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Erschienen in: Techniques in Coloproctology 2/2013

01.04.2013 | Practice Parameters

The treatment of squamous anal carcinoma: guidelines of the Italian society of colo-rectal surgery

verfasst von: I. Giani, M. Mistrangelo, C. Fucini

Erschienen in: Techniques in Coloproctology | Ausgabe 2/2013

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Abstract

The Italian society of colo-rectal surgery (SICCR) is dedicated to improving the study, prevention and management of the diseases of the colon, rectum and anus. One of the aims of the society is to establish guidelines to the treatment of these diseases. These guidelines are based on the international literature and on the best available evidence. Clinical practice guidelines are one of the most important instruments to provide therapeutic decision-making support, based on the best scientific evidence available at the time. Guidelines are advisory and not prescriptive, susceptible to continual variations secondary to innovations and new scientific evidence. These guidelines are a guide for all colo-rectal surgeons and physicians who approach anal cancer.
Literatur
1.
Zurück zum Zitat Cook DJ, Guyatt GH, Laupacis A, Sackett DL (1992) Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 102:S305–S311 Cook DJ, Guyatt GH, Laupacis A, Sackett DL (1992) Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 102:S305–S311
2.
3.
Zurück zum Zitat Klas J, Rothenberger D, Wong WD, Madoff R (1999) Malignant tumors of the anal canal. The spectrum of disease, treatment and outcome. Cancer 85:1686–1693PubMedCrossRef Klas J, Rothenberger D, Wong WD, Madoff R (1999) Malignant tumors of the anal canal. The spectrum of disease, treatment and outcome. Cancer 85:1686–1693PubMedCrossRef
4.
Zurück zum Zitat Minsky BD, Hoffman JP, Kelsen DP (2001) Cancer of the anal region. In: DeVita VT Jr, Hellman S, Rosenberg SA (eds) Cancer: principles & practice of oncology, 6th edn. Lippincott-Williams & Wilkins, Philadelphia, pp 1319–1342 Minsky BD, Hoffman JP, Kelsen DP (2001) Cancer of the anal region. In: DeVita VT Jr, Hellman S, Rosenberg SA (eds) Cancer: principles & practice of oncology, 6th edn. Lippincott-Williams & Wilkins, Philadelphia, pp 1319–1342
5.
Zurück zum Zitat Tanum G (1991) Diagnosis of anal carcinoma-doctor’s finger still the best? Oncology 48:383–386PubMedCrossRef Tanum G (1991) Diagnosis of anal carcinoma-doctor’s finger still the best? Oncology 48:383–386PubMedCrossRef
6.
7.
8.
Zurück zum Zitat Frisch M, Fenger C, van den Brule AJ et al (1999) Variants of squamous cell carcinoma of the anal canal and perianal skin and their relation to human papilloma viruses. Cancer Res 59:753–757PubMed Frisch M, Fenger C, van den Brule AJ et al (1999) Variants of squamous cell carcinoma of the anal canal and perianal skin and their relation to human papilloma viruses. Cancer Res 59:753–757PubMed
9.
Zurück zum Zitat Holmes F, Borek D, Owen-Kummer M et al (1988) Anal cancer in women. Gastroenterology 95:107–111PubMed Holmes F, Borek D, Owen-Kummer M et al (1988) Anal cancer in women. Gastroenterology 95:107–111PubMed
10.
Zurück zum Zitat Ryan DP, Mayer RJ (2000) Anal carcinoma: histology, staging, epidemiology, treatment. Curr Opin Oncol 12:345–352PubMedCrossRef Ryan DP, Mayer RJ (2000) Anal carcinoma: histology, staging, epidemiology, treatment. Curr Opin Oncol 12:345–352PubMedCrossRef
11.
Zurück zum Zitat Beckmann AM, Daling JR, Sherman KJ et al (1989) Human papillomavirus infection and anal cancer. Int J Cancer 43:1042–1049PubMedCrossRef Beckmann AM, Daling JR, Sherman KJ et al (1989) Human papillomavirus infection and anal cancer. Int J Cancer 43:1042–1049PubMedCrossRef
12.
