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Erschienen in: Supportive Care in Cancer 11/2007

01.11.2007 | Original Article

Evaluation of the memorial delirium assessment scale (MDAS) for the screening of delirium by means of simulated cases by palliative care health professionals

verfasst von: Nada Fadul, Guddi Kaur, Tao Zhang, J. Lynn Palmer, Eduardo Bruera

Erschienen in: Supportive Care in Cancer | Ausgabe 11/2007

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Abstract

Background

Delirium is among the most common neuropsychiatric complications of advanced cancer. The Memorial Delirium Assessment Scale (MDAS) is a widely used and validated screening tool for delirium in cancer patients.

Objective

The purpose of this study was to assess the use of the MDAS by different palliative care health professionals after receiving formal training and a guiding manual for administration and scoring.

Materials and methods

Thirty-one palliative care health professionals received a training session on the MDAS, including description of the tool, validation, and scoring. Participants also received copies of a proposed standardized manual for completion of the MDAS. Two of the investigators presented three simulated cases to the participants, who independently completed a scoring sheet for each case. The data were then analyzed according to the cases and the profession of the operators.

Results

Thirty-one scoring sheets were analyzed (11 physicians, 12 nurses, and 8 others). A correct diagnosis was achieved by 30 (96.8%) of the 31 participants in case 1 (nondelirious, true score = 5, median = 5, range = 2–15), 28 of 31 (90.3%) in case 2 (severe mixed delirium, true score = 20, median = 18, range = 10–26), and 31 of 31 in case 3 (mild hypoactive delirium, true score = 14, median = 19, range = 13–25). Overall percentage of error was 31% for items 2, 3, and 4 (cognitive) and 45% for all other items (observational) (p < 0.001). The percentage of error did not differ between physicians and nurses and other palliative care professionals (p > 0.99).

