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Current Obesity Reports
Erschienen in: Current Obesity Reports 1/2016

01.03.2016 | Psychological Issues (M Hetherington and V Drapeau, Section Editors)

The Second Brain: Is the Gut Microbiota a Link Between Obesity and Central Nervous System Disorders?

verfasst von: Javier Ochoa-Repáraz, Lloyd H. Kasper

Erschienen in: Current Obesity Reports | Ausgabe 1/2016

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Abstract

The gut-brain axis is a bi-directional integrated system composed by immune, endocrine, and neuronal components by which the gap between the gut microbiota and the brain is significantly impacted. An increasing number of different gut microbial species are now postulated to regulate brain function in health and disease. The westernized diet is hypothesized to be the cause of the current obesity levels in many countries, a major socio-economical health problem. Experimental and epidemiological evidence suggest that the gut microbiota is responsible for significant immunologic, neuronal, and endocrine changes that lead to obesity. We hypothesize that the gut microbiota, and changes associated with diet, affect the gut-brain axis and may possibly contribute to the development of mental illness. In this review, we discuss the links between diet, gut dysbiosis, obesity, and immunologic and neurologic diseases that impact brain function and behavior.
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Metadaten
Titel
The Second Brain: Is the Gut Microbiota a Link Between Obesity and Central Nervous System Disorders?
verfasst von
Javier Ochoa-Repáraz
Lloyd H. Kasper
Publikationsdatum
01.03.2016
Verlag
Springer US
Erschienen in
Current Obesity Reports / Ausgabe 1/2016
Elektronische ISSN: 2162-4968
DOI
https://doi.org/10.1007/s13679-016-0191-1

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„Jeder Fall von plötzlichem Tod muss obduziert werden!“

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Ein signifikanter Anteil der Fälle von plötzlichem Herztod ist genetisch bedingt. Um ihre Verwandten vor diesem Schicksal zu bewahren, sollten jüngere Personen, die plötzlich unerwartet versterben, ausnahmslos einer Autopsie unterzogen werden.

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

17.05.2024 Vorhofflimmern Nachrichten

Nicht nur ein vergrößerter, sondern auch ein kleiner linker Ventrikel ist bei Vorhofflimmern mit einer erhöhten Komplikationsrate assoziiert. Der Zusammenhang besteht nach Daten aus China unabhängig von anderen Risikofaktoren.

Update Innere Medizin

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