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Journal of Assisted Reproduction and Genetics
Erschienen in: Journal of Assisted Reproduction and Genetics 7/2010

01.07.2010 | Assisted reproduction

Impact of short-term preconceptional exposure to particulate air pollution on treatment outcome in couples undergoing in vitro fertilization and embryo transfer (IVF/ET)

verfasst von: Paulo Marcelo Perin, Mariangela Maluf, Carlos Eduardo Czeresnia, Daniela Aparecida Nicolosi Foltran Januário, Paulo Hilário Nascimento Saldiva

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 7/2010

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Abstract

Purpose

To assess the potential effects of short-term exposure to particulate air pollution during follicular phase on clinical, laboratory, and pregnancy outcomes of women undergoing IVF/ET.

Methods

Retrospective cohort study of 400 first IVF/ET cycles of women exposed to ambient particulate matter during follicular phase. Particulate matter (PM) was categorized into quartiles (Q1: ≤30.48 µg/m3, Q2: 30.49–42.00 µg/m3, Q3: 42.01–56.72 µg/m3, and Q4: >56.72 µg/m3).

Results

Clinical, laboratory, or treatment variables were not affected by follicular phase PM exposure periods. Women exposed to Q4 period during the follicular phase of conception cycles had a higher risk of miscarriage (odds ratio, 5.05; 95% confidence interval: 1.04–25.51) when compared to women exposed to Q1–3 periods.

Conclusion

Our results show an association between brief exposure to high levels of ambient PM during the preconceptional period and early pregnancy loss, although no effect of this exposure on clinical, laboratory, and treatment outcomes was observed.
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Metadaten
Titel
Impact of short-term preconceptional exposure to particulate air pollution on treatment outcome in couples undergoing in vitro fertilization and embryo transfer (IVF/ET)
verfasst von
Paulo Marcelo Perin
Mariangela Maluf
Carlos Eduardo Czeresnia
Daniela Aparecida Nicolosi Foltran Januário
Paulo Hilário Nascimento Saldiva
Publikationsdatum
01.07.2010
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 7/2010
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-010-9419-2

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