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17.04.2017 | Original Article

Effects of diet and exercise on weight-related outcomes for breast cancer survivors and their adult daughters: an analysis of the DAMES trial

verfasst von: Danielle B. Tometich, Catherine E. Mosher, Joseph G. Winger, Hoda J. Badr, Denise C. Snyder, Richard J. Sloane, Wendy Demark-Wahnefried

Erschienen in: Supportive Care in Cancer | Ausgabe 8/2017

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Abstract

Purpose

Few trials have aimed to promote diet and exercise behaviors in both cancer survivors and their family members and examine their associations with weight-related outcomes. We conducted a secondary analysis to examine associations between change in diet and exercise behaviors and weight-related outcomes for overweight breast cancer survivors and their overweight adult daughters in the Daughters And MothErS Against Breast Cancer (DAMES) randomized trial.

Methods

The DAMES trial assessed the impact of two iteratively tailored, mailed print diet and exercise interventions against standard brochures over a 12-month period. This analysis examined change in diet and exercise behaviors and weight-related variables from baseline to post-intervention for the 50 breast cancer survivors and their adult daughters randomized to the intervention arms. To reduce the potential for type II error in this pilot, p values <0.10 were considered statistically significant.

Results

For mothers, change in diet quality was uniquely related to change in BMI (β = −0.12, p = 0.082), weight (β = −0.12, p = 0.060), and waist circumference (β = −0.38, p = 0.001), whereas change in caloric intake was related to waist circumference (β = 0.21, p = 0.002). For daughters, change in caloric intake was related to change in waist circumference (β = 0.12, p = 0.055). However, change in diet quality was not associated with weight-related outcomes in daughters. Additionally, change in exercise was not associated with weight-related outcomes in mothers or daughters.

Conclusions

Findings support mail-based and other tailored interventions for weight loss in this population, with an emphasis on diet quality for breast cancer survivors and caloric intake for their adult daughters.

Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, et al (2015) SEER Cancer Statistics Review, 1975–2012, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2012/, based on November 2014 SEER data submission, posted to the SEER web site, April 2015.

Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL et al (2012) Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin 62:242–274CrossRef

Demark-Wahnefried W, Platz EA, Ligibel JA, Blair CK, Courneya KS, Meyerhardt JA et al (2012) The role of obesity in cancer survival and recurrence. Cancer Epidemiol Biomark Prev 21:1244–1259CrossRef

McPherson K, Steel C, Dixon JM (2000) ABC of breast diseases: breast cancer—epidemiology, risk factors, and genetics. BMJ 321:624–628CrossRefPubMedPubMedCentral

Colditz GA, Willett WC, Hunter DJ, Stampfer MJ, Manson JE, Hennekens CH et al (1993) Family history, age, and risk of breast cancer: prospective data from the Nurses’ health study. JAMA 270:338–343CrossRefPubMed

Chlebowski RT, Blackburn GL, Thomson CA, Nixon DW, Shapiro A, Hoy MK et al (2006) Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women’s intervention nutrition study. J Natl Cancer Inst 98:1767–1776CrossRefPubMed

Campbell KL, Foster-Schubert KE, Alfano CM, Wang CC, Wang CY, Duggan CR et al (2012) Reduced-calorie dietary weight loss, exercise, and sex hormones in postmenopausal women: randomized controlled trial. J Clin Oncol 30:2314–2326CrossRefPubMedPubMedCentral

Alhassan S, Kim S, Bersamin A, King AC, Gardner CD (2008) Dietary adherence and weight loss success among overweight women: results from the a TO Z weight loss study. Int J Obes 32:985–991CrossRef

Imayama I, Ulrich CM, Alfano CM, Wang C, Xiao L, Wener MH et al (2012) Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial. Cancer Res 72:2314–2326CrossRefPubMedPubMedCentral

10.

Rogers L, Hopkins-Price P, Vicari S, Pamenter R, Courneya KS, Markwell S et al (2009) A randomized trial to increase physical activity in breast cancer survivors. Med Sci Sports Exerc 41:935–946CrossRefPubMed

11.

