Skip to main content
Erschienen in: Journal of Interventional Cardiac Electrophysiology 2/2009

01.03.2009 | CASE REPORT

Electrophysiologic and histopathologic findings of the ablation sites for ventricular fibrillation in a patient with ischemic cardiomyopathy

verfasst von: Akihiko Nogami, Shoichi Kubota, Masamitsu Adachi, Osamu Igawa

Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 2/2009

Einloggen, um Zugang zu erhalten

Abstract

We examined autopsy specimens from a patient with ischemic cardiomyopathy who underwent radiofrequency catheter ablation of ventricular fibrillation. There was site specific arrhythmogenesis of the trigger ventricular premature contractions (VPCs) and Purkinje potentials were recorded before the onset of the QRS. In postmortem examination, fibromuscular bands connecting the posterior papillary muscle and ventricular septum were recognized at the successful ablation sites of the trigger VPCs and the microscopic examinations revealed Purkinje cells in the center of that fibromuscular band.
Literatur
1.
Zurück zum Zitat Bänsch, D., Oyang, F., Antz, M., Arentz, T., Weber, R., Val-Mejias, J. E., et al. (2003). Successful catheter ablation of electrical storm after myocardial infarction. Circulation, 108, 3011–3016.PubMedCrossRef Bänsch, D., Oyang, F., Antz, M., Arentz, T., Weber, R., Val-Mejias, J. E., et al. (2003). Successful catheter ablation of electrical storm after myocardial infarction. Circulation, 108, 3011–3016.PubMedCrossRef
2.
Zurück zum Zitat Szumowski, L., Sanders, P., Walczak, F., Hocini, M., Jaïs, P., Kepski, R., et al. (2004). Mapping and ablation of polymorphic ventricular tachycardia after myocardial infarction. Journal of the American College of Cardiology, 44, 1700–1706.PubMedCrossRef Szumowski, L., Sanders, P., Walczak, F., Hocini, M., Jaïs, P., Kepski, R., et al. (2004). Mapping and ablation of polymorphic ventricular tachycardia after myocardial infarction. Journal of the American College of Cardiology, 44, 1700–1706.PubMedCrossRef
3.
Zurück zum Zitat Marrouche, N. F., Verma, A., Wazni, O., Schweikert, R., Martin, D. O., Saliba, W., et al. (2004). Mode of initiation and ablation of ventricular fibrillation storms in patients with ischemic cardiomyopathy. Journal of the American College of Cardiology, 43, 1715–1720.PubMedCrossRef Marrouche, N. F., Verma, A., Wazni, O., Schweikert, R., Martin, D. O., Saliba, W., et al. (2004). Mode of initiation and ablation of ventricular fibrillation storms in patients with ischemic cardiomyopathy. Journal of the American College of Cardiology, 43, 1715–1720.PubMedCrossRef
4.
Zurück zum Zitat Marchlinski, F., Garcia, F., Siadatan, A., Sauer, W., Beldner, S., Zado, E., et al. (2005). Ventricular tachycardia/ventricular fibrillation ablation in the setting of ischemic heart disease. Journal of Cardiovascular Electrophysiology, 16, S59–S70.PubMedCrossRef Marchlinski, F., Garcia, F., Siadatan, A., Sauer, W., Beldner, S., Zado, E., et al. (2005). Ventricular tachycardia/ventricular fibrillation ablation in the setting of ischemic heart disease. Journal of Cardiovascular Electrophysiology, 16, S59–S70.PubMedCrossRef
5.
Zurück zum Zitat Kim, Y. H., Xie, F., Yashima, M., Wu, T. J., Valderrábano, M., Lee, M. H., et al. (1999). Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle. Circulation, 100, 1450–1459.PubMed Kim, Y. H., Xie, F., Yashima, M., Wu, T. J., Valderrábano, M., Lee, M. H., et al. (1999). Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle. Circulation, 100, 1450–1459.PubMed
6.
Zurück zum Zitat Pak, H. N., Oh, Y. S., Liu, Y. B., Wu, T. J., Karagueuzian, H. S., Lin, S. F., et al. (2003). Catheter ablation of ventricular fibrillation in rabbit ventricles treated with beta-blockers. Circulation, 108, 3149–3156.PubMedCrossRef Pak, H. N., Oh, Y. S., Liu, Y. B., Wu, T. J., Karagueuzian, H. S., Lin, S. F., et al. (2003). Catheter ablation of ventricular fibrillation in rabbit ventricles treated with beta-blockers. Circulation, 108, 3149–3156.PubMedCrossRef
7.
