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Obesity Surgery

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01.09.2013 | Review

Challenges in the Optimisation of Post-operative Pain Management with Opioids in Obese Patients: a Literature Review

verfasst von: C. Lloret-Linares, A. Lopes, X. Declèves, A. Serrie, S. Mouly, J.-F. Bergmann, S. Perrot

Erschienen in: Obesity Surgery | Ausgabe 9/2013

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Abstract

An increasing number of obese patients are undergoing surgery, particularly bariatric and orthopaedic surgery. The physiological differences between obese and normal-weight subjects may modify not only anaesthetic requirements during surgery but also post-operative analgesic management, raising a number of challenges in a critical period. In this review, we analyse studies of post-operative pain management with opioids in obese subjects. We discuss the genetic factors common to pain and obesity and the factors potentially modifying opioid pharmacokinetics and pharmacodynamics in obese patients, and we analyse the overall efficacy and safety of opioids for pain management during the post-operative period in obese patients. Both modifications to surgical methods and additional analgesic treatments to decrease the requirement for opioids may improve early rehabilitation and quality of care and reduce adverse effects in obese patients.

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Titel: Challenges in the Optimisation of Post-operative Pain Management with Opioids in Obese Patients: a Literature Review
verfasst von: C. Lloret-Linares
A. Lopes
X. Declèves
A. Serrie
S. Mouly
J.-F. Bergmann
S. Perrot
Publikationsdatum: 01.09.2013
Verlag: Springer US
Erschienen in: Obesity Surgery / Ausgabe 9/2013
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-013-0998-8

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