and non-overweight adolescents—influence of cardiorespiratory fitness. The Avena study. Ann Nutr Metab 50:519–527PubMedCrossRef

29.

Misra A, Madhavan M, Vikram NK et al (2006) Simple anthropometric measures identify fasting hyperinsulinemia and clustering of cardiovascular risk factors in Asian Indian adolescents. Metabolism 55:1569–1573PubMedCrossRef

30.

Moreno LA, De Henauw S, Gonzalez-Gross M et al (2008) Design and implementation of the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study. Int J Obes (Lond) 32(Suppl 5):S4–S11CrossRef

31.

Nagy E, Vicente-Rodriguez G, Manios Y et al (2008) Harmonization process and reliability assessment of anthropometric measurements in a multicenter study in adolescents. Int J Obes (Lond) 32(Suppl 5):S58–S65CrossRef

32.

Parikh RM, Joshi SR, Menon PS et al (2007) Index of central obesity—a novel parameter. Med Hypotheses 68:1272–1275PubMedCrossRef

33.

Raitakari OT, Juonala M, Viikari JS (2005) Obesity in childhood and vascular changes in adulthood: insights into the Cardiovascular Risk in Young Finns Study. Int J Obes (Lond) 29(Suppl 2):S101–S104CrossRef

34.

Rodriguez-Rodriguez E, Palmeros-Exsome C, Lopez-Sobaler AM, et al. Preliminary data on the association between waist circumference and insulin resistance in children without a previous diagnosis. Eur J Pediatr (in press)

35.

Savva SC, Tornaritis M, Savva ME et al (2000) Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index. Int J Obes Relat Metab Disord 24:1453–1458PubMedCrossRef

36.

Schwartz MS, Chadha A (2008) Type 2 diabetes mellitus in childhood: obesity and insulin resistance. J Am Osteopath Assoc 108:518–524PubMed

37.

Svedberg J, Bjorntorp P, Smith U et al (1990) Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes 39:570–574PubMedCrossRef

38.

Tanner JM, Whitehouse RH (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 51:170–179PubMedCrossRef

39.

Thorsdottir I, Gunnarsdottir I, Palsson GI et al (2006) Anthropometric predictors of serum fasting insulin in 9- and 15-year-old children and adolescents. Nutr Metab Cardiovasc Dis 16:263–271PubMedCrossRef

40.

Vereecken CA, Covents M, Matthys C et al (2005) Young adolescents’nutrition assessment on computer (YANA-C). Eur J Clin Nutr 59:658–667PubMedCrossRef

41.

Weiss R, Caprio S (2005) The metabolic consequences of childhood obesity. Best Pract Res Clin Endocrinol Metab 19:405–419PubMedCrossRef

42.

Yan W, Wang X, Yao H et al (2006) Waist-to-height ratio and BMI predict different cardiovascular risk factors in Chinese children. Diab Care 29:2760–2761CrossRef

43.

Yang L, Samarasinghe YP, Kane P et al (2009) Visceral adiposity is closely correlated with neck circumference and represents a significant indicator of insulin resistance in WHO grade III obesity. Clin Endocrinol (Oxf) 73(2):197–200

Titel: Comparison of several anthropometric indices with insulin resistance proxy measures among European adolescents: The Helena Study
verfasst von: Katerina Kondaki
Evangelia Grammatikaki
David Jiménez Pavón
Yannis Manios
Marcela González-Gross
Michael Sjöstrom
Frédéric Gottrand
Dénes Molnar
Luis A. Moreno
Anthony Kafatos
Chantal Gilbert
Mathilde Kersting
Stefaan De Henauw
Publikationsdatum: 01.06.2011
Verlag: Springer-Verlag
Erschienen in: European Journal of Pediatrics / Ausgabe 6/2011
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-010-1322-4

Neu im Fachgebiet Pädiatrie

Klimaschutz beginnt bei der Wahl des Inhalators

14.05.2024 Klimawandel Podcast

Auch kleine Entscheidungen im Alltag einer Praxis können einen großen Beitrag zum Klimaschutz leisten. Die neue Leitlinie zur "klimabewussten Verordnung von Inhalativa" geht mit gutem Beispiel voran, denn der Wechsel vom klimaschädlichen Dosieraerosol zum Pulverinhalator spart viele Tonnen CO₂. Leitlinienautor PD Dr. Guido Schmiemann erklärt, warum nicht nur die Umwelt, sondern auch Patientinnen und Patienten davon profitieren.

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Comparison of several anthropometric indices with insulin resistance proxy measures among European adolescents: The Helena Study

Abstract

Neu im Fachgebiet Pädiatrie

Klimaschutz beginnt bei der Wahl des Inhalators

Embryotransfer erhöht womöglich Leukämierisiko der Kinder

Darf man die Behandlung eines Neonazis ablehnen?

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

Update Pädiatrie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 6/2011

Educational paper

Discomfort in children undergoing unsedated MRI

Reply to correspondence letter by S. Özsoylu regarding our manuscript "Prevalence and risk factors for vitamin d deficiency among healthy infants and young children in Sacramento, California

Hyperintense lesions in brain MRI after exposure to a mercuric chloride-containing skin whitening cream

Cerebral hemiatrophy associated with hippocampal sclerosis following a single prolonged febrile seizure

Clinical practice

Neu im Fachgebiet Pädiatrie

Klimaschutz beginnt bei der Wahl des Inhalators

Embryotransfer erhöht womöglich Leukämierisiko der Kinder

Darf man die Behandlung eines Neonazis ablehnen?

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

Update Pädiatrie