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Current Psychiatry Reports
Erschienen in: Current Psychiatry Reports 10/2016

01.10.2016 | Anxiety Disorders (A Pelissolo, Section Editor)

Can Neuroimaging Provide Reliable Biomarkers for Obsessive-Compulsive Disorder? A Narrative Review

verfasst von: Ilana Frydman, Juliana B. de Salles Andrade, Paula Vigne, Leonardo F. Fontenelle

Erschienen in: Current Psychiatry Reports | Ausgabe 10/2016

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Abstract

In this integrative review, we discuss findings supporting the use neuroimaging biomarkers in the diagnosis and treatment of obsessive-compulsive disorder (OCD). To do so, we have selected the most recent studies that attempted to identify the underlying pathogenic process associated with OCD and whether they provide useful information to predict clinical features, natural history or treatment responses. Studies using functional magnetic resonance (fMRI), voxel-based morphometry (VBM), diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (1H MRS) in OCD patients are generally supportive of an expanded version of the earlier cortico-striatal-thalamus-cortical (CSTC) model of OCD. Although it is still unclear whether this information will be incorporated into the daily clinical practice (due to current conceptual approaches to mental illness), statistical techniques, such as pattern recognition methods, appear promising in identifying OCD patients and predicting their outcomes.
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Metadaten
Titel
Can Neuroimaging Provide Reliable Biomarkers for Obsessive-Compulsive Disorder? A Narrative Review
verfasst von
Ilana Frydman
Juliana B. de Salles Andrade
Paula Vigne
Leonardo F. Fontenelle
Publikationsdatum
01.10.2016
Verlag
Springer US
Erschienen in
Current Psychiatry Reports / Ausgabe 10/2016
Print ISSN: 1523-3812
Elektronische ISSN: 1535-1645
DOI
https://doi.org/10.1007/s11920-016-0729-7

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