Erschienen in:
01.02.2016 | Letter to the Editor
Chronic inflammation in offspring of patients with type 2 diabetes and albuminuria
verfasst von:
Angela De Matthaeis, Antonia Di Lorenzo, Alessia Gargano, Gianluigi Vendemiale, Simonetta Bacci, Salvatore De Cosmo
Erschienen in:
Acta Diabetologica
|
Ausgabe 1/2016
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Excerpt
Albuminuria, a key feature of diabetic nephropathy, is one of the strongest predictors of cardiovascular events in patients with type 2 diabetes (T2DM) [
1]. Moreover, it is well known the role for chronic inflammation (CI) as underlying pathogenic mechanism of atherosclerosis in non-diabetic and diabetic subjects. Recent evidences show that CI is also as a potential mediator between albuminuria and macrovascular disease [
2]. Fibrinogen and C-reactive protein (CRP), both markers of inflammatory response, are consistently associated with the future cardiovascular events also in apparently healthy individuals [
3]. …