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01.02.2011 | Case Report

Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age

verfasst von: Naoyuki Miyashita, Takaya Maruyama, Tetsu Kobayashi, Hiroyasu Kobayashi, Osamu Taguchi, Yasuhiro Kawai, Tetsuya Yamaguchi, Kazunobu Ouchi, Mikio Oka

Erschienen in: Journal of Infection and Chemotherapy | Ausgabe 1/2011

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Abstract

A macrolide-resistant Mycoplasma pneumoniae strain was isolated from two patients with community-acquired pneumonia. The pneumonia severity score of both patients was mild, and rapid clinical improvement was seen after administration of fluoroquinolone. Clinical features of macrolide-resistant M. pneumoniae pneumonia were identical to those of macrolide-sensitive M. pneumoniae pneumonia. An A-to-G transition at position 2063 and 2064, respectively, in domain V of the 23S rRNA gene was identified. The minimum inhibitory concentration of erythromycin of these isolates was greatly elevated. In Japan, macrolide-resistant M. pneumoniae infections are common in pediatric patients but not in adults. However, physicians should pay attention to macrolide-resistant M. pneumoniae not only in children but also in adults.

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Titel: Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age
verfasst von: Naoyuki Miyashita
Takaya Maruyama
Tetsu Kobayashi
Hiroyasu Kobayashi
Osamu Taguchi
Yasuhiro Kawai
Tetsuya Yamaguchi
Kazunobu Ouchi
Mikio Oka
Publikationsdatum: 01.02.2011
Verlag: Springer Japan
Erschienen in: Journal of Infection and Chemotherapy / Ausgabe 1/2011
Print ISSN: 1341-321X
Elektronische ISSN: 1437-7780
DOI: https://doi.org/10.1007/s10156-010-0093-1

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