Zurück zum Zitat Williams GR, Talbot IC (1994) Anal carcinoma: a histological review. Histopathology 25:507–516PubMedCrossRef Williams GR, Talbot IC (1994) Anal carcinoma: a histological review. Histopathology 25:507–516PubMedCrossRef
13.
Zurück zum Zitat Palmer JG, Scholefield JH, Coates PJ et al (1989) Anal cancer and human papillomaviruses. Dis Colon Rectum 32:1016–1022PubMedCrossRef Palmer JG, Scholefield JH, Coates PJ et al (1989) Anal cancer and human papillomaviruses. Dis Colon Rectum 32:1016–1022PubMedCrossRef
14.
Zurück zum Zitat Morson BC, Sobin LH (1976) Histological typing of intestinal tumours. In International histological classification of tumors, no 15. World Health Organization, Geneva Morson BC, Sobin LH (1976) Histological typing of intestinal tumours. In International histological classification of tumors, no 15. World Health Organization, Geneva
15.
Zurück zum Zitat Cummings BJ, Keane TJ, OSullivan B, Wong CS, Catton CN (1991) Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. Int J Rad Oncol Biol Phys 21:1115–1125CrossRef Cummings BJ, Keane TJ, OSullivan B, Wong CS, Catton CN (1991) Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. Int J Rad Oncol Biol Phys 21:1115–1125CrossRef
16.
Zurück zum Zitat Greene FL, Page DL, Fleming ID et al (2002) American joint committee on cancer: AJCC cancer staging manual, 6th edn. Springer, New York, pp 157–164 Greene FL, Page DL, Fleming ID et al (2002) American joint committee on cancer: AJCC cancer staging manual, 6th edn. Springer, New York, pp 157–164
17.
Zurück zum Zitat Friedlander MA, Stier E, Lin O (2004) Anorectal cytology as a screening tool for anal squamous lesions. Cancer 102:19–26PubMedCrossRef Friedlander MA, Stier E, Lin O (2004) Anorectal cytology as a screening tool for anal squamous lesions. Cancer 102:19–26PubMedCrossRef
18.
Zurück zum Zitat Gerard JP, Chapet O, Samiei F et al (2001) Management of inguinal lymph node metastases in patients with carcinoma of the anal canal: experience in a series of 270 patients treated in Lyon and review of the literature. Cancer 92:77–84PubMedCrossRef Gerard JP, Chapet O, Samiei F et al (2001) Management of inguinal lymph node metastases in patients with carcinoma of the anal canal: experience in a series of 270 patients treated in Lyon and review of the literature. Cancer 92:77–84PubMedCrossRef
19.
Zurück zum Zitat Arnott SJ, Cunningham D, Gallagher J et al (1996) Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. Lancet 348:1049–1054CrossRef Arnott SJ, Cunningham D, Gallagher J et al (1996) Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. Lancet 348:1049–1054CrossRef
20.
Zurück zum Zitat Bartelink H, Roelofsen F, Eschwege F et al (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European organization for research and treatment of cancer radiotherapy and gastrointestinal cooperative groups. J Clin Oncol 15:2040–2049PubMed Bartelink H, Roelofsen F, Eschwege F et al (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European organization for research and treatment of cancer radiotherapy and gastrointestinal cooperative groups. J Clin Oncol 15:2040–2049PubMed
21.
Zurück zum Zitat American Joint Committee on Cancer (1997) AJCC cancer staging manual, 5th edn. Lippincott-Raven Publishers, Philadelphia American Joint Committee on Cancer (1997) AJCC cancer staging manual, 5th edn. Lippincott-Raven Publishers, Philadelphia
22.
Zurück zum Zitat Mistrangelo M, Morino M (2009) Sentinel lymph node biopsy in anal cancer: a review. Gastroenterol Clin Biol 33:446–450PubMedCrossRef Mistrangelo M, Morino M (2009) Sentinel lymph node biopsy in anal cancer: a review. Gastroenterol Clin Biol 33:446–450PubMedCrossRef
23.
