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Indian Journal of Pediatrics

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01.01.2014 | Original Article

Evaluation of Synovial Inflammation in Juvenile Idiopathic Arthritis by Power Color Doppler and Spectral Doppler Ultrasonography

verfasst von: Sanjeev Ranjan, Afsana Jahan, Tribhuvan Pal Yadav, Namrita Sachdev, Vivek Dewan, Shweta Singh

Erschienen in: Indian Journal of Pediatrics | Ausgabe 1/2014

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Abstract

Objectives

To compare Power Color Doppler and Spectral Doppler ultrasonography indices (Resistive index and color fraction) in cases of Juvenile Idiopathic Arthritis (JIA) with healthy controls and evaluate their correlation with clinical and laboratory parameters.

Methods

A cross sectional study was done over a period of 16 mo. Thirty patients of JIA and 30 age and sex matched healthy children were enrolled. Swelling and tenderness scores were evaluated and hemoglobin, total leukocyte count, erythrocyte sedimentation rate and C-reactive protein were done. A total of 112 diseased joints and 135 healthy joints were evaluated by USG by the same radiologist, and color fraction and RI were recorded.

Results

Statistically significant higher color fraction and lower RI (Resistive Index) were found in diseased joints as compared to healthy joints. Also the value of color fraction increased significantly with increasing grade of tenderness and RI decreased significantly with increasing grade of swelling.

Conclusions

Power Color Doppler and Spectral Doppler ultrasonography (USG) indices (RI and color fraction) are significantly different in JIA patients. These might find a place in early diagnosis, monitoring of disease activity and response to therapy in JIA patients.

Cassidy JT, Petty RE. Chronic arthritis in children. In: Cassidy JT, Petty RE, Laxer RM, Lindsley CB, eds. Textbook of Pediatric Rheumatology. 5th ed. USA: Elsevier Saunder; 2005. pp. 206–60.

Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001. J Rheumatol. 2004;31:390–2.PubMed

Giannini EH, Ruperto N, Ravelli A, Lovell DJ, Felson DT, Martini A. Preliminary definition of improvement in juvenile idiopathic arthritis. Arthritis Rheum. 1997;40:1202–9.PubMed

Terslev L, Torp-Pedersen S, Savnik A, von der Recke P, Qvistgaard E, Danneskiold-Samsøe B, et al. Doppler ultrasound and magnetic resonance imaging of synovial inflammation of the hand in rheumatoid arthritis: A comparative study. Arthritis Rheum. 2003;48:2434–41.

Varsamidis K, Varsamidou E, Tjetjis V, Mavropoulos G. Doppler sonography in assessing disease activity in rheumatoid arthritis. Ultrasound Med Biol. 2005;31:739–43.PubMedCrossRef

Rubin JM, Adler RS, Fowlkes JB, Spratt S, Pallister JE, Chen JF, et al. Fractional moving blood volume: Estimation with power Doppler US. Radiology. 1995;197:183–90.

Goldenstein C, McCauley R, Troy M, Schaller JG, Szer IS. Ultrasonography in the evaluation of wrist swelling in children. J Rheumatol. 1989;16:1079–87.PubMed

Newman JS, Adler RS, Bude RO, Rubin JM. Detection of soft-tissue hyperemia: Value of power Doppler sonography. AJR Am J Roentgenol. 1994;163:385–9.

Hau M, Schultz H, Tony HP, Keberle M, Jahns R, Haerten R, et al. Evaluation of pannus and vascularization of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis by high-resolution ultrasound (multidimensional linear array). Arthritis Rheum. 1999;42:2303–8.PubMedCrossRef

10.

Qvistgaard E, Røgind H, Torp-Pedersen S, Terslev L, Danneskiold-Samsøe B, Bliddal H. Quantitative ultrasonography in rheumatoid arthritis: Evaluation of inflammation by Doppler technique. Ann Rheum Dis. 2001;60:690–3.

11.

Stone M, Bergin D, Whelan B, Maher M, Murray J, McCarthy C. Power Doppler ultrasound assessment of rheumatoid hand synovitis. J Rheumatol. 2001;28:1979–82.PubMed

12.

Terslev L, Torp-Pedersen S, Qvistgaard E, Bliddal H. Spectral Doppler and resistive index: A promising tool in ultrasonographic evaluation of inflammation in rheumatoid arthritis. Acta Radiol. 2003;44:645–52.

13.

Terslev L, von der Recke P, Torp-Pedersen S, Koenig MJ, Bliddal H. Diagnostic sensitivity and specificity of Doppler ultrasound in rheumatoid arthritis. J Rheumatol. 2008;35:49–53.PubMed

14.

