12.02.2016 | Special Feature
The Japanese Breast Cancer Society clinical practice guidelines for epidemiology and prevention of breast cancer, 2015 edition
Erschienen in: Breast Cancer | Ausgabe 3/2016
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In the 2015 edition of Clinical Practice Guideline of Breast Cancer, evidence grades were used as indexes for definite causal relationships, in accordance with the 2013 edition, but recommendation grades were used for clinical questions (CQs) on prevention and risk assessment. The major revisions to the 2015 edition were as follows.-
In the section entitled “Risk factors for breast cancer” in the 2013 edition, a decrease in breast cancer risk due to obesity in premenopausal women was determined to be probable. However, a large-scale pooled analysis in Japanese women reported in 2014 showed a significant increase in breast cancer risk in premenopausal women with a high body mass index. Due to this report, the description has been changed to “obesity may increase the risk of breast cancer in premenopausal women” in the 2015 edition. Body mass in Asian women might have opposite effects on breast cancer compared to that in Western women.
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In the section entitled “Risk assessment and chemoprevention”, 2 CQs have been added on risk assessment using information on single-nucleotide polymorphisms, and on breast density and the risk of breast cancer.