Skip to main content
Erschienen in: Journal of Neuro-Oncology 2/2014

01.11.2014 | Clinical Study

Metastatic meningiomas: an unusual clinical and pathological diagnosis with highly variable outcome

verfasst von: Fabien Forest, Sid-Ali Berremila, Cezar Gyenes, Carole Ginguéné, Radwan Kassir, Abdulrazzaq Sulaiman, Basile Pasquier, Jack Porcheron, Michel Péoc’h

Erschienen in: Journal of Neuro-Oncology | Ausgabe 2/2014

Einloggen, um Zugang zu erhalten

Abstract

Metastatic meningioma is a rare situation. We conducted a retrospective study from our databases and identified cases of metastatic meningioma. We report three presentations of patients with medical history of surgical removal of meningioma presenting several years later a liver tumor with bone metastasis or multiple lung tumors. These observations highlight the difficulty of the clinical and pathological diagnosis and the absence of consideration of metastatic state for histologically “benign” but clinically aggressive meningiomas in the current WHO 2007 classification of meningiomas. We also reviewed published cases of metastatic meningiomas since they are clearly distinguished from haemangiopericytoma.
Literatur
1.
Zurück zum Zitat Louis D (2007) WHO classification of tumours of the central nervous system. IARC, Lyon Louis D (2007) WHO classification of tumours of the central nervous system. IARC, Lyon
2.
Zurück zum Zitat Ather Enam S, Abdulrauf S, Mehta B, Malik G, Mahmood A (1996) Metastasis in meningioma. Acta Neurochir 138:1172–1178CrossRef Ather Enam S, Abdulrauf S, Mehta B, Malik G, Mahmood A (1996) Metastasis in meningioma. Acta Neurochir 138:1172–1178CrossRef
4.
Zurück zum Zitat Kabus D, Sidhu GS, Wieczorek RL, Choi HS (1993) Metastatic meningioma. Hemangiopericytoma or angioblastic meningioma? Am J Surg Pathol 17:1144–1150PubMedCrossRef Kabus D, Sidhu GS, Wieczorek RL, Choi HS (1993) Metastatic meningioma. Hemangiopericytoma or angioblastic meningioma? Am J Surg Pathol 17:1144–1150PubMedCrossRef
5.
Zurück zum Zitat Smith SJ, Boddu S, Macarthur DC (2007) Atypical meningiomas: wHO moved the goalposts? Br J Neurosurg 21:588–592PubMedCrossRef Smith SJ, Boddu S, Macarthur DC (2007) Atypical meningiomas: wHO moved the goalposts? Br J Neurosurg 21:588–592PubMedCrossRef
6.
Zurück zum Zitat Estanislau ES, de Carvalho GTC, Reis BL, de Freitas Barbosa W, Brandão RACS, de Sousa AA et al (2009) Malignant meningioma with extracranial metastases. Arq Neuropsiquiatr 67:730–732PubMedCrossRef Estanislau ES, de Carvalho GTC, Reis BL, de Freitas Barbosa W, Brandão RACS, de Sousa AA et al (2009) Malignant meningioma with extracranial metastases. Arq Neuropsiquiatr 67:730–732PubMedCrossRef
7.
Zurück zum Zitat Lambertz N, Koehler J, Schulte DM, Kuehl H, Wohlschlaeger J, Hense J et al (2011) Multivisceral systemic metastases from an intracranial anaplastic meningioma: a case report and review of literature. Clin Neurol Neurosurg 113:592–595PubMedCrossRef Lambertz N, Koehler J, Schulte DM, Kuehl H, Wohlschlaeger J, Hense J et al (2011) Multivisceral systemic metastases from an intracranial anaplastic meningioma: a case report and review of literature. Clin Neurol Neurosurg 113:592–595PubMedCrossRef
8.
Zurück zum Zitat Asioli S, Senetta R, Maldi E, D’Ambrosio E, Satolli MA, Bussolati G et al (2007) “Benign” metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lung. Virchows Arch 450:591–594PubMedCrossRef Asioli S, Senetta R, Maldi E, D’Ambrosio E, Satolli MA, Bussolati G et al (2007) “Benign” metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lung. Virchows Arch 450:591–594PubMedCrossRef
