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Current HIV/AIDS Reports

Erschienen in:

18.10.2017 | Complications of Antiretroviral Therapy (G McComsey, Section Editor)

The Fat of the Matter: Obesity and Visceral Adiposity in Treated HIV Infection

verfasst von: Jordan E. Lake

Erschienen in: Current HIV/AIDS Reports | Ausgabe 6/2017

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Abstract

Purpose of Review

The aim of this review is to summarize knowledge of the prevalence, relevant physiology, and consequences of obesity and visceral adiposity in HIV-infected adults, including highlighting gaps in current knowledge and future research directions.

Recent Findings

Similar to the general population, obesity prevalence is increasing among HIV-infected persons, and obesity and visceral adiposity are associated with numerous metabolic and inflammatory sequelae. However, HIV- and antiretroviral therapy (ART)-specific factors may contribute to fat gain and fat quality in treated HIV infection, particularly to the development of visceral adiposity, and sex differences may exist.

Summary

Obesity and visceral adiposity commonly occur in HIV-infected persons and have significant implications for morbidity and mortality. Future research should aim to better elucidate the HIV- and ART-specific contributors to obesity and visceral adiposity in treated HIV infection, with the goal of developing targeted therapies for the prevention and treatment of obesity and visceral adiposity in the modern ART era.

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Titel: The Fat of the Matter: Obesity and Visceral Adiposity in Treated HIV Infection
verfasst von: Jordan E. Lake
Publikationsdatum: 18.10.2017
Verlag: Springer US
Erschienen in: Current HIV/AIDS Reports / Ausgabe 6/2017
Print ISSN: 1548-3568
Elektronische ISSN: 1548-3576
DOI: https://doi.org/10.1007/s11904-017-0368-6

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