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Erschienen in: The International Journal of Cardiovascular Imaging 1/2016

01.01.2016 | Original Paper

Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis

verfasst von: Charis Costopoulos, Adam J. Brown, Zhongzhao Teng, Stephen P. Hoole, Nick E. J. West, Habib Samady, Martin R. Bennett

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 1/2016

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Abstract

Invasive imaging modalities, in particular intravascular ultrasound (IVUS) and optical coherence tomography (OCT), have become established tools for the in vivo study of coronary atherosclerosis. Their use in clinical studies has confirmed histopathological observations that certain important plaque features, such as thin fibrous caps and large lipid cores, are associated with plaque rupture, the precipitating event for the majority of myocardial infarctions. Serial imaging studies have also successfully been used for the evaluation of potential disease modifying pharmacological agents. Recent prospective IVUS studies have confirmed specific baseline imaging features associated with subsequent adverse clinical outcomes, although absolute event rates were too low for clinical utility. Development of hybrid IVUS–OCT imaging or integration of novel techniques, including near-infrared spectroscopy, plaque structural and endothelial shear stress, have great potential to improve our current ability to identify and stratify atheromatous plaques at risk of rupture.
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Metadaten
Titel
Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis
verfasst von
Charis Costopoulos
Adam J. Brown
Zhongzhao Teng
Stephen P. Hoole
Nick E. J. West
Habib Samady
Martin R. Bennett
Publikationsdatum
01.01.2016
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 1/2016
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-015-0701-3

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