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Erschienen in: High Blood Pressure & Cardiovascular Prevention 4/2015

01.12.2015 | Review Article

Structural and Functional Abnormalities of Carotid Artery and Their Relation with EVA Phenomenon

verfasst von: Alessandro Maloberti, Paolo Meani, Marisa Varrenti, Luca Giupponi, Miriam Stucchi, Paola Vallerio, Cristina Giannattasio

Erschienen in: High Blood Pressure & Cardiovascular Prevention | Ausgabe 4/2015

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Abstract

Early vascular aging is a process characterized by a reduction in arterial elastin with an increase in collagen that has been related to cardiovascular risk factor and can determine an increased arterial stiffness and central blood pressure. It can be measured by several non invasive methods and in different arterial segment. The present paper will focus on functional (local stiffness parameter) and structural (intima media thickness) carotid arteries alterations typically evaluated by ultrasound methods. Methodological, research and clinical issue has been reviewed.
Literatur
1.
Zurück zum Zitat Nilsson PM, Lurbe E, Laurent S. The early origins of vascular ageing and cardiovascular risk: the EVA syndrome. J Hypertens. 2008;26:1049–57.CrossRefPubMed Nilsson PM, Lurbe E, Laurent S. The early origins of vascular ageing and cardiovascular risk: the EVA syndrome. J Hypertens. 2008;26:1049–57.CrossRefPubMed
2.
Zurück zum Zitat Nilsson PM, Boutouyrie P, Cunha P, Kotsis V, Narkiewicz K, Parati G, Rietzschel E, Scuteri A, Laurent S. Early vascular ageing in translation: from laboratory investigations to clinical applications in cardiovascular prevention. J Hypertens. 2013;31(8):1517–26.CrossRefPubMed Nilsson PM, Boutouyrie P, Cunha P, Kotsis V, Narkiewicz K, Parati G, Rietzschel E, Scuteri A, Laurent S. Early vascular ageing in translation: from laboratory investigations to clinical applications in cardiovascular prevention. J Hypertens. 2013;31(8):1517–26.CrossRefPubMed
3.
Zurück zum Zitat Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson I, Struijker-Boudier H, European Network for Non-invasive Investigation of Large Arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006;27(21):2588–605.CrossRefPubMed Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson I, Struijker-Boudier H, European Network for Non-invasive Investigation of Large Arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006;27(21):2588–605.CrossRefPubMed
4.
Zurück zum Zitat Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation. 1997;96:1432–7.CrossRefPubMed Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation. 1997;96:1432–7.CrossRefPubMed
5.
Zurück zum Zitat O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999;340(14–22):5. O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999;340(14–22):5.
6.
Zurück zum Zitat Nambi V, Chambless L, Folsom AR, He M, Hu Y, Mosley T, et al. Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study. J Am Coll Cardiol. 2010;55:1600–7.PubMedCentralCrossRefPubMed Nambi V, Chambless L, Folsom AR, He M, Hu Y, Mosley T, et al. Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study. J Am Coll Cardiol. 2010;55:1600–7.PubMedCentralCrossRefPubMed
7.
Zurück zum Zitat Zanchetti A, Bond MG, Hennig M, Neiss A, Mancia G, Dal Palu C, et al. Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis: principal results of the European Lacidipine Study on Atherosclerosis (ELSA), a randomized, double-blind, long-term trial. Circulation. 2002;106:2422–7.CrossRefPubMed Zanchetti A, Bond MG, Hennig M, Neiss A, Mancia G, Dal Palu C, et al. Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis: principal results of the European Lacidipine Study on Atherosclerosis (ELSA), a randomized, double-blind, long-term trial. Circulation. 2002;106:2422–7.CrossRefPubMed
8.
Zurück zum Zitat Lorenz MW, von Kegler S, Steinmetz H, Markus HS, Sitzer M. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 2006;37(1):87–92.CrossRefPubMed Lorenz MW, von Kegler S, Steinmetz H, Markus HS, Sitzer M. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 2006;37(1):87–92.CrossRefPubMed
9.
Zurück zum Zitat Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation. 2007;115(4):459–67.CrossRefPubMed Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation. 2007;115(4):459–67.CrossRefPubMed
10.
Zurück zum Zitat Giannattasio C, Failla M, Piperno A, Grappiolo A, Gamba P, Paleari F, Mancia G. Early impairment of large artery structure and function in type I diabetes mellitus. Diabetologia. 1999;42(8):987–94.CrossRefPubMed Giannattasio C, Failla M, Piperno A, Grappiolo A, Gamba P, Paleari F, Mancia G. Early impairment of large artery structure and function in type I diabetes mellitus. Diabetologia. 1999;42(8):987–94.CrossRefPubMed
11.
