Erschienen in:
22.03.2022 | Geriatric Oncology (L Balducci, Section Editor)
Treatment of Metastatic Melanoma in the Elderly
verfasst von:
Rino S. Seedor, Marlana Orloff
Erschienen in:
Current Oncology Reports
|
Ausgabe 7/2022
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Abstract
Purpose of Review
This study aims to review the clinical experience of melanoma treatments in patients with advanced age.
Recent Findings
During the last decade, the treatment paradigm for melanoma has changed dramatically with the use of checkpoint inhibitors, oncolytic viruses, and targeted therapies. We reviewed both the clinical trial and real-world experience of these therapies in patients of advanced age, and discuss how a personalized approach should be taken for these patients with consideration of incidence and management of side effects.
Summary
Although special consideration should be taken, immunotherapy, oncolytic viruses, and targeted therapy have shown efficacy and tolerability in older patients with melanoma.