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Molecular Diagnosis & Therapy
Erschienen in: Molecular Diagnosis & Therapy 5/2016

01.10.2016 | Review Article

Liquid Biopsies in Oncology and the Current Regulatory Landscape

verfasst von: Lindsay N. Strotman, Lori M. Millner, Roland Valdes Jr., Mark W. Linder

Erschienen in: Molecular Diagnosis & Therapy | Ausgabe 5/2016

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Abstract

There is a profound need in oncology to detect cancer earlier, guide individualized therapies, and better monitor progress during treatment. Currently, some of this information can be achieved through solid tissue biopsy and imaging. However, these techniques are limited because of the invasiveness of the procedure and the size of the tumor. A liquid biopsy can overcome these barriers as its non-invasive nature allows samples to be collected over time. Liquid biopsies may also allow earlier detection than traditional imaging. Liquid biopsies include the analysis of circulating tumor cells (CTCs), cell-free nucleic acid (cfNA), or extracellular vesicles obtained from a variety of biofluids, such as peripheral blood. In this review, we discuss different liquid biopsy types and how they fit into the current regulatory landscape.
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Metadaten
Titel
Liquid Biopsies in Oncology and the Current Regulatory Landscape
verfasst von
Lindsay N. Strotman
Lori M. Millner
Roland Valdes Jr.
Mark W. Linder
Publikationsdatum
01.10.2016
Verlag
Springer International Publishing
Erschienen in
Molecular Diagnosis & Therapy / Ausgabe 5/2016
Print ISSN: 1177-1062
Elektronische ISSN: 1179-2000
DOI
https://doi.org/10.1007/s40291-016-0220-5

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