Zurück zum Zitat Tarantino D, Bernstein MA (2002) Endoanal ultrasound in the staging and management of squamous-cell carcinoma of the anal canal: potential implications of a new ultrasound staging system. Dis Colon Rectum 45:16–22PubMedCrossRef Tarantino D, Bernstein MA (2002) Endoanal ultrasound in the staging and management of squamous-cell carcinoma of the anal canal: potential implications of a new ultrasound staging system. Dis Colon Rectum 45:16–22PubMedCrossRef
24.
Zurück zum Zitat Martellucci J, Naldini G, Colosimo C, Cionini L, Rossi M (2009) Accuracy of endoanal ultrasound in the follow-up assessment for squamous cell carcinoma of the anal canal treated with radiochemotherapy. Surg Endosc 23:1054–1057PubMedCrossRef Martellucci J, Naldini G, Colosimo C, Cionini L, Rossi M (2009) Accuracy of endoanal ultrasound in the follow-up assessment for squamous cell carcinoma of the anal canal treated with radiochemotherapy. Surg Endosc 23:1054–1057PubMedCrossRef
25.
Zurück zum Zitat Cotter SE, Grigsby PW, Siegel BA et al (2006) FDG-PET/CT in the evaluation of anal carcinoma. Int J Radiat Oncol Biol Phys 65:720–725PubMedCrossRef Cotter SE, Grigsby PW, Siegel BA et al (2006) FDG-PET/CT in the evaluation of anal carcinoma. Int J Radiat Oncol Biol Phys 65:720–725PubMedCrossRef
26.
Zurück zum Zitat Anderson C, Koshy M, Staley C et al (2007) PET-CT fusion in radiation management of patients with anorectal tumors. Int J Radiat Oncology Biol Phys 69:155–162CrossRef Anderson C, Koshy M, Staley C et al (2007) PET-CT fusion in radiation management of patients with anorectal tumors. Int J Radiat Oncology Biol Phys 69:155–162CrossRef
27.
Zurück zum Zitat Nguyen BT, Joon DL, Khoo V et al (2008) Assessing the impact of FDG-PET in the management of anal cancer. Radiother Oncol 87:376–382PubMedCrossRef Nguyen BT, Joon DL, Khoo V et al (2008) Assessing the impact of FDG-PET in the management of anal cancer. Radiother Oncol 87:376–382PubMedCrossRef
28.
Zurück zum Zitat de Winton E, Heriot AG, Ng M et al (2009) The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer. Br J Cancer 100:693–700PubMedCrossRef de Winton E, Heriot AG, Ng M et al (2009) The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer. Br J Cancer 100:693–700PubMedCrossRef
29.
Zurück zum Zitat Renaud S, Guillermand S, Eberlé-Pouzeratte MC et al (2009) Apport de la tomographie par émission de positrons au 18F-fluorodéoxyglucose (TEP-FDG) dans la prise en charge du cancer du canal anal. Med Nucl 33:415–424 Renaud S, Guillermand S, Eberlé-Pouzeratte MC et al (2009) Apport de la tomographie par émission de positrons au 18F-fluorodéoxyglucose (TEP-FDG) dans la prise en charge du cancer du canal anal. Med Nucl 33:415–424
30.
Zurück zum Zitat Mistrangelo M, Pelosi E, Bellò M et al (2010) Comparison of positron emission tomography scanning and sentinel node biopsy in the detection of inguinal node metastases in patients with anal cancer. Int J Radiation Oncol Biol Phys 77:73–78CrossRef Mistrangelo M, Pelosi E, Bellò M et al (2010) Comparison of positron emission tomography scanning and sentinel node biopsy in the detection of inguinal node metastases in patients with anal cancer. Int J Radiation Oncol Biol Phys 77:73–78CrossRef
31.
Zurück zum Zitat Franceschi S, De Vuyst H (2009) Human papillomavirus vaccines and anal carcinoma. Curr Opin HIV AIDS 4:57–63PubMedCrossRef Franceschi S, De Vuyst H (2009) Human papillomavirus vaccines and anal carcinoma. Curr Opin HIV AIDS 4:57–63PubMedCrossRef
32.
Zurück zum Zitat Monsonego J (2010) Anal cancer and human papillomaviruses: a perspective based on the cervical cancer model. Gynecol Obstet Fertil 38:250–254PubMedCrossRef Monsonego J (2010) Anal cancer and human papillomaviruses: a perspective based on the cervical cancer model. Gynecol Obstet Fertil 38:250–254PubMedCrossRef
33.