Zurück zum Zitat Giannattasio C, Failla M, Grappiolo A, Gamba PL, Paleari F, Mancia G. Progression of large artery structural and functional alterations in Type I diabetes. Diabetologia. 2001;44(2):203–8.CrossRefPubMed Giannattasio C, Failla M, Grappiolo A, Gamba PL, Paleari F, Mancia G. Progression of large artery structural and functional alterations in Type I diabetes. Diabetologia. 2001;44(2):203–8.CrossRefPubMed
12.
Zurück zum Zitat Moon JH, Lim S, Han JW, Kim KM, Choi SH, Park KS, Kim KW, Jang HC. Carotid intima-media thickness is associated with the progression of cognitive impairment in older adults. Stroke. 2015;46(4):1024–30.CrossRefPubMed Moon JH, Lim S, Han JW, Kim KM, Choi SH, Park KS, Kim KW, Jang HC. Carotid intima-media thickness is associated with the progression of cognitive impairment in older adults. Stroke. 2015;46(4):1024–30.CrossRefPubMed
13.
Zurück zum Zitat Sander K, Bickel H, Förstl H, Etgen T, Briesenick C, Poppert H, Sander D. Carotid- intima media thickness is independently associated with cognitive decline. The INVADE study. Int J Geriatr Psychiatry. 2010;25(4):389–94.CrossRefPubMed Sander K, Bickel H, Förstl H, Etgen T, Briesenick C, Poppert H, Sander D. Carotid- intima media thickness is independently associated with cognitive decline. The INVADE study. Int J Geriatr Psychiatry. 2010;25(4):389–94.CrossRefPubMed
14.
Zurück zum Zitat Rosvall M, Persson M, Östling G, Nilsson PM, Melander O, Hedblad B, Engström G. Risk factors for the progression of carotid intima-media thickness over a 16-year follow-up period: the Malmö Diet and Cancer Study. Atherosclerosis. 2015;239(2):615–21.CrossRefPubMed Rosvall M, Persson M, Östling G, Nilsson PM, Melander O, Hedblad B, Engström G. Risk factors for the progression of carotid intima-media thickness over a 16-year follow-up period: the Malmö Diet and Cancer Study. Atherosclerosis. 2015;239(2):615–21.CrossRefPubMed
15.
Zurück zum Zitat Gaibazzi N, Rigo F, Facchetti R, Carerj S, Giannattasio C, Moreo A, Mureddu G, Paini A, Grolla E, Faden G, Cesana F, Faggiano P. Ultrasound carotid intima-media thickness, carotid plaque and cardiac calcium incrementally add to the Framingham Risk Score for the prediction of angiographic coronary artery disease: a multicenter prospective study. Int J Cardiol. 2014;177(2):708–10.CrossRefPubMed Gaibazzi N, Rigo F, Facchetti R, Carerj S, Giannattasio C, Moreo A, Mureddu G, Paini A, Grolla E, Faden G, Cesana F, Faggiano P. Ultrasound carotid intima-media thickness, carotid plaque and cardiac calcium incrementally add to the Framingham Risk Score for the prediction of angiographic coronary artery disease: a multicenter prospective study. Int J Cardiol. 2014;177(2):708–10.CrossRefPubMed
16.
Zurück zum Zitat Yoshida M, Mita T, Yamamoto R, Shimizu T, Ikeda F, Ohmura C, Kanazawa A, Hirose T, Kawamori R, Watada H. Combination of the Framingham risk score and carotid intima-media thickness improves the prediction of cardiovascular events in patients with type 2 diabetes. Diabetes Care. 2012;35(1):178–80.PubMedCentralCrossRefPubMed Yoshida M, Mita T, Yamamoto R, Shimizu T, Ikeda F, Ohmura C, Kanazawa A, Hirose T, Kawamori R, Watada H. Combination of the Framingham risk score and carotid intima-media thickness improves the prediction of cardiovascular events in patients with type 2 diabetes. Diabetes Care. 2012;35(1):178–80.PubMedCentralCrossRefPubMed
17.
Zurück zum Zitat Ataoglu HE, Saler T, Uzunhasan I, Yenigun M, Yigit Z, Temiz LU, Saglam Z, Cetin F, Kumbasar B, Sar F. Additional value of carotid artery intima-media thickness in cardiovascular risk assessment by Framingham risk-score in Type 2 diabetes: a retrospective cohort study. J Diabetes. 2009;1(3):188–93.CrossRefPubMed Ataoglu HE, Saler T, Uzunhasan I, Yenigun M, Yigit Z, Temiz LU, Saglam Z, Cetin F, Kumbasar B, Sar F. Additional value of carotid artery intima-media thickness in cardiovascular risk assessment by Framingham risk-score in Type 2 diabetes: a retrospective cohort study. J Diabetes. 2009;1(3):188–93.CrossRefPubMed
18.
