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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 5/2014

01.05.2014 | RHINITIS (JJ OPPENHEIMER AND J CORREN, SECTION EDITORS)

Cytokine Profiles in Allergic Rhinitis

verfasst von: Guy Scadding

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 5/2014

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Abstract

Allergic rhinitis, particularly seasonal allergic rhinitis, is considered a classic Th2-mediated disease, with important contributions to pathology by interleukins 4, 5 and 13. As such, allergic rhinitis is an excellent model for studying allergic inflammation, with findings potentially relevant to the mechanism of lower airways inflammation seen in allergic asthma. However, recent evidence has revealed roles for additional non-Th2 cytokines in asthma, including IL-17 family cytokines and epithelial-derived cytokines. Additionally, putative roles for epithelial-derived cytokines and innate lymphoid cells have been described in chronic rhinosinusitis with nasal polyps. Here, evidence for the involvement of different cytokines and cytokine groups in allergic rhinitis is considered.
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Metadaten
Titel
Cytokine Profiles in Allergic Rhinitis
verfasst von
Guy Scadding
Publikationsdatum
01.05.2014
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 5/2014
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-014-0435-7

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