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Clinical Rheumatology

Erschienen in:

01.11.2015 | Review Article

Enthesitis-related arthritis

verfasst von: Amita Aggarwal, Durga Prasanna Misra

Erschienen in: Clinical Rheumatology | Ausgabe 11/2015

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Abstract

Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of childhood. Currently, it is characterized by seven categories. The enthesitis-related arthritis (ERA) category usually affects boys older than 6 years and presents with lower limb asymmetrical arthritis associated with enthesitis. Later, these children can develop inflammatory lumbosacral pain (IBP). These children are at risk of developing acute anterior uveitis. A recently devised disease activity index, Juvenile Spondyloarthropathy Disease Activity Index (JSpADA), has been validated in retrospective cohorts. The corner stone of treatment is NSAIDs, local corticosteroid injections, and exercise. Methotrexate and sulfasalazine can be used for peripheral arthritis while anti-tumor necrosis factor (TNF) agents are sometimes used to treat refractory enthesitis and sacroiliitis. Almost two third of patients with ERA have persistent disease and often have impairments in their quality of life. The presence of hip or ankle arthritis and a family history of spondyloarthropathy or polyarticular joint involvement at onset are associated with poorer prognosis.

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Titel: Enthesitis-related arthritis
verfasst von: Amita Aggarwal
Durga Prasanna Misra
Publikationsdatum: 01.11.2015
Verlag: Springer London
Erschienen in: Clinical Rheumatology / Ausgabe 11/2015
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-015-3029-4

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