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Erschienen in: Journal of Nuclear Cardiology 6/2016

01.12.2016 | Original Article

Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera

verfasst von: Jorge Daniel Oldan, MD, Linda K. Shaw, MS, Paul Hofmann, BS, Matthew Phelan, MS, Jeffrey Nelson, MHP, Robert Pagnanelli, BS, Salvador Borges-Neto, MD

Erschienen in: Journal of Nuclear Cardiology | Ausgabe 6/2016

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Abstract

Background

New multipinhole cadmium-zinc-telluride (CZT) cameras allow for faster imaging and lower radiation doses for single photon emission computed tomography (SPECT) studies, but assessment of prognostic ability is necessary.

Methods and Results

We collected data from all myocardial SPECT perfusion studies performed over 15 months at our institution, using either a CZT or conventional Anger camera. A Cox proportional hazards model was used to assess the relationship between camera type, imaging results, and either death or myocardial infarction (MI). Clinical variables including age, sex, body mass index (BMI), and historical risk factors were used for population description and model adjustments. We had 2,088 patients with a total of 69 deaths and 65 MIs (122 events altogether). A 3% increase in DDB (difference defect burden) represented a 12% increase in the risk of death or MI, whereas a 3% increase in rest defect burden or stress defect burden represented an 8% increase; these risks were the same for both cameras (P > .24, interaction tests).