Zurück zum Zitat Fujihara K, Suzuki H, Sato A, Ishizu T, Kodama S, Heianza Y, Saito K, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Sone H, Shimano H. Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery stenosis in patients with asymptomatic type 2 diabetes. J Atheroscler Thromb. 2014;21(8):799–815.CrossRefPubMed Fujihara K, Suzuki H, Sato A, Ishizu T, Kodama S, Heianza Y, Saito K, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Sone H, Shimano H. Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery stenosis in patients with asymptomatic type 2 diabetes. J Atheroscler Thromb. 2014;21(8):799–815.CrossRefPubMed
19.
Zurück zum Zitat Baldassarre D, Hamsten A, Veglia F, de Faire U, Humphries SE, Smit AJ, Giral P, Kurl S, Rauramaa R, Mannarino E, Grossi E, Paoletti R, Tremoli E, IMPROVE Study Group. Measurements of carotid intima-media thickness and of interadventitia common carotid diameter improve prediction of cardiovascular events: results of the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predictors of Vascular Events in a High Risk European Population) study. J Am Coll Cardiol. 2012;60(16):1489–99.CrossRefPubMed Baldassarre D, Hamsten A, Veglia F, de Faire U, Humphries SE, Smit AJ, Giral P, Kurl S, Rauramaa R, Mannarino E, Grossi E, Paoletti R, Tremoli E, IMPROVE Study Group. Measurements of carotid intima-media thickness and of interadventitia common carotid diameter improve prediction of cardiovascular events: results of the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predictors of Vascular Events in a High Risk European Population) study. J Am Coll Cardiol. 2012;60(16):1489–99.CrossRefPubMed
20.
Zurück zum Zitat Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986;74(6):1399–406.CrossRefPubMed Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986;74(6):1399–406.CrossRefPubMed
21.
Zurück zum Zitat Engelen L, Ferreira I, Stehouwer CD, Boutouyrie P, Laurent S, Reference Values for Arterial Measurements Collaboration. Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors. Eur Heart J. 2013;34(30):2368–80.CrossRefPubMed Engelen L, Ferreira I, Stehouwer CD, Boutouyrie P, Laurent S, Reference Values for Arterial Measurements Collaboration. Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors. Eur Heart J. 2013;34(30):2368–80.CrossRefPubMed
22.
Zurück zum Zitat Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Desvarieux M, Ebrahim S, Fatar M, Hernandez Hernandez R, Kownator S, Prati P, Rundek T, Taylor A, Bornstein N, Csiba L, Vicaut E, Woo KS, Zannad F, Advisory Board of the 3rd Watching the Risk Symposium 2004, 13th European Stroke Conference. Mannheim intima-media thickness consensus. Cerebrovasc Dis. 2004;18(4):346–9.CrossRefPubMed Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Desvarieux M, Ebrahim S, Fatar M, Hernandez Hernandez R, Kownator S, Prati P, Rundek T, Taylor A, Bornstein N, Csiba L, Vicaut E, Woo KS, Zannad F, Advisory Board of the 3rd Watching the Risk Symposium 2004, 13th European Stroke Conference. Mannheim intima-media thickness consensus. Cerebrovasc Dis. 2004;18(4):346–9.CrossRefPubMed
23.
Zurück zum Zitat Freire CM, Ribeiro AL, Barbosa FB, Nogueira AI, de Almeida MC, Barbosa MM, Lana AM, e Silva AC, Ribeiro-Oliveira A. Comparison between automated and manual measurements of carotid intima-media thickness in clinical practice. Vasc Health Risk Manag. 2009;5:811–7.PubMedCentralPubMed Freire CM, Ribeiro AL, Barbosa FB, Nogueira AI, de Almeida MC, Barbosa MM, Lana AM, e Silva AC, Ribeiro-Oliveira A. Comparison between automated and manual measurements of carotid intima-media thickness in clinical practice. Vasc Health Risk Manag. 2009;5:811–7.PubMedCentralPubMed
24.
