Erschienen in:
01.08.2019 | Anxiety Disorders (A Pelissolo, Section Editor)
Obsessive-Compulsive Symptoms in Schizophrenia: an Up-To-Date Review of Literature
verfasst von:
Chloé Tezenas du Montcel, Antoine Pelissolo, Franck Schürhoff, Baptiste Pignon
Erschienen in:
Current Psychiatry Reports
|
Ausgabe 8/2019
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Abstract
Purpose of Review
This review will aim to summarize the current body of epidemiological, clinical and therapeutic knowledge concerning specific co-occurrence of obsessive-compulsive symptoms (OCSs) and schizophrenia spectrum disorder.
Recent Findings
Almost 30% of the patients with schizophrenia display OCS, and three main contexts of emergence are identified: prodromal symptoms of schizophrenia, co-occurrence of OCS and schizophrenia and antipsychotics-induced OCS. Recent clinical studies show that patients with SZ and OCS have more severe psychotic and depressive symptoms, higher suicidality and lower social functioning. A recent cognitive investigation found that OCS and delusions share specific metacognitive profiles, particularly through a heightened need to control thoughts. Finally, a recent cross-sectional study of clozapine-induced OCS found a dose-response relationship between clozapine and OCS.
Summary
OCS appeared reliably as linked to poorer outcomes among patients with schizophrenia. However, the specific clinical value of OCS among other prodromal symptoms of schizophrenia remains unknown.