Erschienen in:
01.12.2014 | Case Report
Metastatic Leiomyosarcoma to the Pancreas Presenting as a Massive Upper Gastrointestinal Hemorrhage
verfasst von:
Christian Andrade, Jon Finan, Prasad Kulkarni
Erschienen in:
Journal of Gastrointestinal Cancer
|
Sonderheft 1/2014
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Excerpt
Leiomyosarcomas are rare, comprising only 0.1 % of all primary pancreatic malignancies [
1]. They originate from smooth muscle and are most commonly found within the stomach and small intestine as well as in the large intestine, uterus, and retroperitoneum [
2]. Leiomyosarcomas have a predilection for hematogenous spread with the liver and lungs being the most common sites of metastasis. Diagnosis requires immunohistochemical confirmation with positivity most commonly seen for smooth muscle actin (SMA), caldesmon, vimentin, and desmin. In a recent review, only 25 cases of solitary metastatic leiomyosarcomas were found in the literature [
3]. …