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Erschienen in: Current Oncology Reports 6/2022

07.03.2022 | Neuroendocrine Neoplasms (NS Reed, Section Editor)

Neuroendocrine Tumors: a Relevant Clinical Update

verfasst von: Emma N. Rizen, Alexandria T. Phan

Erschienen in: Current Oncology Reports | Ausgabe 6/2022

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Abstract

Purpose of Review

The field of neuroendocrine oncology has changed much since the time of Oberndorfer first described and coined the term carcinoid. The purpose of this review is to summarize recent findings and highlight clinically relevant updates in the management of NENs, particularly those that are practice changing.

Recent Findings

Neuroendocrine tumors (NETs) have replaced carcinoid tumor, for the most part. The classification of neuroendocrine neoplasms (NENs) improved, and the epidemiological understanding of this disease group also expanded with global collaborations and maturation of large tumor registries. Clarity in the utility of some NET biomarkers continues to be evolving. Knowledge of molecular drivers of tumorigenesis increases, and scientific/technological advancements lead the way to multiple drug approvals for the treatment of advanced NETs.

Summary

The incidence and prevalence of NENs continue to increase, and patients are living longer. Better understanding of molecular drivers and further understanding of the role of immunotherapy in NENs will further elevate the level of care and transform care for all patients with NENs.
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Metadaten
Titel
Neuroendocrine Tumors: a Relevant Clinical Update
verfasst von
Emma N. Rizen
Alexandria T. Phan
Publikationsdatum
07.03.2022
Verlag
Springer US
Erschienen in
Current Oncology Reports / Ausgabe 6/2022
Print ISSN: 1523-3790
Elektronische ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-022-01217-z

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