Erschienen in:
01.09.2007
Molecular profiling in breast cancer
verfasst von:
Shannon R. Morris, Lisa A. Carey
Erschienen in:
Reviews in Endocrine and Metabolic Disorders
|
Ausgabe 3/2007
Einloggen, um Zugang zu erhalten
Abstract
Molecular profiling has provided biological evidence for the heterogeneity of breast cancer through the identification of intrinsic subtypes like Luminal A, Luminal B, HER2+/ER− and basal-like. It has also led to the development of clinically applicable gene expression-based prognostic panels like the Mammaprint® and Oncotype Dx™. The increasingly sophisticated understanding allowed by this and similar technology promises future individualized therapy.