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Erschienen in: Current Oncology Reports 7/2022

22.03.2022 | Leukemia (A Aguayo, Section Editor)

Antibiotic Management of Patients with Hematologic Malignancies: From Prophylaxis to Unusual Infections

verfasst von: Francisco Moreno-Sanchez, Brenda Gomez-Gomez

Erschienen in: Current Oncology Reports | Ausgabe 7/2022

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Abstract

Purpose of Review

Patients with hematological malignancies are recognized for their high susceptibility and increased risk of developing infections associated with immunosuppression that can be caused by the infection itself or by the treatments that condition a decrease in the humoral and T lymphocyte response, so this review attempts to gather the main bacterial, viral, parasitic, and fungal agents that affect them and give recommendations for their approach and diagnosis.

Recent Findings

In recent years, with the discovery and use of new therapies including immunological and targeted treatments, it has been possible to improve the survival and response of patients with hematological malignancies; however, antimicrobial resistance has also increased; we have faced new and unknown microorganisms, such as the SARS-CoV-2 that caused the COVID-19 pandemic in the past year, and therefore, new risks and more severe infections are presented.

Summary

We present a review of the different circumstances where hematological malignancies increased the risk of infections and which microorganisms affect these patients, their characteristics, and the suggested prophylaxis.
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Metadaten
Titel
Antibiotic Management of Patients with Hematologic Malignancies: From Prophylaxis to Unusual Infections
verfasst von
Francisco Moreno-Sanchez
Brenda Gomez-Gomez
Publikationsdatum
22.03.2022
Verlag
Springer US
Erschienen in
Current Oncology Reports / Ausgabe 7/2022
Print ISSN: 1523-3790
Elektronische ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-022-01226-y

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