Zurück zum Zitat Pak, H. N., Kim, Y. H., Lim, H. E., Chou, C. C., Miyauchi, Y., Fang, Y. H., et al. (2006). Role of the posterior papillary muscle and Purkinje potentials in the mechanism of ventricular fibrillation in open chest dogs and swine: effects of catheter ablation. Journal of Cardiovascular Electrophysiology, 17, 777–783.PubMedCrossRef Pak, H. N., Kim, Y. H., Lim, H. E., Chou, C. C., Miyauchi, Y., Fang, Y. H., et al. (2006). Role of the posterior papillary muscle and Purkinje potentials in the mechanism of ventricular fibrillation in open chest dogs and swine: effects of catheter ablation. Journal of Cardiovascular Electrophysiology, 17, 777–783.PubMedCrossRef
8.
Zurück zum Zitat Jalife, J. (2000). Ventricular fibrillation: mechanism of initiation and maintenance. Annual Review of Physiology, 62, 25–50.PubMedCrossRef Jalife, J. (2000). Ventricular fibrillation: mechanism of initiation and maintenance. Annual Review of Physiology, 62, 25–50.PubMedCrossRef
9.
Zurück zum Zitat Berenfeld, O., & Jalife, J. (1998). Purkinje-muscle reentry as a mechanism of polymorphic ventricular arrhythmias in a 3-dimensional model of the ventricles. Circulation Research, 82, 1063–1077.PubMed Berenfeld, O., & Jalife, J. (1998). Purkinje-muscle reentry as a mechanism of polymorphic ventricular arrhythmias in a 3-dimensional model of the ventricles. Circulation Research, 82, 1063–1077.PubMed
10.
Zurück zum Zitat Nogami, A., Sugiyasu, A., Kubota, S., & Kato, K. (2005). Mapping and ablation of idiopathic ventricular fibrillation from the Purkinje system. Heart Rhythm, 2, 646–649.PubMedCrossRef Nogami, A., Sugiyasu, A., Kubota, S., & Kato, K. (2005). Mapping and ablation of idiopathic ventricular fibrillation from the Purkinje system. Heart Rhythm, 2, 646–649.PubMedCrossRef
11.
Zurück zum Zitat Bogun, F., Good, E., Reich, S., Elmouchi, D., Igic, P., Tschopp, D., et al. (2006). Role of Purkinje fibers in post-infarction ventricular tachycardia. Journal of the American College of Cardiology, 48, 2500–2507.PubMedCrossRef Bogun, F., Good, E., Reich, S., Elmouchi, D., Igic, P., Tschopp, D., et al. (2006). Role of Purkinje fibers in post-infarction ventricular tachycardia. Journal of the American College of Cardiology, 48, 2500–2507.PubMedCrossRef
12.
Zurück zum Zitat Liu, X. K., Barrett, R., Packer, D. L., & Asirvatham, S. J. (2008). Successful management of recurrent ventricular tachycardia by electrical isolation of anterolateral papillary muscle. Heart Rhythm, 5, 479–482.PubMedCrossRef Liu, X. K., Barrett, R., Packer, D. L., & Asirvatham, S. J. (2008). Successful management of recurrent ventricular tachycardia by electrical isolation of anterolateral papillary muscle. Heart Rhythm, 5, 479–482.PubMedCrossRef
13.
Zurück zum Zitat Newton, J. C., Smith, W. M., & Ideker, R. E. (2004). Estimated global transmural distribution of activation rate and conduction block during porcine and canine ventricular fibrillation. Circulation Research, 94, 836–842.PubMedCrossRef Newton, J. C., Smith, W. M., & Ideker, R. E. (2004). Estimated global transmural distribution of activation rate and conduction block during porcine and canine ventricular fibrillation. Circulation Research, 94, 836–842.PubMedCrossRef
14.
Zurück zum Zitat Ideker, R. E. (2007). Ventricular fibrillation: how do we put the genie back in the bottle. Heart Rhythm, 4, 665–674.PubMedCrossRef Ideker, R. E. (2007). Ventricular fibrillation: how do we put the genie back in the bottle. Heart Rhythm, 4, 665–674.PubMedCrossRef
Metadaten
Titel
Electrophysiologic and histopathologic findings of the ablation sites for ventricular fibrillation in a patient with ischemic cardiomyopathy
verfasst von
Akihiko Nogami
Shoichi Kubota
Masamitsu Adachi
Osamu Igawa
Publikationsdatum
01.03.2009
Verlag
Springer US
Erschienen in
Journal of Interventional Cardiac Electrophysiology / Ausgabe 2/2009
Print ISSN: 1383-875X
Elektronische ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-008-9312-4

Weitere Artikel der Ausgabe 2/2009

Journal of Interventional Cardiac Electrophysiology 2/2009 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Adipositas-Medikament auch gegen Schlafapnoe wirksam

24.04.2024 Adipositas Nachrichten

Der als Antidiabetikum sowie zum Gewichtsmanagement zugelassene Wirkstoff Tirzepatid hat in Studien bei adipösen Patienten auch schlafbezogene Atmungsstörungen deutlich reduziert, informiert der Hersteller in einer Vorab-Meldung zum Studienausgang.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.