9.
Zurück zum Zitat Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM (1997) Meningioma grading: an analysis of histologic parameters. Am J Surg Pathol 21:1455–1465PubMedCrossRef Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM (1997) Meningioma grading: an analysis of histologic parameters. Am J Surg Pathol 21:1455–1465PubMedCrossRef
10.
Zurück zum Zitat Figueroa BE, Quint DJ, McKeever PE, Chandler WF (1999) Extracranial metastatic meningioma. Br J Radiol 72:513–516PubMedCrossRef Figueroa BE, Quint DJ, McKeever PE, Chandler WF (1999) Extracranial metastatic meningioma. Br J Radiol 72:513–516PubMedCrossRef
11.
Zurück zum Zitat Mawrin C, Perry A (2010) Pathological classification and molecular genetics of meningiomas. J Neurooncol 99:379–391PubMedCrossRef Mawrin C, Perry A (2010) Pathological classification and molecular genetics of meningiomas. J Neurooncol 99:379–391PubMedCrossRef
12.
Zurück zum Zitat Zhou K, Wang G, Wang Y, Jin H, Yang S, Liu C (2010) The potential involvement of E-cadherin and beta-catenins in meningioma. PLoS One 5(6):e11231PubMedCrossRefPubMedCentral Zhou K, Wang G, Wang Y, Jin H, Yang S, Liu C (2010) The potential involvement of E-cadherin and beta-catenins in meningioma. PLoS One 5(6):e11231PubMedCrossRefPubMedCentral
13.
Zurück zum Zitat Celebre A, Wu MY, Danielson B, Cohen S, Munoz D, Das S, Karamchandani J (2013) Anaplastic meningioma with extensive single-cell infiltration: a potential role for epithelial-mesenchymal transformation in the progression of a meningothelial tumour? Histopathology 62:1111–1114PubMedCrossRef Celebre A, Wu MY, Danielson B, Cohen S, Munoz D, Das S, Karamchandani J (2013) Anaplastic meningioma with extensive single-cell infiltration: a potential role for epithelial-mesenchymal transformation in the progression of a meningothelial tumour? Histopathology 62:1111–1114PubMedCrossRef
14.
Zurück zum Zitat Dogan S, Sahin S, Taskapilioglu O, Aksoy K, Adim S (2004) Multiple metastatic malignant meningioma: a case report. Zentralbl Neurochir 65:141–145PubMedCrossRef Dogan S, Sahin S, Taskapilioglu O, Aksoy K, Adim S (2004) Multiple metastatic malignant meningioma: a case report. Zentralbl Neurochir 65:141–145PubMedCrossRef
15.
Zurück zum Zitat Kano H, Takahashi JA, Katsuki T, Araki N, Oya N, Hiraoka M, Hashimoto N (2007) Stereotactic radiosurgery for atypical and anaplastic meningiomas. J Neurooncol 84:41–47PubMedCrossRef Kano H, Takahashi JA, Katsuki T, Araki N, Oya N, Hiraoka M, Hashimoto N (2007) Stereotactic radiosurgery for atypical and anaplastic meningiomas. J Neurooncol 84:41–47PubMedCrossRef
16.
Zurück zum Zitat Ferguson JM, Flinn J (1995) Intracranial meningioma with hepatic metastases and hypoglycaemia treated by selective hepatic arterial chemo-embolization. Australas Radiol 39:97–99PubMedCrossRef Ferguson JM, Flinn J (1995) Intracranial meningioma with hepatic metastases and hypoglycaemia treated by selective hepatic arterial chemo-embolization. Australas Radiol 39:97–99PubMedCrossRef
18.
Zurück zum Zitat Azene EM, Gai QW, Tabar SP, Morrison AL, Meisenberg B (2008) Metastasis of a histologically benign–appearing meningioma to the iliac bone. J Clin Oncol 26:4688–4690PubMedCrossRef Azene EM, Gai QW, Tabar SP, Morrison AL, Meisenberg B (2008) Metastasis of a histologically benign–appearing meningioma to the iliac bone. J Clin Oncol 26:4688–4690PubMedCrossRef
19.
Zurück zum Zitat Chamberlain MC, Barnholtz-Sloan JS (2011) Medical treatment of recurrent meningiomas. Expert Rev Neurother 11:1425–1432PubMedCrossRef Chamberlain MC, Barnholtz-Sloan JS (2011) Medical treatment of recurrent meningiomas. Expert Rev Neurother 11:1425–1432PubMedCrossRef
