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Erschienen in: Journal of Assisted Reproduction and Genetics 5/2011

01.05.2011 | Assisted Reproduction Technologies

The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

verfasst von: Laura Governini, Raoul Orvieto, Cristiana Guerranti, Laura Gambera, Vincenzo De Leo, Paola Piomboni

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 5/2011

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Abstract

In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R = 0.75; P < 0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p < 0.02) and number of embryos transferred (p < 0.02), compared to the PFC negative group.
Literatur
1.
Zurück zum Zitat Sharpe RM. Hormones and testis development and the possible adverse effect of environmental chemicals. Toxicol Lett. 2001;20:221–32.CrossRef Sharpe RM. Hormones and testis development and the possible adverse effect of environmental chemicals. Toxicol Lett. 2001;20:221–32.CrossRef
2.
Zurück zum Zitat Taskinen HK, Kyyronen P, Sallmen M, Virtanen SV, Liukkonen TA, Huida O, et al. Reduced fertility among female wood workers exposed to formaldehyde. Am J Ind Med. 1999;36:206–12.PubMedCrossRef Taskinen HK, Kyyronen P, Sallmen M, Virtanen SV, Liukkonen TA, Huida O, et al. Reduced fertility among female wood workers exposed to formaldehyde. Am J Ind Med. 1999;36:206–12.PubMedCrossRef
3.
Zurück zum Zitat Law DC, Klebanoff MA, Brock JW, Dunson DB, Longnecker MP. Maternal serum levels of polychlorinated biphenyls and 1, 1-dichloro-2, 2-bis (p-chlorophenyl)ethylene (DDE) and time to pregnancy. Am J Epidemiol. 2005;162:523–32.PubMedCrossRef Law DC, Klebanoff MA, Brock JW, Dunson DB, Longnecker MP. Maternal serum levels of polychlorinated biphenyls and 1, 1-dichloro-2, 2-bis (p-chlorophenyl)ethylene (DDE) and time to pregnancy. Am J Epidemiol. 2005;162:523–32.PubMedCrossRef
4.
Zurück zum Zitat Calafat AM, Wong LY, Kuklenyik Z, Reidy JA, Needham LL. Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and comparisons with NHANES 1999–2000. Environ Health Perspect. 2007;115:1596–602.PubMedCrossRef Calafat AM, Wong LY, Kuklenyik Z, Reidy JA, Needham LL. Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and comparisons with NHANES 1999–2000. Environ Health Perspect. 2007;115:1596–602.PubMedCrossRef
5.
Zurück zum Zitat Renner R. Growing concern over perfluorinated chemicals. Environ Sci Technol. 2001;39:A154–160.CrossRef Renner R. Growing concern over perfluorinated chemicals. Environ Sci Technol. 2001;39:A154–160.CrossRef
6.
Zurück zum Zitat Tittlemier S, Ryan JJ, Oostdam JV. Presence of anionic perfluorinated organic compounds in serum collected from Northern Canadian populations. Organohalogen Compound. 2004;66:4009–14. Tittlemier S, Ryan JJ, Oostdam JV. Presence of anionic perfluorinated organic compounds in serum collected from Northern Canadian populations. Organohalogen Compound. 2004;66:4009–14.
7.
Zurück zum Zitat Giesy JP, Kannan K. Global distribution of perfluorooctane sulfonate in wildlife. Environ Sci Technol. 2001;35:1339–42.PubMedCrossRef Giesy JP, Kannan K. Global distribution of perfluorooctane sulfonate in wildlife. Environ Sci Technol. 2001;35:1339–42.PubMedCrossRef
8.
Zurück zum Zitat Midasch O, Drexler H, Hart N, Beckmann MW, Angerer J. Transplacental exposure of neonates to perfluorooctane sulfonate and perfluorooctanoate: a pilot study. Int Arch Occup Environ Health. 2007;80:643–8.PubMedCrossRef Midasch O, Drexler H, Hart N, Beckmann MW, Angerer J. Transplacental exposure of neonates to perfluorooctane sulfonate and perfluorooctanoate: a pilot study. Int Arch Occup Environ Health. 2007;80:643–8.PubMedCrossRef
9.
Zurück zum Zitat Fei CY, McLaughlin JK, Tarone RE, Olsen J. Perfluorinated chemicals and fetal growth: a study within the Danish National Birth Cohort. Environ Health Perspect. 2007;115:1677–82.PubMedCrossRef Fei CY, McLaughlin JK, Tarone RE, Olsen J. Perfluorinated chemicals and fetal growth: a study within the Danish National Birth Cohort. Environ Health Perspect. 2007;115:1677–82.PubMedCrossRef
10.
Zurück zum Zitat Fei C, McLaughlin JK, Lipworth L, Olsen J. Maternal levels of perfluorinated chemicals and subfecundity. Hum Reprod. 2009;24:1200–5.PubMedCrossRef Fei C, McLaughlin JK, Lipworth L, Olsen J. Maternal levels of perfluorinated chemicals and subfecundity. Hum Reprod. 2009;24:1200–5.PubMedCrossRef
11.
