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Forensic Science, Medicine and Pathology

Erschienen in:

01.06.2009 | Review

Y chromosome STR typing in crime casework

verfasst von: Lutz Roewer

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 2/2009

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Abstract

Since the beginning of the nineties the field of forensic Y chromosome analysis has been successfully developed to become commonplace in laboratories working in crime casework all over the world. The ability to identify male-specific DNA renders highly variable Y-chromosomal polymorphisms, the STR sequences, an invaluable addition to the standard panel of autosomal loci used in forensic genetics. The male-specificity makes the Y chromosome especially useful in cases of male/female cell admixture, namely in sexual assault cases. On the other hand, the haploidy and patrilineal inheritance complicates the interpretation of a Y-STR match, because male relatives share for several generations an identical Y-STR profile. Since paternal relatives tend to live in the geographic and cultural territory of their ancestors, the Y chromosome analysis has a potential to make inferences on the population of origin of a given DNA profile. This review addresses the fields of application of Y chromosome haplotyping, the interpretation of results, databasing efforts and population genetics aspects.

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Titel: Y chromosome STR typing in crime casework
verfasst von: Lutz Roewer
Publikationsdatum: 01.06.2009
Verlag: Humana Press Inc
Erschienen in: Forensic Science, Medicine and Pathology / Ausgabe 2/2009
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI: https://doi.org/10.1007/s12024-009-9089-5

Springer Medizin

Y chromosome STR typing in crime casework

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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