20.
Zurück zum Zitat Andric M, Dixit S, Dubey A, Jessup P, Hunn A (2012) Atypical meningiomas–a case series. Clin Neurol Neurosurg 114:699–702PubMedCrossRef Andric M, Dixit S, Dubey A, Jessup P, Hunn A (2012) Atypical meningiomas–a case series. Clin Neurol Neurosurg 114:699–702PubMedCrossRef
21.
Zurück zum Zitat Baek BJ, Shin J-M, Lee CK, Lee JH, Lee KH (2012) Atypical primary meningioma in the nasal septum with malignant transformation and distant metastasis. BMC Cancer 12:275PubMedCrossRefPubMedCentral Baek BJ, Shin J-M, Lee CK, Lee JH, Lee KH (2012) Atypical primary meningioma in the nasal septum with malignant transformation and distant metastasis. BMC Cancer 12:275PubMedCrossRefPubMedCentral
22.
Zurück zum Zitat Celenk F, Erkilic S, Durucu C, Baysal E, Kanlikama M (2012) Late metastasis of an intracranial meningioma to the hard palate. J Craniofac Surg. 23:1912–1914PubMedCrossRef Celenk F, Erkilic S, Durucu C, Baysal E, Kanlikama M (2012) Late metastasis of an intracranial meningioma to the hard palate. J Craniofac Surg. 23:1912–1914PubMedCrossRef
23.
Zurück zum Zitat Chuang H-C, Lee H-C, Cho D-Y (2006) Intracranial malignant meningioma with multiple spinal metastases–a case report and literature review: case report. Spine 31:E1006–E1010PubMedCrossRef Chuang H-C, Lee H-C, Cho D-Y (2006) Intracranial malignant meningioma with multiple spinal metastases–a case report and literature review: case report. Spine 31:E1006–E1010PubMedCrossRef
24.
Zurück zum Zitat Drummond KJ, Bittar RG, Fearnside MR (2007) Metastatic atypical meningioma: case report and review of the literature. J Clin Neurosci 7:69–72CrossRef Drummond KJ, Bittar RG, Fearnside MR (2007) Metastatic atypical meningioma: case report and review of the literature. J Clin Neurosci 7:69–72CrossRef
25.
Zurück zum Zitat Delgado-López PD, Martín-Velasco V, Castilla-Díez JM, Fernández-Arconada O, Corrales-García EM, Galacho-Harnero A et al (2006) Metastatic meningioma to the eleventh dorsal vertebral body: total en bloc spondylectomy. Case report and review of the literature. Neurocirugia 17:240–249PubMed Delgado-López PD, Martín-Velasco V, Castilla-Díez JM, Fernández-Arconada O, Corrales-García EM, Galacho-Harnero A et al (2006) Metastatic meningioma to the eleventh dorsal vertebral body: total en bloc spondylectomy. Case report and review of the literature. Neurocirugia 17:240–249PubMed
26.
Zurück zum Zitat Dmytriw AA, Gullane P, Bartlett E, Perez-Ordonez B, Yu E (2013) Parotid gland metastasis originating from malignant meningioma. Clin Imaging 37:740–743PubMedCrossRef Dmytriw AA, Gullane P, Bartlett E, Perez-Ordonez B, Yu E (2013) Parotid gland metastasis originating from malignant meningioma. Clin Imaging 37:740–743PubMedCrossRef
27.
Zurück zum Zitat Doxtader EE, Butts SC, Holsapple JW, Fuller CE (2009) Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. Pediatr Dev Pathol 12:244–248PubMedCrossRef Doxtader EE, Butts SC, Holsapple JW, Fuller CE (2009) Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. Pediatr Dev Pathol 12:244–248PubMedCrossRef
28.
Zurück zum Zitat Erman T, Hanta I, Haciyakupoğlu S, Zorludemir S, Zeren H, Göçer AI (2005) Huge bilateral pulmonary and pleural metastasis from intracranial meningioma: a case report and review of the literature. J Neurooncol 74:179–181PubMedCrossRef Erman T, Hanta I, Haciyakupoğlu S, Zorludemir S, Zeren H, Göçer AI (2005) Huge bilateral pulmonary and pleural metastasis from intracranial meningioma: a case report and review of the literature. J Neurooncol 74:179–181PubMedCrossRef