Zurück zum Zitat Edge SE, Byrd DR, Compton CC et al (2009) AJCC cancer staging manual, 7th edn. Springer, New York Edge SE, Byrd DR, Compton CC et al (2009) AJCC cancer staging manual, 7th edn. Springer, New York
34.
Zurück zum Zitat Martenson JA, Gunderson LL (1993) External radiation therapy without chemotherapy in the management of anal cancer. Cancer 71:1736–1740PubMedCrossRef Martenson JA, Gunderson LL (1993) External radiation therapy without chemotherapy in the management of anal cancer. Cancer 71:1736–1740PubMedCrossRef
35.
Zurück zum Zitat Ajani JA, Winter KA, Gunderson LL et al (2006) Intergroup RTOG 98-11: a phase III randomized study of 5-fluorouracil (5-FU), mitomycin, and radiotherapy versus 5-fluorouracil, cisplatin and radiotherapy in carcinoma of the anal canal. J Clin Oncol 24:4009 Ajani JA, Winter KA, Gunderson LL et al (2006) Intergroup RTOG 98-11: a phase III randomized study of 5-fluorouracil (5-FU), mitomycin, and radiotherapy versus 5-fluorouracil, cisplatin and radiotherapy in carcinoma of the anal canal. J Clin Oncol 24:4009
36.
Zurück zum Zitat Faynsod M, Vargas H, Tolmos J et al (2000) Patterns of recurrence in anal canal carcinoma. Arch Surg 135:1090–1095PubMedCrossRef Faynsod M, Vargas H, Tolmos J et al (2000) Patterns of recurrence in anal canal carcinoma. Arch Surg 135:1090–1095PubMedCrossRef
37.
Zurück zum Zitat International Union Against Cancer (1987) TNM classification of malignant tumors, 4th edn. In: Hermanek P, Sobin LH (eds) Springer, New York International Union Against Cancer (1987) TNM classification of malignant tumors, 4th edn. In: Hermanek P, Sobin LH (eds) Springer, New York
38.
Zurück zum Zitat American Joint Committee on Cancer (1987) Manual for staging of cancer, 3rd edn. J B Lippincott, Philadelphia American Joint Committee on Cancer (1987) Manual for staging of cancer, 3rd edn. J B Lippincott, Philadelphia
39.
Zurück zum Zitat Nigro ND (1987) Multidisciplinary management of carcinoma of the anus. World J Surg 11:446–451PubMedCrossRef Nigro ND (1987) Multidisciplinary management of carcinoma of the anus. World J Surg 11:446–451PubMedCrossRef
40.
Zurück zum Zitat Nigro ND, Vaitkevicius VK, Considine B (1974) Combined therapy for cancer of the anal canal. A preliminary report. Dis Colon Rectum 17:354–356PubMedCrossRef Nigro ND, Vaitkevicius VK, Considine B (1974) Combined therapy for cancer of the anal canal. A preliminary report. Dis Colon Rectum 17:354–356PubMedCrossRef
41.
Zurück zum Zitat Fuchshuber PR, Rodriguez-Bigas M, Weber T, Petrelli NJ (1997) Anal canal and perianal epidermoid cancers. J Am Coll Surg 185:494–505PubMed Fuchshuber PR, Rodriguez-Bigas M, Weber T, Petrelli NJ (1997) Anal canal and perianal epidermoid cancers. J Am Coll Surg 185:494–505PubMed
42.
Zurück zum Zitat Constantinou EC, Daly W, Fung CY et al (1997) Time-dose considerations in the treatment of anal cancer. Int J Radiat Oncol Biol Phys 39:651–657PubMedCrossRef Constantinou EC, Daly W, Fung CY et al (1997) Time-dose considerations in the treatment of anal cancer. Int J Radiat Oncol Biol Phys 39:651–657PubMedCrossRef
43.
Zurück zum Zitat Touboul E, Schlienger M, Buffat L et al (1994) Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients. Cancer 73:1569–1579PubMedCrossRef Touboul E, Schlienger M, Buffat L et al (1994) Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients. Cancer 73:1569–1579PubMedCrossRef
44.