Conclusions

Our preliminary results suggest that adequate training and a guiding manual can enhance the application of MDAS by palliative care health professionals in the teaching settings. Clinical studies to assess the utility of the MDAS as a screening tool are justified to further confirm these findings.
Literatur
1.
Zurück zum Zitat Lawlor PG, Fainsinger RL, Bruera ED (2000) Delirium at the end of life: critical issues in clinical practice and research. JAMA 284:2427–2429PubMedCrossRef Lawlor PG, Fainsinger RL, Bruera ED (2000) Delirium at the end of life: critical issues in clinical practice and research. JAMA 284:2427–2429PubMedCrossRef
2.
Zurück zum Zitat Lawlor PG, Bruera ED (2002) Delirium in patients with advanced cancer. Hematol Oncol Clin North Am 16:701–714PubMedCrossRef Lawlor PG, Bruera ED (2002) Delirium in patients with advanced cancer. Hematol Oncol Clin North Am 16:701–714PubMedCrossRef
3.
Zurück zum Zitat Bruera E, Miller L, McCallion J, Macmillan K, Krefting L, Hanson J (1992) Cognitive failure in patients with terminal cancer: a prospective study. J Pain Symptom Manage 7(4):192–195PubMedCrossRef Bruera E, Miller L, McCallion J, Macmillan K, Krefting L, Hanson J (1992) Cognitive failure in patients with terminal cancer: a prospective study. J Pain Symptom Manage 7(4):192–195PubMedCrossRef
4.
Zurück zum Zitat Pereira J, Hanson J, Bruera E (1997) The frequency and clinical course of cognitive impairment in patients with terminal cancer. Cancer 79:835–842PubMedCrossRef Pereira J, Hanson J, Bruera E (1997) The frequency and clinical course of cognitive impairment in patients with terminal cancer. Cancer 79:835–842PubMedCrossRef
5.
Zurück zum Zitat Tucker GJ (1991) DSM-IV: proposals for revision of diagnostic criteria for delirium. APA work group on organic disorders of the DSM-IV task force and major contributors. Int Psychogeriatr 3:197–208PubMedCrossRef Tucker GJ (1991) DSM-IV: proposals for revision of diagnostic criteria for delirium. APA work group on organic disorders of the DSM-IV task force and major contributors. Int Psychogeriatr 3:197–208PubMedCrossRef
6.
Zurück zum Zitat Lawlor PG, Gagnon B, Mancini IL, Pereira JL, Hanson J, Suarez-Almazor ME, Bruera ED (2000) Occurrence, causes, and outcome of delirium in patients with advanced cancer: a prospective study. Arch Intern Med 160(6):786–794PubMedCrossRef Lawlor PG, Gagnon B, Mancini IL, Pereira JL, Hanson J, Suarez-Almazor ME, Bruera ED (2000) Occurrence, causes, and outcome of delirium in patients with advanced cancer: a prospective study. Arch Intern Med 160(6):786–794PubMedCrossRef
7.
Zurück zum Zitat Bruera E, Franco JJ, Maltoni M, Watanabe S, Suarez-Almazor M (1995) Changing pattern of agitated impaired mental status in patients with advanced cancer: association with cognitive monitoring, hydration, and opioid rotation. J Pain Symptom Manage 10(4):287–291PubMedCrossRef Bruera E, Franco JJ, Maltoni M, Watanabe S, Suarez-Almazor M (1995) Changing pattern of agitated impaired mental status in patients with advanced cancer: association with cognitive monitoring, hydration, and opioid rotation. J Pain Symptom Manage 10(4):287–291PubMedCrossRef
8.
Zurück zum Zitat Folstein MF, Folstein SE, McHugh PR (1975) ‘Mini-Mental State’. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198PubMedCrossRef Folstein MF, Folstein SE, McHugh PR (1975) ‘Mini-Mental State’. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198PubMedCrossRef
9.
Zurück zum Zitat Trzepacz PT, Maue FR, Coffman G, van Thiel DH (1986–1987) Neuropsychiatric assessment of liver transplantation candidates: delirium and other psychiatric disorders. Int J Psychiatry Med 16:101–111CrossRef Trzepacz PT, Maue FR, Coffman G, van Thiel DH (1986–1987) Neuropsychiatric assessment of liver transplantation candidates: delirium and other psychiatric disorders. Int J Psychiatry Med 16:101–111CrossRef
10.
Zurück zum Zitat Breitbart W, Rosenfeld B, Roth A, Smith MJ, Cohen K, Passik S (1997) The memorial delirium assessment scale. J Pain Symptom Manage 13:128–137PubMedCrossRef Breitbart W, Rosenfeld B, Roth A, Smith MJ, Cohen K, Passik S (1997) The memorial delirium assessment scale. J Pain Symptom Manage 13:128–137PubMedCrossRef
11.
Zurück zum Zitat Lawlor PG, Nekolaichuk C, Gagnon B, Mancini IL, Pereira JL, Bruera ED (2000) Clinical utility, factor analysis, and further validation of the memorial delirium assessment scale in patients with advanced cancer: assessing delirium in advanced cancer. Cancer 88(12):2859–2867PubMedCrossRef Lawlor PG, Nekolaichuk C, Gagnon B, Mancini IL, Pereira JL, Bruera ED (2000) Clinical utility, factor analysis, and further validation of the memorial delirium assessment scale in patients with advanced cancer: assessing delirium in advanced cancer. Cancer 88(12):2859–2867PubMedCrossRef
12.
Zurück zum Zitat Grassi L, Caraceni A, Beltrami E, Borreani C, Zamorani M, Maltoni M, Monti M, Luzzani M, Mercadante S, De Conno F (2001) Assessing delirium in cancer patients: the Italian versions of the Delirium Rating Scale and the Memorial Delirium Assessment Scale. J Pain Symptom Manage 21(1):59–68PubMedCrossRef Grassi L, Caraceni A, Beltrami E, Borreani C, Zamorani M, Maltoni M, Monti M, Luzzani M, Mercadante S, De Conno F (2001) Assessing delirium in cancer patients: the Italian versions of the Delirium Rating Scale and the Memorial Delirium Assessment Scale. J Pain Symptom Manage 21(1):59–68PubMedCrossRef