Irwin ML, Alvarez-Reeves M, Cadmus L, Mierzejewski E, Mayne ST, Yu H et al (2009) Exercise improves body fat, lean mass, and bone mass in breast cancer survivors. Obesity 17:1534–1541CrossRefPubMedPubMedCentral

12.

Milne HM, Wallman KE, Gordon S, Courneya KS (2008) Effects of a combined aerobic and resistance exercise program in breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat 108:279–288CrossRefPubMed

13.

Courneya KS, Segal RJ, Mackey JR, Gelmon K, Reid RD, Friedenreich CM et al (2007) Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. J Clin Oncol 25:4396–4404CrossRefPubMed

14.

Ransdell LB, Taylor A, Oakland D, Schmidt J, Moyer-Mileur L, Shultz B (2003) Daughters and mothers exercising together: effects of home- and community-based programs. Med Sci Sports Exerc 35:286–296CrossRefPubMed

15.

Foster-Schubert KE, Alfano CM, Duggan CR, Xiao L, Campbell KL, Kong A et al (2012) Effect of diet and exercise, alone or combined, on weight and body composition in overweight-to-obese postmenopausal women. Obesity 20:1628–1638CrossRefPubMed

16.

Anderson JW, Konz EC, Frederich RC, Wood CL (2001) Long-term weight-loss maintenance: a meta-analysis of US studies. Am J Clin Nutr 74:579–584PubMed

17.

Lopez ML, Iglesias JM, del Valle MO, Comas A, Fernandez JM, de Vries H et al (2007) Impact of a primary care intervention on smoking, drinking, diet, weight, sun exposure, and work risk in families with cancer experience. Cancer Causes Control 18:525–535CrossRefPubMed

18.

Bloom JR, Stewart SL, Chang S, You M (2006) Effects of a telephone counseling intervention on sisters of young women with breast cancer. Prev Med 43:379–384CrossRefPubMed

19.

Hartman SJ, Dunsiger SI, Marcus BH (2013) A pilot study of a physical activity intervention targeted towards women at increased risk for breast cancer. Psychooncology 22:381–387PubMed

20.

Ransdell LB, Dratt J, Kennedy C, O’Neill S, DeVoe D (2001) Daughters and mothers exercising together (DAMET): a 12-week pilot project designed to improve physical self-perception and increase recreational physical activity. Women Health 33:113–129CrossRef

21.

Olvera NN, Knox B, Scherer R, Maldonado G, Sharma SV, Alastuey L et al (2008) A healthy lifestyle program for Latino daughters and mothers: the BOUNCE overview and process evaluation. Am J Health Educ 39:283–295CrossRef

22.

Arredondo EM, Morello M, Holub C, Haughton J (2014) Feasibility and preliminary findings of a church-based mother-daughter pilot study promoting physical activity among young Latinas. Fam Commun Health 37:6–18

23.

Stolley MR, Fitzgibbon ML (1997) Effects of an obesity prevention program on the eating behavior of African American mothers and daughters. Health Educ Behav 24:152–164CrossRefPubMed

24.

Demark-Wahnefried W, Jones LW, Snyder DC, Sloane RJ, Kimmick GG, Hughes DC et al (2014) Daughters and mothers against breast cancer (DAMES): main outcomes of a randomized controlled trial of weight loss in overweight mothers with breast cancer and their overweight daughters. Cancer 120:2522–2534CrossRefPubMed

25.

McBride CM, Emmons KM, Lipkus IM (2003) Understanding the potential of teachable moments: the case of smoking cessation. Health Educ Res 18:156–170CrossRefPubMed

26.

Sinicrope PS, Brockman TA, Patten CA, Frost MH, Vierkant RA, Petersen LR et al (2008) Factors associated with breast cancer prevention communication between mothers and daughters. J Women’s Health 17:1017–1023CrossRef

27.

Bandura A (1986) Social foundations of thought and action: a social cognitive theory. Prentice-Hall, Inc, Englewood Cliffs

28.