Zurück zum Zitat Graf R, Wust P, Hildebrandt B et al (2003) Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy. Oncology 65:14–22PubMedCrossRef Graf R, Wust P, Hildebrandt B et al (2003) Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy. Oncology 65:14–22PubMedCrossRef
45.
Zurück zum Zitat Deniaud-Alexandre E, Touboul E, Tiret E et al (2003) Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients. Cancer Radiotherapie 7:237–253PubMedCrossRef Deniaud-Alexandre E, Touboul E, Tiret E et al (2003) Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients. Cancer Radiotherapie 7:237–253PubMedCrossRef
46.
Zurück zum Zitat Berry JM, Palefsky JM, Welton ML (2004) Anal cancer and its precursors in HIV-positive patients: perspectives and management. Surg Oncol Clin N Am 13:355–373PubMedCrossRef Berry JM, Palefsky JM, Welton ML (2004) Anal cancer and its precursors in HIV-positive patients: perspectives and management. Surg Oncol Clin N Am 13:355–373PubMedCrossRef
47.
Zurück zum Zitat Papaconstantinou HT, Bullard KM, Rothenberger DA, Madoff RD (2006) Salvage abdominoperineal resection after failed Nigro protocol: modest success, major morbidity. Colorectal Dis 8:124–129PubMedCrossRef Papaconstantinou HT, Bullard KM, Rothenberger DA, Madoff RD (2006) Salvage abdominoperineal resection after failed Nigro protocol: modest success, major morbidity. Colorectal Dis 8:124–129PubMedCrossRef
48.
Zurück zum Zitat Renehan AG, Saunders MP, Schofield PF, ODwyer ST (2005) Patterns of local disease failure and outcome after salvage surgery in patients with anal cancer. Br J Surg 92:605–614PubMedCrossRef Renehan AG, Saunders MP, Schofield PF, ODwyer ST (2005) Patterns of local disease failure and outcome after salvage surgery in patients with anal cancer. Br J Surg 92:605–614PubMedCrossRef
49.
Zurück zum Zitat Das P, Bhatia S, Eng C et al (2007) Predictors and patterns of recurrence after definitive chemoradiation for anal cancer. Int J Rad Oncol Biol Phys 68:794–800CrossRef Das P, Bhatia S, Eng C et al (2007) Predictors and patterns of recurrence after definitive chemoradiation for anal cancer. Int J Rad Oncol Biol Phys 68:794–800CrossRef
50.
Zurück zum Zitat Nilsson PJ, Svensson C, Goldman S, Glimelius B (2002) Salvage abdominoperineal resection in anal epidermoid cancer. Br J Surg 89:1425–1429PubMedCrossRef Nilsson PJ, Svensson C, Goldman S, Glimelius B (2002) Salvage abdominoperineal resection in anal epidermoid cancer. Br J Surg 89:1425–1429PubMedCrossRef
51.
Zurück zum Zitat Akbari RP, Paty PB, Guillem JG et al (2004) Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy. Dis Colon Rectum 47:1136–1144PubMedCrossRef Akbari RP, Paty PB, Guillem JG et al (2004) Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy. Dis Colon Rectum 47:1136–1144PubMedCrossRef
52.
Zurück zum Zitat Carey RW (1984) Regression of pulmonary metastases from cloacogenic carcinoma after cis-platinum/5-fluorouracil treatment. J Clin Gastroenterol 6:257–259PubMed Carey RW (1984) Regression of pulmonary metastases from cloacogenic carcinoma after cis-platinum/5-fluorouracil treatment. J Clin Gastroenterol 6:257–259PubMed
53.
Zurück zum Zitat Ajani JA, Carrasco CH, Jackson DE, Wallace S (1989) Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal. Am J Med 87:221–224PubMedCrossRef Ajani JA, Carrasco CH, Jackson DE, Wallace S (1989) Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal. Am J Med 87:221–224PubMedCrossRef
54.
