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Indian Journal of Pediatrics

Erschienen in:

01.08.2013 | Original Article

Prevalence and Risk Factors for Hepatitis C Virus, Hepatitis B Virus, and Human Immunodeficiency Virus in Transfused Children in Kinshasa

verfasst von: M. Katabuka, M. E. Mafuta, A. M. Ngoma, P. Mutombo Beya, S. Yuma, L. Aketi, K. P. Kayembe, J. R. Gini

Erschienen in: Indian Journal of Pediatrics | Ausgabe 8/2013

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Abstract

Objective

To determine seroprevalence of hepatitis C virus (HCV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) and associated factors among transfused children.

Methods

A multicenter cross-sectional study of transfused children aged between 18 mo and 13 y old was conducted in 4 hospitals in Kinshasa. Blood samples were collected for the detection of Hepatitis B surface antigen (HBsAg) and antibodies to HCV, HIV 1and 2.

Results

A total of 177 (47.7 %) boys and 194 (52.3 %) girls participated in the study. The median age was 59.5 mo (Interquartile range IQR = 60.6). The prevalence rates of HCV, HBV, and HIV infection were 13.5 %, 1.6 %, and 1.3 %, respectively. Frequency of transfusion events were significantly associated with HCV (p < 0.001) and HIV (p < 0.05) infections.

Conclusions

HCV infection was by far more frequently identified than HBV and HIV infections among Congolese transfused children. Frequency of transfusion events was the only significant risk factor associated with HCV and HIV infections but not for HBV.

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Titel: Prevalence and Risk Factors for Hepatitis C Virus, Hepatitis B Virus, and Human Immunodeficiency Virus in Transfused Children in Kinshasa
verfasst von: M. Katabuka
M. E. Mafuta
A. M. Ngoma
P. Mutombo Beya
S. Yuma
L. Aketi
K. P. Kayembe
J. R. Gini
Publikationsdatum: 01.08.2013
Verlag: Springer India
Erschienen in: Indian Journal of Pediatrics / Ausgabe 8/2013
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-012-0899-1

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Prevalence and Risk Factors for Hepatitis C Virus, Hepatitis B Virus, and Human Immunodeficiency Virus in Transfused Children in Kinshasa