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14.08.2017 | Sleep Breathing Physiology and Disorders • Original Article

Non-REM sleep-disordered breathing affects performance on the psychomotor vigilance task

verfasst von: Takuro Kitamura, Soichiro Miyazaki, Hiroshi Kadotani, Takashi Kanemura, Harun Bin Sulaiman, Shoko Takeuchi, Takahisa Tabata, Hideaki Suzuki

Erschienen in: Sleep and Breathing | Ausgabe 2/2018

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Abstract

Purpose

Although many studies have investigated the clinical importance of sleep apnea on rapid eye movement (REM) and non-REM (NREM) sleep, the relationship between behavioral performance and apneic events during different sleep phases remains unclear. In the present study, we sought to investigate the effect of sleep phase fragmentation due to sleep-disordered breathing (SDB) during REM and NREM on the vigilance and sustainability of attention based on psychomotor vigilance task (PVT) performance.

Methods

From a pool of subjects who underwent consecutive diagnostic polysomnography (PSG) for obstructive sleep apnea, 163 adult subjects with both REM and NREM sleep ≥ 30 min were enrolled for our study and performed a standardized 10-min PVT. The main outcome variables of the PVT were mean reaction time (RT), PVT Lapse count, and the slope of the reciprocal RT. Subjective sleepiness was measured using the Epworth Sleepiness Scale (ESS).

Results

After multivariate linear regression analysis with adjustment for age, sex, body mass index, and the apnea-hypopnea index (AHI) of the counterpart sleep phase, we found that AHI during NREM (AHI_NREM) compared to AHI during REM (AHI_REM) was significantly associated with PVT lapses.

Conclusions

Our results suggest that SDB during NREM has a significant impact on vigilance lapses compared to that of REM.

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Titel: Non-REM sleep-disordered breathing affects performance on the psychomotor vigilance task
verfasst von: Takuro Kitamura
Soichiro Miyazaki
Hiroshi Kadotani
Takashi Kanemura
Harun Bin Sulaiman
Shoko Takeuchi
Takahisa Tabata
Hideaki Suzuki
Publikationsdatum: 14.08.2017
Verlag: Springer International Publishing
Erschienen in: Sleep and Breathing / Ausgabe 2/2018
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-017-1553-y

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Non-REM sleep-disordered breathing affects performance on the psychomotor vigilance task