Zurück zum Zitat Longo WE, Vernava AM, Wade TP et al (1994) Recurrent squamous cell carcinoma of the anal canal. Predictors of initial treatment failure and results of salvage therapy. Ann Surg 220:40–49PubMedCrossRef Longo WE, Vernava AM, Wade TP et al (1994) Recurrent squamous cell carcinoma of the anal canal. Predictors of initial treatment failure and results of salvage therapy. Ann Surg 220:40–49PubMedCrossRef
55.
Zurück zum Zitat Herzog U, Boss M, Spichtin H (1998) Endoanal ultrasonography in the follow-up of anal carcinoma. Surg Endosc 8:1186–1189CrossRef Herzog U, Boss M, Spichtin H (1998) Endoanal ultrasonography in the follow-up of anal carcinoma. Surg Endosc 8:1186–1189CrossRef
56.
Zurück zum Zitat Christensen AF, Nielsen MB, Svendsen LB, Engelholm SA (2006) Three-dimensional anal endosonography may improve detection of recurrent anal cancer. Dis Colon Rectum 49:1527–1532PubMedCrossRef Christensen AF, Nielsen MB, Svendsen LB, Engelholm SA (2006) Three-dimensional anal endosonography may improve detection of recurrent anal cancer. Dis Colon Rectum 49:1527–1532PubMedCrossRef
57.
Zurück zum Zitat Palefsky J, Holly EA, Hogeboom CJ et al (1998) Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr Hum Retrovirol 17:314–319PubMedCrossRef Palefsky J, Holly EA, Hogeboom CJ et al (1998) Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr Hum Retrovirol 17:314–319PubMedCrossRef
58.
Zurück zum Zitat Ogunbiyi OA, Scholefield JH, Raftery AT et al (1994) Prevalence of anal human papillomavirus infection and intraepithelial neoplasia in renal allograft recipients. Br J Surg 81:365–367PubMedCrossRef Ogunbiyi OA, Scholefield JH, Raftery AT et al (1994) Prevalence of anal human papillomavirus infection and intraepithelial neoplasia in renal allograft recipients. Br J Surg 81:365–367PubMedCrossRef
59.
Zurück zum Zitat Holly EA, Ralston ML, Darragh TM, Greenblatt RM, Jay N, Palefsky JM (2001) Prevalence and risk factors for anal squamous intraepithelial lesions in women. J Natl Cancer Inst 93:843–849PubMedCrossRef Holly EA, Ralston ML, Darragh TM, Greenblatt RM, Jay N, Palefsky JM (2001) Prevalence and risk factors for anal squamous intraepithelial lesions in women. J Natl Cancer Inst 93:843–849PubMedCrossRef
60.
Zurück zum Zitat Chin-Hong PV, Vittinghoff E, Cranston RD et al (2005) Age related prevalence of anal cancer precursors in homosexual men: the EXPLORE study. J Natl Cancer Inst 97:896–905PubMedCrossRef Chin-Hong PV, Vittinghoff E, Cranston RD et al (2005) Age related prevalence of anal cancer precursors in homosexual men: the EXPLORE study. J Natl Cancer Inst 97:896–905PubMedCrossRef
61.
Zurück zum Zitat Frisch M, Glimelius B, van den Brule AJ et al (1997) Sexually transmitted infection as a cause of anal cancer. N Engl J Med 337:1350–1358PubMedCrossRef Frisch M, Glimelius B, van den Brule AJ et al (1997) Sexually transmitted infection as a cause of anal cancer. N Engl J Med 337:1350–1358PubMedCrossRef
62.
Zurück zum Zitat Chang GJ, Welton ML (2003) Anal neoplasia. Sem Colon Rectal Surg 14:111–118CrossRef Chang GJ, Welton ML (2003) Anal neoplasia. Sem Colon Rectal Surg 14:111–118CrossRef
63.
Zurück zum Zitat Arbesman H, Ransohoff DF (1987) Is Bowens disease a predictor for the development of internal malignancy? A methodological critique of the literature. JAMA 257:516–518PubMedCrossRef Arbesman H, Ransohoff DF (1987) Is Bowens disease a predictor for the development of internal malignancy? A methodological critique of the literature. JAMA 257:516–518PubMedCrossRef
64.