29.
Zurück zum Zitat Fabi A, Nuzzo C, Vidiri A, Ciccarese M, Felici A, Cattani F et al (2006) Bone and lung metastases from intracranial meningioma. Anticancer Res 26:3835–3837PubMed Fabi A, Nuzzo C, Vidiri A, Ciccarese M, Felici A, Cattani F et al (2006) Bone and lung metastases from intracranial meningioma. Anticancer Res 26:3835–3837PubMed
30.
Zurück zum Zitat Fulkerson DH, Horner TG, Hattab EM (2008) Histologically benign intraventricular meningioma with concurrent pulmonary metastasis: case report and review of the literature. Clin Neurol Neurosurg 110:416–419PubMedCrossRef Fulkerson DH, Horner TG, Hattab EM (2008) Histologically benign intraventricular meningioma with concurrent pulmonary metastasis: case report and review of the literature. Clin Neurol Neurosurg 110:416–419PubMedCrossRef
31.
Zurück zum Zitat Gladin CR, Salsano E, Menghi F, Grisoli M, Ghielmetti F, Milanesi I et al (2007) Loss of heterozygosity studies in extracranial metastatic meningiomas. J Neurooncol 85:81–85PubMedCrossRef Gladin CR, Salsano E, Menghi F, Grisoli M, Ghielmetti F, Milanesi I et al (2007) Loss of heterozygosity studies in extracranial metastatic meningiomas. J Neurooncol 85:81–85PubMedCrossRef
32.
Zurück zum Zitat Kim H, Jung T-Y, Kim I-Y, Lee J-K (2012) Two cases of primary osteolytic intraosseous meningioma of the skull metastasizing to whole skull and the spine. J Korean Neurosurg Soc. 51:151–154PubMedCrossRefPubMedCentral Kim H, Jung T-Y, Kim I-Y, Lee J-K (2012) Two cases of primary osteolytic intraosseous meningioma of the skull metastasizing to whole skull and the spine. J Korean Neurosurg Soc. 51:151–154PubMedCrossRefPubMedCentral
33.
Zurück zum Zitat Kovoor JME, Jayakumar PN, Srikanth SG, Indira B, Devi MG (2002) Solitary pulmonary metastasis from intracranial meningiothelial meningioma. Australas Radiol 46:65–68PubMedCrossRef Kovoor JME, Jayakumar PN, Srikanth SG, Indira B, Devi MG (2002) Solitary pulmonary metastasis from intracranial meningiothelial meningioma. Australas Radiol 46:65–68PubMedCrossRef
34.
Zurück zum Zitat Kros JM, Cella F, Bakker SL, Paz Y, Geuze D, Egeler RM (2000) Papillary meningioma with pleural metastasis: case report and literature review. Acta Neurol Scand 102:200–202PubMedCrossRef Kros JM, Cella F, Bakker SL, Paz Y, Geuze D, Egeler RM (2000) Papillary meningioma with pleural metastasis: case report and literature review. Acta Neurol Scand 102:200–202PubMedCrossRef
35.
Zurück zum Zitat Lanfranchi M, Nikpoor N (2013) Detection of meningioma metastasis to liver and lung using somatostatin receptor scintigraphy. Clin Nucl Med 38:668–670PubMedCrossRef Lanfranchi M, Nikpoor N (2013) Detection of meningioma metastasis to liver and lung using somatostatin receptor scintigraphy. Clin Nucl Med 38:668–670PubMedCrossRef
36.
37.
Zurück zum Zitat Lee Y–Y, Wen-Wei Hsu R, Huang T-J, Hsueh S, Wang J-Y (2002) Metastatic meningioma in the sacrum: a case report. Spine 27:E100–E103PubMedCrossRef Lee Y–Y, Wen-Wei Hsu R, Huang T-J, Hsueh S, Wang J-Y (2002) Metastatic meningioma in the sacrum: a case report. Spine 27:E100–E103PubMedCrossRef
38.
Zurück zum Zitat Moubayed SP, Guertin L, Lambert C, Desrochers P, Nehmé J, Coulombe G (2013) Successful treatment of anaplastic meningioma metastatic to cervical lymph nodes. Head Neck 35:E115–E118PubMedCrossRef Moubayed SP, Guertin L, Lambert C, Desrochers P, Nehmé J, Coulombe G (2013) Successful treatment of anaplastic meningioma metastatic to cervical lymph nodes. Head Neck 35:E115–E118PubMedCrossRef
39.
