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30.07.2016 | Original Article

Correlation of cognitive and masticatory function in Alzheimer’s disease

verfasst von: Camila Heitor Campos, Giselle Rodrigues Ribeiro, José Luiz Riani Costa, Renata Cunha Matheus Rodrigues Garcia

Erschienen in: Clinical Oral Investigations | Ausgabe 2/2017

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Abstract

Objectives

This study investigated chewing function in elderly individuals with Alzheimer’s disease (AD) and correlated chewing function with cognitive status.

Materials and methods

Sixteen elderly individuals with mild AD (mean age 76.7 ± 6.3 years; 8 men, 8 women) and 16 age and gender-matched healthy controls (mean age 75.23 ± 4.4 years; 8 men, 8 women) were included in this study. All volunteers wore removable prostheses: 11 were totally edentulous and five were partially edentulous in each group. Chewing function was evaluated via masticatory performance (MP) using Optocal chewable test material and a sieve fractionation method. Cognitive functioning was assessed by the Mini Mental State Exam (MMSE), administered by a trained examiner. Data were analyzed by non-paired t test and Pearson’s correlation with α = 0.05.

Results

Compared to controls, mild AD patients had decreased MP (P < 0.01) and MMSE (P = 0.01). MP showed a moderate negative correlation with MMSE (r = −0.69).

Conclusions

Mild AD was associated with impaired chewing function.

Clinical relevance

Knowledge that mild AD has an impact on chewing is important for dental professionals in decision-making related to prosthetics and general dental treatment.

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Titel: Correlation of cognitive and masticatory function in Alzheimer’s disease
verfasst von: Camila Heitor Campos
Giselle Rodrigues Ribeiro
José Luiz Riani Costa
Renata Cunha Matheus Rodrigues Garcia
Publikationsdatum: 30.07.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 2/2017
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-016-1923-z

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Correlation of cognitive and masticatory function in Alzheimer’s disease