13.
Zurück zum Zitat Matsuoka Y, Miyake Y, Arakaki H, Tanaka K, Saeki T, Yamawaki S (2001) Clinical utility and validation of the Japanese version of Memorial Delirium Assessment Scale in a psychogeriatric inpatient setting. Gen Hosp Psychiatry 23(1):36–40PubMedCrossRef Matsuoka Y, Miyake Y, Arakaki H, Tanaka K, Saeki T, Yamawaki S (2001) Clinical utility and validation of the Japanese version of Memorial Delirium Assessment Scale in a psychogeriatric inpatient setting. Gen Hosp Psychiatry 23(1):36–40PubMedCrossRef
14.
Zurück zum Zitat Breitbart W, Gibson C, Tremblay A (2002) The delirium experience: delirium recall and delirium-related distress in hospitalized patients with cancer, their spouses/caregivers, and their nurses. Psychosomatics 43(3):183–194PubMedCrossRef Breitbart W, Gibson C, Tremblay A (2002) The delirium experience: delirium recall and delirium-related distress in hospitalized patients with cancer, their spouses/caregivers, and their nurses. Psychosomatics 43(3):183–194PubMedCrossRef
15.
Zurück zum Zitat Centeno C, Sanz A, Bruera E (2004) Delirium in advanced cancer patients. Palliat Med 18(3):184–194PubMedCrossRef Centeno C, Sanz A, Bruera E (2004) Delirium in advanced cancer patients. Palliat Med 18(3):184–194PubMedCrossRef
16.
Zurück zum Zitat Gagnon P, Allard P, Masse B, DeSerres M (2000) Delirium in terminal cancer: a prospective study using daily screening, early diagnosis, and continuous monitoring. J Pain Symptom Manage 19:412–426PubMedCrossRef Gagnon P, Allard P, Masse B, DeSerres M (2000) Delirium in terminal cancer: a prospective study using daily screening, early diagnosis, and continuous monitoring. J Pain Symptom Manage 19:412–426PubMedCrossRef
17.
Zurück zum Zitat Trzepacz P, Baker R, Greenhouse J (1988) A symptom rating scale for delirium. Psychiatry Res 23:89–97PubMedCrossRef Trzepacz P, Baker R, Greenhouse J (1988) A symptom rating scale for delirium. Psychiatry Res 23:89–97PubMedCrossRef
18.
Zurück zum Zitat Morita T, Tsunoda J, Inoue S, Chihara S, Oka K (2001) Communication Capacity Scale and Agitation Distress Scale to measure the severity of delirium in terminally ill cancer patients: a validation study. Palliat Med 15:197–206PubMedCrossRef Morita T, Tsunoda J, Inoue S, Chihara S, Oka K (2001) Communication Capacity Scale and Agitation Distress Scale to measure the severity of delirium in terminally ill cancer patients: a validation study. Palliat Med 15:197–206PubMedCrossRef
19.
Zurück zum Zitat Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI (1990) Clarifying confusion: the confusion assessment method. Ann Intern Med 113:941–948PubMed Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI (1990) Clarifying confusion: the confusion assessment method. Ann Intern Med 113:941–948PubMed
20.
Zurück zum Zitat Albert MS, Levkoff SE, Reilly C, Liptzin B, Pilgrim D, Cleary PD, Evans D, Rowe JW (1990) The delirium symptom interview: an interview for the detection of delirium symptoms in hospitalized patients. J Geriatr Psychiatry Neurol 5:14–21 Albert MS, Levkoff SE, Reilly C, Liptzin B, Pilgrim D, Cleary PD, Evans D, Rowe JW (1990) The delirium symptom interview: an interview for the detection of delirium symptoms in hospitalized patients. J Geriatr Psychiatry Neurol 5:14–21
21.
Zurück zum Zitat Miller PS, Richardson JS, Jyu CA (1988) Association of low serum anticholinergic levels and cognitive impairment in elderly presurgical patients. Am J Psychiatry 145:342–345PubMed Miller PS, Richardson JS, Jyu CA (1988) Association of low serum anticholinergic levels and cognitive impairment in elderly presurgical patients. Am J Psychiatry 145:342–345PubMed
22.
Zurück zum Zitat Gaudreau JD, Gagnon P, Harel F, Tremblay A, Roy MA (2005) Fast, systematic, and continuous delirium assessment in hospitalized patients: the nursing delirium screening scale. J Pain Symptom Manage 29(4):368–375PubMedCrossRef Gaudreau JD, Gagnon P, Harel F, Tremblay A, Roy MA (2005) Fast, systematic, and continuous delirium assessment in hospitalized patients: the nursing delirium screening scale. J Pain Symptom Manage 29(4):368–375PubMedCrossRef
23.
Zurück zum Zitat Smith MJ, Breitbart WS, Platt MM (1995) A critique of instruments and methods to detect, diagnose, and rate delirium. J Pain Symptom Manage 10:35–77PubMedCrossRef Smith MJ, Breitbart WS, Platt MM (1995) A critique of instruments and methods to detect, diagnose, and rate delirium. J Pain Symptom Manage 10:35–77PubMedCrossRef
24.
Zurück zum Zitat Anthony JC, LeResche L, Niaz U, von Korff MR, Folstein MF (1982) Limits of the ‘Mini-Mental State’ as a screening test for dementia and delirium among hospital patients. Psychol Med 12(2):397–408PubMedCrossRef Anthony JC, LeResche L, Niaz U, von Korff MR, Folstein MF (1982) Limits of the ‘Mini-Mental State’ as a screening test for dementia and delirium among hospital patients. Psychol Med 12(2):397–408PubMedCrossRef
Metadaten
Titel
Evaluation of the memorial delirium assessment scale (MDAS) for the screening of delirium by means of simulated cases by palliative care health professionals
verfasst von
Nada Fadul
Guddi Kaur
Tao Zhang
J. Lynn Palmer
Eduardo Bruera
Publikationsdatum
01.11.2007
Verlag
Springer-Verlag
Erschienen in
Supportive Care in Cancer / Ausgabe 11/2007
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-007-0247-6

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