Zurück zum Zitat Nakayama Y, Horio H, Horiguchi S, Hato T (2013) Pulmonary and pleural metastases from benign meningeal meningioma: a case report. Ann Thorac Cardiovasc Surg Nakayama Y, Horio H, Horiguchi S, Hato T (2013) Pulmonary and pleural metastases from benign meningeal meningioma: a case report. Ann Thorac Cardiovasc Surg
40.
Zurück zum Zitat Pinsker MO, Buhl R, Hugo H–H, Mehdorn HM (2005) Metastatic meningioma WHO grade II of the cervical spine: case report and review of the literature. Zentralbl Neurochir 66:35–38PubMedCrossRef Pinsker MO, Buhl R, Hugo H–H, Mehdorn HM (2005) Metastatic meningioma WHO grade II of the cervical spine: case report and review of the literature. Zentralbl Neurochir 66:35–38PubMedCrossRef
41.
Zurück zum Zitat Pramesh C, Saklani AP, Pantvaidya GH, Heroor AA, Naresh K, Sharma S et al (2003) Benign metastasizing meningioma. Jpn J Clin Oncol 33:86PubMedCrossRef Pramesh C, Saklani AP, Pantvaidya GH, Heroor AA, Naresh K, Sharma S et al (2003) Benign metastasizing meningioma. Jpn J Clin Oncol 33:86PubMedCrossRef
42.
Zurück zum Zitat Rampurwala M, Pazooki M, Schauer P (2011) Delayed hepatic metastasis from a benign fibroblastic meningioma thirty-one years after surgical resection of the intracranial tumor. J Clin Oncol 29:e214–e215PubMedCrossRef Rampurwala M, Pazooki M, Schauer P (2011) Delayed hepatic metastasis from a benign fibroblastic meningioma thirty-one years after surgical resection of the intracranial tumor. J Clin Oncol 29:e214–e215PubMedCrossRef
43.
Zurück zum Zitat Sabet A, Ahmadzadehfar H, Herrlinger U, Wilinek W, Biersack H-J, Ezziddin S (2011) Successful radiopeptide targeting of metastatic anaplastic meningioma: case report. Radiat Oncol 6:94PubMedCrossRefPubMedCentral Sabet A, Ahmadzadehfar H, Herrlinger U, Wilinek W, Biersack H-J, Ezziddin S (2011) Successful radiopeptide targeting of metastatic anaplastic meningioma: case report. Radiat Oncol 6:94PubMedCrossRefPubMedCentral
44.
Zurück zum Zitat Sujit Kumar GS, Chacko G, Chacko AG, Haran RP (2009) Multiple extracranial metastases from intradiploic meningioma. Neurol India 57:96–97PubMedCrossRef Sujit Kumar GS, Chacko G, Chacko AG, Haran RP (2009) Multiple extracranial metastases from intradiploic meningioma. Neurol India 57:96–97PubMedCrossRef
45.
Zurück zum Zitat Taieb G, Campello C, Renard D, El Fertit H, Joujoux JM, Savin C et al (2011) Multifocal extracranial meningioma metastases. Arch Neurol 68:388–389PubMed Taieb G, Campello C, Renard D, El Fertit H, Joujoux JM, Savin C et al (2011) Multifocal extracranial meningioma metastases. Arch Neurol 68:388–389PubMed
46.
Zurück zum Zitat Wang Z, Kong M, Li J, Xiao W, Zheng S (2011) Intraspinal rhabdoid meningioma metastasis to the liver. J Clin Neurosci 18:714–716PubMedCrossRef Wang Z, Kong M, Li J, Xiao W, Zheng S (2011) Intraspinal rhabdoid meningioma metastasis to the liver. J Clin Neurosci 18:714–716PubMedCrossRef
47.
Zurück zum Zitat Williamson BE, Stanton CA, Levine EA (2001) Chest wall metastasis from recurrent meningioma. Am Surg 67:966–968PubMed Williamson BE, Stanton CA, Levine EA (2001) Chest wall metastasis from recurrent meningioma. Am Surg 67:966–968PubMed
Metadaten
Titel
Metastatic meningiomas: an unusual clinical and pathological diagnosis with highly variable outcome
verfasst von
Fabien Forest
Sid-Ali Berremila
Cezar Gyenes
Carole Ginguéné
Radwan Kassir
Abdulrazzaq Sulaiman
Basile Pasquier
Jack Porcheron
Michel Péoc’h
Publikationsdatum
01.11.2014
Verlag
Springer US
Erschienen in
Journal of Neuro-Oncology / Ausgabe 2/2014
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-014-1567-2