Zurück zum Zitat Wieland U, Brockmeyer NH, Weissenborn SJ et al (2006) Imiquimod treatment of anal intraepithelial neoplasia in HIV-positive men. Arch Dermatol 142:1438–1444PubMedCrossRef Wieland U, Brockmeyer NH, Weissenborn SJ et al (2006) Imiquimod treatment of anal intraepithelial neoplasia in HIV-positive men. Arch Dermatol 142:1438–1444PubMedCrossRef
65.
Zurück zum Zitat Bargman H, Hochman J (2003) Topical treatment of Bowen’s disease with 5-fluorouracil. J Cutan Med Surg 7:101–105PubMedCrossRef Bargman H, Hochman J (2003) Topical treatment of Bowen’s disease with 5-fluorouracil. J Cutan Med Surg 7:101–105PubMedCrossRef
66.
Zurück zum Zitat Webber J, Fromm D (2004) Photodynamic therapy for carcinoma in situ of the anus. Arch Surg 139:259–261PubMedCrossRef Webber J, Fromm D (2004) Photodynamic therapy for carcinoma in situ of the anus. Arch Surg 139:259–261PubMedCrossRef
67.
Zurück zum Zitat Pineda CE, Berry JM, Welton ML (2006) High-resolution anoscopy and targeted treatment of high-grade squamous intraepithelial lesions. Dis Colon Rectum 49:126PubMedCrossRef Pineda CE, Berry JM, Welton ML (2006) High-resolution anoscopy and targeted treatment of high-grade squamous intraepithelial lesions. Dis Colon Rectum 49:126PubMedCrossRef
68.
Zurück zum Zitat Chang GJ, Berry JM, Jay N, Palefsky JM, Welton ML (2002) Surgical treatment of high-grade anal squamous intraepithelial lesions: a prospective study. Dis Colon Rectum 45:453–458PubMedCrossRef Chang GJ, Berry JM, Jay N, Palefsky JM, Welton ML (2002) Surgical treatment of high-grade anal squamous intraepithelial lesions: a prospective study. Dis Colon Rectum 45:453–458PubMedCrossRef
69.
Zurück zum Zitat Goldstone SE, Kawalek AZ, Huyett JW (2005) Infrared coagulator: a useful tool for treating anal squamous intraepithelial lesions. Dis Colon Rectum 48:1042–1054PubMedCrossRef Goldstone SE, Kawalek AZ, Huyett JW (2005) Infrared coagulator: a useful tool for treating anal squamous intraepithelial lesions. Dis Colon Rectum 48:1042–1054PubMedCrossRef
70.
Zurück zum Zitat Jay N, Berry JM, Hogeboom CJ, Holly EA, Darragh TM, Palefsky JM (1997) Colposcopic appearance of anal squamous intraepithelial lesions: relationship to histopathology. Dis Colon Rectum 40:919–928PubMedCrossRef Jay N, Berry JM, Hogeboom CJ, Holly EA, Darragh TM, Palefsky JM (1997) Colposcopic appearance of anal squamous intraepithelial lesions: relationship to histopathology. Dis Colon Rectum 40:919–928PubMedCrossRef
71.
Zurück zum Zitat Bertram P, Treutner KH, Rubben A, Hauptmann S, Schumpelick V (1995) Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Lowenstein tumor). Langenbecks Arch Chir 380:115–118PubMedCrossRef Bertram P, Treutner KH, Rubben A, Hauptmann S, Schumpelick V (1995) Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Lowenstein tumor). Langenbecks Arch Chir 380:115–118PubMedCrossRef
Metadaten
Titel
The treatment of squamous anal carcinoma: guidelines of the Italian society of colo-rectal surgery
verfasst von
I. Giani
M. Mistrangelo
C. Fucini
Publikationsdatum
01.04.2013
Verlag
Springer Milan
Erschienen in
Techniques in Coloproctology / Ausgabe 2/2013
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-012-0912-8

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Nur selten Nachblutungen nach Abszesstonsillektomie

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In einer Metaanalyse von 18 Studien war die Rate von Nachblutungen nach einer Abszesstonsillektomie mit weniger als 7% recht niedrig. Nur rund 2% der Behandelten mussten nachoperiert werden. Die Therapie scheint damit recht sicher zu sein.

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S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.