Backhaus M, Burmester GR, Gerber T, Grassi W, Machold KP, Swen WA, et al; Working Group for Musculoskeletal Ultrasound in the EULAR Standing Committee on International Clinical Studies including Therapeutic Trials. Guidelines for musculoskeletal ultrasound in rheumatology. Ann Rheum Dis. 2001;60:641–9.PubMedCrossRef

15.

Kallio P, Ryöppy S, Jäppinen S, Siponmaa AK, Jääskeläinen J, Kunnamo I. Ultrasonography in hip disease in children. Acta Orthop Scand. 1985;56:367–71.PubMedCrossRef

16.

Miralles M, Gonzalez G, Pulpeiro JR, Millán JM, Gordillo I, Serrano C, et al. Sonography of the painful hip in children: 500 consecutive cases. AJR Am J Roentgenol. 1989;152:579–82.

17.

Marchal GJ, Van Holsbeeck MT, Raes M, Favril AA, Verbeken EE, Casteels-Vandaele M, et al. Transient synovitis of the hip in children: Role of US. Radiology. 1987;162:825–8.PubMed

18.

Rydholm U, Wingstrand H, Egund N, Elborg R, Forsberg L, Lidgren L. Sonography, arthroscopy, and intracapsular pressure in juvenile chronic arthritis of the hip. Acta Orthop Scand. 1986;57:295–8.PubMedCrossRef

19.

Haslam KE, McCann LJ, Wyatt S, Wakefield RJ. The detection of subclinical synovitis by ultrasound in oligoarticular juvenile idiopathic arthritis: A pilot study. Rheumatology (Oxford). 2010;49:123–7.

20.

Strouse PJ, DiPietro MA, Adler RS. Pediatric hip effusions: Evaluation with power Doppler sonography. Radiology. 1998;206:731–5.

21.

Terslev L, Trop-pederson S, Qvistgaard E, Danneskiold-Samsoe B, Bliddal H. Estimation of inflammation by Doppler ultrasound: Quantitative change after intra-articular treatment in rheumatoid arthritis. Ann Rheum Dis. 2003;62:1049–53.

22.

Terslev L, Torp-Pedersen S, Qvistgaard E, Kristoffersen H, Røgind H, Danneskiold-Samsøe B, et al. Effect of treatment with Etanercept (Enbrel, TNRF:Fc) on rheumatoid arthritis evaluated by Doppler ultrasonography. Ann Rheum Dis. 2003;62:178–81.PubMedCrossRef

23.

Magni-Manzoni S, Epis O, Ravelli A, Klersy C, Veisconti C, Lanni S, et al. Comparison of clinical versus ultrasound-determined synovitis in juvenile idiopathic arthritis. Arthritis Rheum. 2009;61:1497–504.PubMedCrossRef

24.

Shanmugavel C, Sodhi KS, Sandhu MS, Sidhu R, Singh S, Katariya S, et al. Role of power Doppler sonography in evaluation of therapeutic response of the knee in juvenile rheumatoid arthritis. Rheumatol Int. 2008;28:573–8.PubMedCrossRef

25.

Spârchez M, Fodor D, Miu N. The role of power Doppler ultrasonography in comparison with biological markers in the evaluation of disease activity in juvenile idiopathic arthritis. Med Ultrason. 2010;12:97–103.PubMed

26.

Laurell L, Court-Payen M, Nielsen S, Zak M, Thomsen C, Miguel-Pérez M, et al. Ultrasonography and color Doppler of proximal gluteal enthesitis in juvenile idiopathic arthritis: A descriptive study. Pediatr Rheumatol Online J. 2011;9:22. doi:10.1186/1546-0096-9-22.

Titel: Evaluation of Synovial Inflammation in Juvenile Idiopathic Arthritis by Power Color Doppler and Spectral Doppler Ultrasonography
verfasst von: Sanjeev Ranjan
Afsana Jahan
Tribhuvan Pal Yadav
Namrita Sachdev
Vivek Dewan
Shweta Singh
Publikationsdatum: 01.01.2014
Verlag: Springer India
Erschienen in: Indian Journal of Pediatrics / Ausgabe 1/2014
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-013-1085-9

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Evaluation of Synovial Inflammation in Juvenile Idiopathic Arthritis by Power Color Doppler and Spectral Doppler Ultrasonography

Abstract

Objectives

Methods

Results

Conclusions

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Abstract

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Methods

Results

Conclusions

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