Erschienen in:
01.10.2012 | Original Article
The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics
verfasst von:
Paul E. Marik, Alisha Young, Steve Sibole, Alex Levitov
Erschienen in:
Neurocritical Care
|
Ausgabe 2/2012
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Abstract
Background
Airway pressure release ventilation (APRV) is an alternative approach to the low-tidal volume “open-lung” ventilation strategy. APRV is associated with a higher mean airway pressure than conventional ventilation and has therefore not been evaluated in patients with acute neurological injuries.
Results
We report a patient with severe progressive hypoxemia following a subarachnoid hemorrhage who was converted from pressure-controlled mechanical ventilation to APRV. This change in ventilatory mode was associated with a significant improvement in oxygenation and alveolar ventilation with an associated increase in cerebral blood flow and a negligible increase in intracranial pressure.
Conclusion
APRV may safely be applied to neurocritically ill patients, and that this mode of ventilation may increase cerebral blood flow without increasing intracranial pressure.