Zurück zum Zitat Wong M, Edelstein J, Wollman J, Bond MG. Ultrasonic-pathological comparison of the human arterial wall. Verification of intima-media thickness. Arterioscler Thromb. 1993;13(4):482–6.CrossRefPubMed Wong M, Edelstein J, Wollman J, Bond MG. Ultrasonic-pathological comparison of the human arterial wall. Verification of intima-media thickness. Arterioscler Thromb. 1993;13(4):482–6.CrossRefPubMed
25.
Zurück zum Zitat Touboul PJ, Prati P, Scarabin PY, Adrai V, Thibout E, Ducimetiere P. Use of monitoring software to improve the measurement of carotid wall thickness by B-mode imaging. J Hypertens Suppl. 1992;10(5):S37–41.PubMed Touboul PJ, Prati P, Scarabin PY, Adrai V, Thibout E, Ducimetiere P. Use of monitoring software to improve the measurement of carotid wall thickness by B-mode imaging. J Hypertens Suppl. 1992;10(5):S37–41.PubMed
26.
Zurück zum Zitat Palombo C, Kozakova M, Guraschi N, Bini G, Cesana F, Castoldi G, Stella A, Morizzo C, Giannattasio C. Radiofrequency-based carotid wall tracking: a comparison between two different systems. J Hypertens. 2012;30(8):1614–9.CrossRefPubMed Palombo C, Kozakova M, Guraschi N, Bini G, Cesana F, Castoldi G, Stella A, Morizzo C, Giannattasio C. Radiofrequency-based carotid wall tracking: a comparison between two different systems. J Hypertens. 2012;30(8):1614–9.CrossRefPubMed
27.
Zurück zum Zitat Blacher J, Pannier B, Guerin AP, Marchais SJ, Safar ME, London GM. Carotid arterial stiffness as a predictor of cardiovascular and all-cause mortality in end-stage renal disease. Hypertension. 1998;32(3):570–4.CrossRefPubMed Blacher J, Pannier B, Guerin AP, Marchais SJ, Safar ME, London GM. Carotid arterial stiffness as a predictor of cardiovascular and all-cause mortality in end-stage renal disease. Hypertension. 1998;32(3):570–4.CrossRefPubMed
28.
Zurück zum Zitat Barenbrock M, Kosch M, Jöster E, Kisters K, Rahn KH, Hausberg M. Reduced arterial distensibility is a predictor of cardiovascular disease in patients after renal transplantation. J Hypertens. 2002;20(1):79–84.CrossRefPubMed Barenbrock M, Kosch M, Jöster E, Kisters K, Rahn KH, Hausberg M. Reduced arterial distensibility is a predictor of cardiovascular disease in patients after renal transplantation. J Hypertens. 2002;20(1):79–84.CrossRefPubMed
29.
Zurück zum Zitat Giannattasio C, Capra A, Facchetti R, Viscardi L, Bianchi F, Failla M, Colombo V, Grieco A, Mancia G. Relationship between arterial distensibility and coronary atherosclerosis in angina patients. J Hypertens. 2007;25:593–8.CrossRefPubMed Giannattasio C, Capra A, Facchetti R, Viscardi L, Bianchi F, Failla M, Colombo V, Grieco A, Mancia G. Relationship between arterial distensibility and coronary atherosclerosis in angina patients. J Hypertens. 2007;25:593–8.CrossRefPubMed
30.
Zurück zum Zitat Failla M, Grappiolo A, Carugo S, Calchera I, Giannattasio C, Mancia G. Effects of cigarette smoking on carotid and radial artery distensibility. J Hypertens. 1997;15:1659–64.CrossRefPubMed Failla M, Grappiolo A, Carugo S, Calchera I, Giannattasio C, Mancia G. Effects of cigarette smoking on carotid and radial artery distensibility. J Hypertens. 1997;15:1659–64.CrossRefPubMed
31.
Zurück zum Zitat Giannattasio C, Failla M, Capra A, Scanziani E, Amigoni M, Boffi L, Whistock C, Gamba P, Paleari F, Mancia G. Increased arterial stiffness in normoglycemic normotensive offspring of type 2 diabetic parents. Hypertension. 2008;51(2):182–7.CrossRefPubMed Giannattasio C, Failla M, Capra A, Scanziani E, Amigoni M, Boffi L, Whistock C, Gamba P, Paleari F, Mancia G. Increased arterial stiffness in normoglycemic normotensive offspring of type 2 diabetic parents. Hypertension. 2008;51(2):182–7.CrossRefPubMed
32.