Conclusions

The CZT camera has similar prognostic values for death and MI to conventional Anger cameras. This suggests that it may successfully be used to decrease patient dose.
Literatur
1.
Zurück zum Zitat Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary artery disease. N Engl J Med 1979;300:1350-8.CrossRefPubMed Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary artery disease. N Engl J Med 1979;300:1350-8.CrossRefPubMed
2.
Zurück zum Zitat Mark DB, Shaw LK, Harrell FE Jr, Hlatky MA, Lee KL, Bengtson JR, et al. Prognostic value of a treadmill exercise score in outpatients with suspected coronary artery disease. N Engl J Med 1991;325:849-53.CrossRefPubMed Mark DB, Shaw LK, Harrell FE Jr, Hlatky MA, Lee KL, Bengtson JR, et al. Prognostic value of a treadmill exercise score in outpatients with suspected coronary artery disease. N Engl J Med 1991;325:849-53.CrossRefPubMed
3.
Zurück zum Zitat Hachamovitch R, Berman DS, Kiat H, Cohen I, Cabico JA, Friedman J, et al. Exercise myocardial perfusion SPECT in patients without known coronary artery disease: Incremental prognostic value and impact on subsequent patient management. Circulation 1996;93:905-14.CrossRefPubMed Hachamovitch R, Berman DS, Kiat H, Cohen I, Cabico JA, Friedman J, et al. Exercise myocardial perfusion SPECT in patients without known coronary artery disease: Incremental prognostic value and impact on subsequent patient management. Circulation 1996;93:905-14.CrossRefPubMed
4.
Zurück zum Zitat Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: Differential stratification for risk of cardiac death and myocardial infarction. Circulation 1998;97:535-43.CrossRefPubMed Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: Differential stratification for risk of cardiac death and myocardial infarction. Circulation 1998;97:535-43.CrossRefPubMed
5.
Zurück zum Zitat Pryor DB, Shaw L, McCants CB, Lee KL, Mark DB, Harrell FE Jr, et al. Value of the history and physical in identifying patients at increased risk for coronary artery disease. Ann Intern Med 1993;118:81-90.CrossRefPubMed Pryor DB, Shaw L, McCants CB, Lee KL, Mark DB, Harrell FE Jr, et al. Value of the history and physical in identifying patients at increased risk for coronary artery disease. Ann Intern Med 1993;118:81-90.CrossRefPubMed
6.
Zurück zum Zitat Ottenhof MJ, Wai MC, Boiten HJ, Korbee RS, Valkema R, van Domburg RT, et al. 12-Year outcome after normal myocardial perfusion SPECT in patients with known coronary artery disease. J Nucl Cardiol 2013;20:748-54.CrossRefPubMed Ottenhof MJ, Wai MC, Boiten HJ, Korbee RS, Valkema R, van Domburg RT, et al. 12-Year outcome after normal myocardial perfusion SPECT in patients with known coronary artery disease. J Nucl Cardiol 2013;20:748-54.CrossRefPubMed
7.
Zurück zum Zitat Schepis T, Benz K, Haldemann A, Kaufmann PA, Schmidhausen C, Frielingsdorf J. Prognostic value of stress-gated 99 m-technetium SPECT myocardial perfusion imaging: Risk stratification of patients with multivessel coronary artery disease and prior coronary revascularization. J Nucl Cardiol 2013;20:755-62.CrossRefPubMed Schepis T, Benz K, Haldemann A, Kaufmann PA, Schmidhausen C, Frielingsdorf J. Prognostic value of stress-gated 99 m-technetium SPECT myocardial perfusion imaging: Risk stratification of patients with multivessel coronary artery disease and prior coronary revascularization. J Nucl Cardiol 2013;20:755-62.CrossRefPubMed
8.
Zurück zum Zitat Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, et al. 2012 ACCF/AHA/ACOP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease. Circulation 2012;126:3097-137.CrossRefPubMed Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, et al. 2012 ACCF/AHA/ACOP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease. Circulation 2012;126:3097-137.CrossRefPubMed
9.
Zurück zum Zitat Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Boley BD, et al. The ‘Image Gently’ campaign: Increasing CT radiation dose awareness through a national education and awareness program. Pediatr Radiol 2008;38:265-9.CrossRefPubMed Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Boley BD, et al. The ‘Image Gently’ campaign: Increasing CT radiation dose awareness through a national education and awareness program. Pediatr Radiol 2008;38:265-9.CrossRefPubMed
10.
Zurück zum Zitat Brink JA, Amis ES Jr. Image Wisely: A campaign to increase awareness about adult radiation protection. Radiology 2010;257:601-2.CrossRefPubMed Brink JA, Amis ES Jr. Image Wisely: A campaign to increase awareness about adult radiation protection. Radiology 2010;257:601-2.CrossRefPubMed
11.
Zurück zum Zitat Jafari ME, Daus AM. Applying Image Gently and Image Wisely in nuclear medicine. Health Phys 2013;104:S31-6.CrossRefPubMed Jafari ME, Daus AM. Applying Image Gently and Image Wisely in nuclear medicine. Health Phys 2013;104:S31-6.CrossRefPubMed
12.
Zurück zum Zitat GE Healthcare. Alcyone technology: white paper 2009. Document ID NU-0173-02.09-EN-US. New York: General Electric Company. GE Healthcare. Alcyone technology: white paper 2009. Document ID NU-0173-02.09-EN-US. New York: General Electric Company.
13.
Zurück zum Zitat Oddstig J, Hedeer F, Jogi J, Carlsson M, Hindorf C, Engblom H. Reduced administered activity, reduced acquisition time, and preserved image quality for the new CZT camera. J Nucl Cardiol 2013;20:38-44.CrossRefPubMed Oddstig J, Hedeer F, Jogi J, Carlsson M, Hindorf C, Engblom H. Reduced administered activity, reduced acquisition time, and preserved image quality for the new CZT camera. J Nucl Cardiol 2013;20:38-44.CrossRefPubMed
14.
Zurück zum Zitat Duvall WL, Sweeny JM, Croft LB, Ginsberg E, Guma KA, Henzlova MJ. Reduced stress dose with rapid acquisition CZT SPECT MPI in a non-obese clinical population: Comparison to coronary angiography. J Nucl Cardiol 2012;19:19-27.CrossRefPubMed Duvall WL, Sweeny JM, Croft LB, Ginsberg E, Guma KA, Henzlova MJ. Reduced stress dose with rapid acquisition CZT SPECT MPI in a non-obese clinical population: Comparison to coronary angiography. J Nucl Cardiol 2012;19:19-27.CrossRefPubMed