Rosenkranz RR, Bauer A, Dzewaltowski DA (2010) Mother-daughter resemblance in BMI and obesity-related behaviors. Int J Adolesc Med Health 22:477–489CrossRefPubMed

29.

Demark-Wahnefried W, Clipp EC, Lipkus IM, Lobach D, Snyder DC, Sloane R et al (2007) Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors. J Clin Oncol 25:2709–2718CrossRefPubMed

30.

Wu T, Gao X, Chen M, Van Dam RM (2009) Long-term effectiveness of diet-plus-exercise interventions vs. diet-only interventions for weight loss: a meta-analysis. Obes Rev 10:313–323CrossRefPubMed

31.

Godin G (2011) The Godin-Shephard leisure-time physical activity questionnaire. Health Fit J Can 4:18–22

32.

Godin G, Jobin J, Bouillon J (1985) Assessment of leisure time exercise behavior by self-report: a concurrent validity study. Can J Public Health 77:359–362

33.

Guenther PM, Reedy J, Krebs-Smith SM, Reeve BB (2008) Evaluation of the healthy eating index-2005. J Am Diet Assoc 108:1854–1864CrossRefPubMed

34.

Miller PE, Mitchell DC, Harala PL, Pettit JM, Smiciklas-Wright H, Hartman TJ (2011) Development and evaluation of a method for calculating the healthy eating index-2005 using the nutrition data system for research. Public Health Nutr 14:306–313CrossRefPubMed

35.

Cronbach L, Furby L (1970) How we should measure “change”: or should we? Psychol Bull 74:68–80CrossRef

36.

Kline RB (2011) Principles and practice of structural equation modeling. Guilford Press, New York

37.

Hu L, Bentler PM (1999) Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Model 6:1–55CrossRef

38.

Tukey JW (1962) The future of data analysis. Ann Math Stat 33:1–67CrossRef

39.

Van Pelt RE, Evans EM, Schechtman KB, Ehsani AA, Kohrt WM (2001) Waist circumference vs body mass index for prediction of disease risk in postmenopausal women. Int J Obes Relat Metab Disord 25:1183–1188CrossRefPubMed

40.

U.S. Department of Health and Human Services and U.S. Department of Agriculture (2015) 2015–2020 Dietary Guidelines for Americans.

41.

Demark-Wahnefried W, Peterson BL, Winer EP, Marks L, Aziz N, Marcom PK et al (2001) Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol 19:2381–2389CrossRefPubMed

42.

Suliga E, Kozieł D, Cieśla E, Rębak D, Głuszek S (2016) Factors associated with adiposity, lipid profile disorders and the metabolic syndrome occurrence in premenopausal and postmenopausal women. PLoS One 11:1–19CrossRef

43.

Pate RR, Liese AD, Dowda M (2015) Associations among physical activity, diet quality, and weight status in US adults. Med Sci Sports Exerc 47:743–750CrossRefPubMedPubMedCentral

44.

Graff-Iversen S, Anderssen SA, Holme IM, Jenum AK, Raastad T (2008) Two short questionnaires on leisure-time physical activity compared with serum lipids, anthropometric measurements and aerobic power in a suburban population from Oslo, Norway. Eur J Epidemiol 23:167–174CrossRefPubMed

45.

Del Fabbro E, Parsons H, Warneke CL, Pulivarthi K, Litton JK, Dev R et al (2012) The relationship between body composition and response to neoadjuvant chemotherapy in women with operable breast cancer. Oncologist 17:1240–1245CrossRefPubMedPubMedCentral

Titel: Effects of diet and exercise on weight-related outcomes for breast cancer survivors and their adult daughters: an analysis of the DAMES trial
verfasst von: Danielle B. Tometich
Catherine E. Mosher
Joseph G. Winger
Hoda J. Badr
Denise C. Snyder
Richard J. Sloane
Wendy Demark-Wahnefried
Publikationsdatum: 17.04.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 8/2017
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-017-3665-0

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Effects of diet and exercise on weight-related outcomes for breast cancer survivors and their adult daughters: an analysis of the DAMES trial