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Comparative Clinical Pathology

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14.04.2020 | Case Report

Pathological and molecular detection of a rare case of cutaneous cryptococcosis in a 9-year-old horse

verfasst von: Abdelmoneim Ali, Bakr Ahmed, Naif AlGabri, Mohamed Abdelmoneim, Mohamed Gomaa, Ahmed N. F. Neamat-Allah

Erschienen in: Comparative Clinical Pathology | Ausgabe 4/2020

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Abstract

This report describes a rare case of primary cutaneous cryptococcosis in equines. A young gelding horse was presented with facial masses showing ulcerations and yellowish discharge. Histopathological examination of biopsy specimens showed a dermal granulomatous reaction containing neutrophils, macrophages, and giant cells. In addition, numerous spherical yeast-like organisms were clearly observed within the granulomatous reaction. We suspected that the observed organisms belong to the Cryptococcus spp., which was indeed by its shape on Sabouraud dextrose agar, Gram-stained smear suggestive C. neoformans, and confirmed on PCR. Our report is one of the worldwide rare reports linking cryptococcosis to cutaneous granuloma in equines and the first to provide a molecular confirmation of the cryptococcal involvement. The report highlights the importance of considering cryptococcosis in differential diagnosis of infectious cutaneous masses in equines.

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Titel: Pathological and molecular detection of a rare case of cutaneous cryptococcosis in a 9-year-old horse
verfasst von: Abdelmoneim Ali
Bakr Ahmed
Naif AlGabri
Mohamed Abdelmoneim
Mohamed Gomaa
Ahmed N. F. Neamat-Allah
Publikationsdatum: 14.04.2020
Verlag: Springer London
Erschienen in: Comparative Clinical Pathology / Ausgabe 4/2020
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-020-03105-z

Springer Medizin

Pathological and molecular detection of a rare case of cutaneous cryptococcosis in a 9-year-old horse

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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