15.
Zurück zum Zitat Mouden M, Timmer JR, Ottervanger JP, Reiffers S, Oostdijk AH, Knollema S, et al. Impact of a new ultrafast CZT SPECT camera for myocardial perfusion imaging: Fewer equivocal results and lower radiation dose. Eur J Nucl Med Mol Imaging 2012;39:1048-55.CrossRefPubMed Mouden M, Timmer JR, Ottervanger JP, Reiffers S, Oostdijk AH, Knollema S, et al. Impact of a new ultrafast CZT SPECT camera for myocardial perfusion imaging: Fewer equivocal results and lower radiation dose. Eur J Nucl Med Mol Imaging 2012;39:1048-55.CrossRefPubMed
16.
Zurück zum Zitat Verger A, Djaballah W, Fourquet N, Rouzet F, Koehl G, Imbert L, et al. Comparison between stress myocardial perfusion SPECT recorded with cadmium-zinc-telluride and Anger cameras in various study protocols. Eur J Nucl Med Mol Imaging 2013;40:331-40.CrossRefPubMed Verger A, Djaballah W, Fourquet N, Rouzet F, Koehl G, Imbert L, et al. Comparison between stress myocardial perfusion SPECT recorded with cadmium-zinc-telluride and Anger cameras in various study protocols. Eur J Nucl Med Mol Imaging 2013;40:331-40.CrossRefPubMed
17.
Zurück zum Zitat Tanaka H, Chikamori T, Hida S, Uchida K, Igarashi Y, Yokoyama T, et al. Comparison of myocardial perfusion imaging between the new high-speed gamma camera and the standard anger camera. Circ J 2013;77:1009-17.CrossRefPubMed Tanaka H, Chikamori T, Hida S, Uchida K, Igarashi Y, Yokoyama T, et al. Comparison of myocardial perfusion imaging between the new high-speed gamma camera and the standard anger camera. Circ J 2013;77:1009-17.CrossRefPubMed
18.
Zurück zum Zitat Duvall WL, Slomka PJ, Gerlach JR, Sweeny JM, Baber U, Croft LB, et al. High-efficiency SPECT MPI: Comparison of automated quantification, visual interpretation, and coronary angiography. J Nucl Cardiol 2013;20:763-73.CrossRefPubMed Duvall WL, Slomka PJ, Gerlach JR, Sweeny JM, Baber U, Croft LB, et al. High-efficiency SPECT MPI: Comparison of automated quantification, visual interpretation, and coronary angiography. J Nucl Cardiol 2013;20:763-73.CrossRefPubMed
19.
Zurück zum Zitat Nakazato R, Berman DS, Gransar H, Hyun M, Miranda-Peats R, Kite FC, et al. Prognostic value of quantitative high-speed myocardial perfusion imaging. J Nucl Cardiol 2012;19:1113-23.CrossRefPubMedPubMedCentral Nakazato R, Berman DS, Gransar H, Hyun M, Miranda-Peats R, Kite FC, et al. Prognostic value of quantitative high-speed myocardial perfusion imaging. J Nucl Cardiol 2012;19:1113-23.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Salerno M, Elliot L, Shaw LK, Piccini JP, Pagnanelli R, Borges-Neto S. Prognostic validation of an algorithm to convert myocardial perfusion SPECT imaging data from a 12-segment model to a 17-segment model. J Nucl Cardiol 2009;16:605-13.CrossRefPubMedPubMedCentral Salerno M, Elliot L, Shaw LK, Piccini JP, Pagnanelli R, Borges-Neto S. Prognostic validation of an algorithm to convert myocardial perfusion SPECT imaging data from a 12-segment model to a 17-segment model. J Nucl Cardiol 2009;16:605-13.CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Salustri A, Pozzoli MMA, Hermans W, Ilmer B, Cornel JH, Reijs AEM, et al. Relationship between exercise echocardiography and perfusion single-photon emission computed tomography in patients with single-vessel coronary artery disease. Am Heart J 1992;124:75-83.CrossRefPubMed Salustri A, Pozzoli MMA, Hermans W, Ilmer B, Cornel JH, Reijs AEM, et al. Relationship between exercise echocardiography and perfusion single-photon emission computed tomography in patients with single-vessel coronary artery disease. Am Heart J 1992;124:75-83.CrossRefPubMed
22.
Zurück zum Zitat Harris PJ, Harrel FE Jr, Lee KL, Behar VS, Rosati RA. Survival in medically treated patients with coronary artery disease. Circulation 1979;60:1259-69.CrossRefPubMed Harris PJ, Harrel FE Jr, Lee KL, Behar VS, Rosati RA. Survival in medically treated patients with coronary artery disease. Circulation 1979;60:1259-69.CrossRefPubMed
23.
Zurück zum Zitat Rosati RA, McNeer JF, Starmer CF, Mittler BS, Morris JJ Jr, Wallace AG. A new information system for medical practice. Arch Intern Med 1975;135:1017-24.CrossRefPubMed Rosati RA, McNeer JF, Starmer CF, Mittler BS, Morris JJ Jr, Wallace AG. A new information system for medical practice. Arch Intern Med 1975;135:1017-24.CrossRefPubMed
24.
Zurück zum Zitat Stone CJ, Koo CY. Additive splines in statistics. Proc Stat Comp Sect Am Statist Assoc 1985;27:45-8. Stone CJ, Koo CY. Additive splines in statistics. Proc Stat Comp Sect Am Statist Assoc 1985;27:45-8.
25.
Zurück zum Zitat Visscher TL, Seidell JC, Molarius A, van der Kuip D, Hofman A, Witteman JC. A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: The Rotterdam study. Int J Obesity Relat Metab Disord 2001;25:1730-5.CrossRef Visscher TL, Seidell JC, Molarius A, van der Kuip D, Hofman A, Witteman JC. A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: The Rotterdam study. Int J Obesity Relat Metab Disord 2001;25:1730-5.CrossRef
26.
Zurück zum Zitat Allison DB, Zannolli R, Faith MS, Heo M, Pietrobelli A, Vanltallie TB, et al. Weight loss increases and fat loss decreases all-cause mortality rate: Results from two independent cohort studies. Int J Obesity Relat Metab Disord 1999;23:603-11.CrossRef Allison DB, Zannolli R, Faith MS, Heo M, Pietrobelli A, Vanltallie TB, et al. Weight loss increases and fat loss decreases all-cause mortality rate: Results from two independent cohort studies. Int J Obesity Relat Metab Disord 1999;23:603-11.CrossRef
Metadaten
Titel
Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera
verfasst von
Jorge Daniel Oldan, MD
Linda K. Shaw, MS
Paul Hofmann, BS
Matthew Phelan, MS
Jeffrey Nelson, MHP
Robert Pagnanelli, BS
Salvador Borges-Neto, MD
Publikationsdatum
01.12.2016
Verlag
Springer US
Erschienen in
Journal of Nuclear Cardiology / Ausgabe 6/2016
Print ISSN: 1071-3581
Elektronische ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-015-0181-9

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