Weitere Artikel der Ausgabe 2/2014

Journal of Neuro-Oncology 2/2014 Zur Ausgabe

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Frühe Alzheimertherapie lohnt sich

25.04.2024 AAN-Jahrestagung 2024 Nachrichten

Ist die Tau-Last noch gering, scheint der Vorteil von Lecanemab besonders groß zu sein. Und beginnen Erkrankte verzögert mit der Behandlung, erreichen sie nicht mehr die kognitive Leistung wie bei einem früheren Start. Darauf deuten neue Analysen der Phase-3-Studie Clarity AD.

Viel Bewegung in der Parkinsonforschung

25.04.2024 Parkinson-Krankheit Nachrichten

Neue arznei- und zellbasierte Ansätze, Frühdiagnose mit Bewegungssensoren, Rückenmarkstimulation gegen Gehblockaden – in der Parkinsonforschung tut sich einiges. Auf dem Deutschen Parkinsonkongress ging es auch viel um technische Innovationen.

Demenzkranke durch Antipsychotika vielfach gefährdet

23.04.2024 Demenz Nachrichten

Wenn Demenzkranke aufgrund von Symptomen wie Agitation oder Aggressivität mit Antipsychotika behandelt werden, sind damit offenbar noch mehr Risiken verbunden als bislang angenommen.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.