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Acta Diabetologica

Acta Diabetologica OnlineFirst articles

18.11.2017 | Original Article Open Access

The potential role of the osteopontin–osteocalcin–osteoprotegerin triad in the pathogenesis of prediabetes in humans

Type 2 diabetes mellitus (T2DM) is a progressive disease, preceded by a preclinical phase of impaired glucose regulation, in the fasting state and/or in the postprandial state (IFG, impaired fasting glucose, and IGT, impaired glucose tolerance) [ 1 …]. A number of alterations involving different tissues have been found to contribute to the development and progression of hyperglycemia, and more relevantly, the progressive alterations of insulin, glucagon, and somatostatin production and secretion from the endocrine pancreas and insulin action in skeletal muscle, liver, and adipose tissue are the known hallmarks of prediabetes and T2DM [

18.11.2017 | Original Article

Association between different dietary polyphenol subclasses and the improvement in cardiometabolic risk factors: evidence from a randomized controlled clinical trial

In recent years, major advances have been made in the understanding of the effects of dietary polyphenol on several cardiometabolic risk factors, which may explain the beneficial association between a lower risk of chronic diseases and the intake …

17.11.2017 | Original Article

Substantial improvement in HbA1c following a treatment and teaching programme for people with type 2 diabetes on conventional insulin therapy in an in- and outpatient setting

National and international guidelines recommend that initiation of insulin therapy should include a structured diabetes treatment and teaching programme (DTTP) [ 1 , 2 ]. Nevertheless, a considerable number of these individuals have problems during …

14.11.2017 | Short Communication

Efficacy of self-monitoring blood glucose as a key component of a chronic care model versus usual care in type 2 diabetes patients treated with oral agents: results of a randomized trial

13.11.2017 | Short Communication

Impact of variations in duodenal glucose load on insulin clearance in health and type 2 diabetes

Up to 70% of secreted insulin is degraded or cleared prior to entering the systemic circulation, primarily in the liver which represents an important mechanism in the regulation of glucose homeostasis [ 1 ]. Insulin clearance is known to be reduced …

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Über diese Zeitschrift

Acta Diabetologica is a journal that publishes reports of experimental and clinical research on diabetes mellitus and related metabolic diseases. Original contributions on biochemical, physiological, pathophysiological and clinical aspects of research on diabetes and metabolic diseases are welcome. Reports are published in the form of original articles, short communications and letters to the editor. Invited reviews and editorials are also published. A Methodology forum, which publishes contributions on methodological aspects of diabetes in vivo and in vitro, is also available. The Editor-in-chief will be pleased to consider articles describing new techniques (e.g., new transplantation methods, metabolic models), of innovative importance in the field of diabetes/metabolism. Finally, workshop reports are also welcome in Acta Diabetologica.

The journal is also open for publication of supplements and for publishing abstracts of scientific meetings. Condition can be obtained from the Editor-in Chief or the publisher.

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