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Targeted Oncology
Erschienen in: Targeted Oncology 3/2010

01.09.2010 | Review

Molecular markers in gliomas: impact for the clinician

verfasst von: Silvia Hofer, Andrew B. Lassman

Erschienen in: Targeted Oncology | Ausgabe 3/2010

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Abstract

Over the last decade, understanding of glioma on a molecular level has greatly expanded. However, optimal incorporation of molecular markers into clinical care is controversial. We briefly review the potential utility of molecular stratification in refining histologic diagnosis, prognosis, and treatment decisions, focussing on 1p/19q co-deletion, MGMT promoter methylation, EGFR mutations, and IDH mutation. The most recently discovered IDH mutation is a striking example of a rapid implementation of a molecular marker for prognostication into common clinical use.
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Metadaten
Titel
Molecular markers in gliomas: impact for the clinician
verfasst von
Silvia Hofer
Andrew B. Lassman
Publikationsdatum
01.09.2010
Verlag
Springer-Verlag
Erschienen in
Targeted Oncology / Ausgabe 3/2010
Print ISSN: 1776-2596
Elektronische ISSN: 1776-260X
DOI
https://doi.org/10.1007/s11523-010-0157-2

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