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Erschienen in: Neurocritical Care 2/2012

01.10.2012 | Original Article

The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics

verfasst von: Paul E. Marik, Alisha Young, Steve Sibole, Alex Levitov

Erschienen in: Neurocritical Care | Ausgabe 2/2012

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Abstract

Background

Airway pressure release ventilation (APRV) is an alternative approach to the low-tidal volume “open-lung” ventilation strategy. APRV is associated with a higher mean airway pressure than conventional ventilation and has therefore not been evaluated in patients with acute neurological injuries.

Methods

Case report.

Results

We report a patient with severe progressive hypoxemia following a subarachnoid hemorrhage who was converted from pressure-controlled mechanical ventilation to APRV. This change in ventilatory mode was associated with a significant improvement in oxygenation and alveolar ventilation with an associated increase in cerebral blood flow and a negligible increase in intracranial pressure.

Conclusion

APRV may safely be applied to neurocritically ill patients, and that this mode of ventilation may increase cerebral blood flow without increasing intracranial pressure.
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Metadaten
Titel
The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics
verfasst von
Paul E. Marik
Alisha Young
Steve Sibole
Alex Levitov
Publikationsdatum
01.10.2012
Verlag
Humana Press Inc
Erschienen in
Neurocritical Care / Ausgabe 2/2012
Print ISSN: 1541-6933
Elektronische ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-012-9739-4

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