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Journal of Assisted Reproduction and Genetics
Erschienen in: Journal of Assisted Reproduction and Genetics 9/2016

07.06.2016 | Review

Recent advances in preimplantation genetic diagnosis and screening

verfasst von: Lina Lu, Bo Lv, Kevin Huang, Zhigang Xue, Xianmin Zhu, Guoping Fan

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 9/2016

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Abstract

Preimplantation genetic diagnosis/screening (PGD/PGS) aims to help couples lower the risks of transmitting genetic defects to their offspring, implantation failure, and/or miscarriage during in vitro fertilization (IVF) cycles. However, it is still being debated with regard to the practicality and diagnostic accuracy of PGD/PGS due to the concern of invasive biopsy and the potential mosaicism of embryos. Recently, several non-invasive and high-throughput assays have been developed to help overcome the challenges encountered in the conventional invasive biopsy and low-throughput analysis in PGD/PGS. In this mini-review, we will summarize the recent progresses of these new methods for PGD/PGS and discuss their potential applications in IVF clinics.
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Metadaten
Titel
Recent advances in preimplantation genetic diagnosis and screening
verfasst von
Lina Lu
Bo Lv
Kevin Huang
Zhigang Xue
Xianmin Zhu
Guoping Fan
Publikationsdatum
07.06.2016
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 9/2016
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-016-0750-0

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