Zurück zum Zitat Austin ME, Kasturi BS, Barber M, Kannan K, MohanKumar PS, MohanKumar SM. Neuroendocrine effects of perfluorooctane sulfonate in rats. Environ Health Perspect. 2003;111:1485–9.PubMedCrossRef Austin ME, Kasturi BS, Barber M, Kannan K, MohanKumar PS, MohanKumar SM. Neuroendocrine effects of perfluorooctane sulfonate in rats. Environ Health Perspect. 2003;111:1485–9.PubMedCrossRef
12.
Zurück zum Zitat Ebner T, Moser M, Sommergruber M, Tews G. Selection based on morphological assessment of oocytes and embryos at different stages of preimplantation development: a review. Hum Reprod Update. 2003;9:251–62.PubMedCrossRef Ebner T, Moser M, Sommergruber M, Tews G. Selection based on morphological assessment of oocytes and embryos at different stages of preimplantation development: a review. Hum Reprod Update. 2003;9:251–62.PubMedCrossRef
13.
Zurück zum Zitat Hansen KJ, Clemen LA, Ellefson ME, Johnson HO. Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices. Environ Sci Technol. 2001;35:766–70.PubMedCrossRef Hansen KJ, Clemen LA, Ellefson ME, Johnson HO. Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices. Environ Sci Technol. 2001;35:766–70.PubMedCrossRef
14.
Zurück zum Zitat Kannan K, Hansen SP, Franson CJ, Bowerman WW, Hansen KJ, Jones PD, et al. Perfluorooctane sulfonate in fish-eating water birds including Bald Eagles and Albatrosses. Environ Sci Technol. 2001;35:3065–70.PubMedCrossRef Kannan K, Hansen SP, Franson CJ, Bowerman WW, Hansen KJ, Jones PD, et al. Perfluorooctane sulfonate in fish-eating water birds including Bald Eagles and Albatrosses. Environ Sci Technol. 2001;35:3065–70.PubMedCrossRef
15.
Zurück zum Zitat Corsolini S, Guerranti C, Perra G, Focardi S. Polybrominated diphenyl ethers, perfluorinated compounds and chlorinated pesticides in Swordfish (Xiphias glaudius) from the Mediterranean Sea. Environ Sci Technol. 2008;42:4344–9.PubMedCrossRef Corsolini S, Guerranti C, Perra G, Focardi S. Polybrominated diphenyl ethers, perfluorinated compounds and chlorinated pesticides in Swordfish (Xiphias glaudius) from the Mediterranean Sea. Environ Sci Technol. 2008;42:4344–9.PubMedCrossRef
16.
Zurück zum Zitat Oliva A, Spira A, Multigner L. Contribution of environmental factors to the risk of male infertility. Hum Reprod. 2001;16:1768–76.PubMedCrossRef Oliva A, Spira A, Multigner L. Contribution of environmental factors to the risk of male infertility. Hum Reprod. 2001;16:1768–76.PubMedCrossRef
17.
Zurück zum Zitat Hauser R, Sokol R. Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult male. Fertil Steril. 2008;89:e59–65.PubMedCrossRef Hauser R, Sokol R. Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult male. Fertil Steril. 2008;89:e59–65.PubMedCrossRef
18.
Zurück zum Zitat Mendola P, Messer LC, Rappazzo K. Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult female. Fertil Steril. 2008;89:e81–94.PubMedCrossRef Mendola P, Messer LC, Rappazzo K. Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult female. Fertil Steril. 2008;89:e81–94.PubMedCrossRef
19.
Zurück zum Zitat Spanò M, Toft G, Hagmar L, Eleuteri P, Rescia M, Rignell-Hydbom A, et al. INUENDO. Exposure to PCB and p, p’-DDE in European and Inuit populations: impact on human sperm chromatin integrity. Hum Reprod. 2005;20:3488–99.PubMedCrossRef Spanò M, Toft G, Hagmar L, Eleuteri P, Rescia M, Rignell-Hydbom A, et al. INUENDO. Exposure to PCB and p, p’-DDE in European and Inuit populations: impact on human sperm chromatin integrity. Hum Reprod. 2005;20:3488–99.PubMedCrossRef
20.
Zurück zum Zitat Giwercman AH, Rignell-Hydbom A, Toft G, Rylander L, Hagmar L, Lindh C, et al. Reproductive hormone levels in men exposed to persistent organohalogen pollutants: a study of inuit and three European cohorts. Environ Health Perspect. 2006;114:1348–53.PubMedCrossRef Giwercman AH, Rignell-Hydbom A, Toft G, Rylander L, Hagmar L, Lindh C, et al. Reproductive hormone levels in men exposed to persistent organohalogen pollutants: a study of inuit and three European cohorts. Environ Health Perspect. 2006;114:1348–53.PubMedCrossRef
Metadaten
Titel
The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity
verfasst von
Laura Governini
Raoul Orvieto
Cristiana Guerranti
Laura Gambera
Vincenzo De Leo
Paola Piomboni
Publikationsdatum
01.05.2011
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 5/2011
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-011-9548-2

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