Zurück zum Zitat Giannattasio C, Achilli F, Failla M, Capra A, Vincenzi A, Valagussa F, Mancia G. Radial, carotid and aortic distensibility in congestive heart failure: effects of high-dose angiotensin-converting enzyme inhibitor or low-dose association with angiotensin type 1 receptor blockade. J Am Coll Cardiol. 2002;39(8):1275–82.CrossRefPubMed Giannattasio C, Achilli F, Failla M, Capra A, Vincenzi A, Valagussa F, Mancia G. Radial, carotid and aortic distensibility in congestive heart failure: effects of high-dose angiotensin-converting enzyme inhibitor or low-dose association with angiotensin type 1 receptor blockade. J Am Coll Cardiol. 2002;39(8):1275–82.CrossRefPubMed
33.
Zurück zum Zitat Giannattasio C, Achilli F, Grappiolo A, Failla M, Meles E, Gentile G, Calchera I, Capra A, Baglivo J, Vincenzi A, Sala L, Mancia G. Radial artery flow-mediated dilatation in heart failure patients: effects of pharmacological and nonpharmacological treatment. Hypertension. 2001;38(6):1451–5.CrossRefPubMed Giannattasio C, Achilli F, Grappiolo A, Failla M, Meles E, Gentile G, Calchera I, Capra A, Baglivo J, Vincenzi A, Sala L, Mancia G. Radial artery flow-mediated dilatation in heart failure patients: effects of pharmacological and nonpharmacological treatment. Hypertension. 2001;38(6):1451–5.CrossRefPubMed
34.
Zurück zum Zitat Kool MJF, Van Merode T, Reneman RS, Hoeks APG, StruykerBoudier H, Van Bortel LMAB. Evaluation of reproducibility of a vessel wall movement detector system for assessment of large artery properties. Cardiovasc Re. 1994;28:610–4.CrossRef Kool MJF, Van Merode T, Reneman RS, Hoeks APG, StruykerBoudier H, Van Bortel LMAB. Evaluation of reproducibility of a vessel wall movement detector system for assessment of large artery properties. Cardiovasc Re. 1994;28:610–4.CrossRef
35.
Zurück zum Zitat Bussy C, Boutouyrie P, Lacolley P, Challande P, Laurent S. Intrinsic stiffness of the carotid artery wall material in essential hypertensives. Hypertension. 2000;35:1049–54.CrossRefPubMed Bussy C, Boutouyrie P, Lacolley P, Challande P, Laurent S. Intrinsic stiffness of the carotid artery wall material in essential hypertensives. Hypertension. 2000;35:1049–54.CrossRefPubMed
36.
Zurück zum Zitat Giannarelli C, Bianchini E, Bruno RM, Magagna A, Landini L, Faita F, Gemignani V, Penno G, Taddei S, Ghiadoni L. Local carotid stiffness and intima-media thickness assessment by a novel ultrasound-based system in essential hypertension. Atherosclerosis. 2012;223(2):372–7.CrossRefPubMed Giannarelli C, Bianchini E, Bruno RM, Magagna A, Landini L, Faita F, Gemignani V, Penno G, Taddei S, Ghiadoni L. Local carotid stiffness and intima-media thickness assessment by a novel ultrasound-based system in essential hypertension. Atherosclerosis. 2012;223(2):372–7.CrossRefPubMed
37.
Zurück zum Zitat Dan HJ, Wang Y, Sha HJ, Wen SB. Quantitative evaluation of the structure and function of the common carotid artery in hypertriglyceridemic subjects using ultrasound radiofrequency-data technology. Eur J Radiol. 2012;81(11):3289–93.CrossRefPubMed Dan HJ, Wang Y, Sha HJ, Wen SB. Quantitative evaluation of the structure and function of the common carotid artery in hypertriglyceridemic subjects using ultrasound radiofrequency-data technology. Eur J Radiol. 2012;81(11):3289–93.CrossRefPubMed
38.
Zurück zum Zitat Van Sloten TT, Schram MT, Can den Hurk K, Dekker JM, Nijpels G, Henry RM, Stehouwer CD. Local stiffness of the carotid and femoral artery is associated with incident cardiovascular events and all-cause mortality: the Hoorn study. J Am Coll Cardiol. 2014;63(17):1739–47.CrossRefPubMed Van Sloten TT, Schram MT, Can den Hurk K, Dekker JM, Nijpels G, Henry RM, Stehouwer CD. Local stiffness of the carotid and femoral artery is associated with incident cardiovascular events and all-cause mortality: the Hoorn study. J Am Coll Cardiol. 2014;63(17):1739–47.CrossRefPubMed
Metadaten
Titel
Structural and Functional Abnormalities of Carotid Artery and Their Relation with EVA Phenomenon
verfasst von
Alessandro Maloberti
Paolo Meani
Marisa Varrenti
Luca Giupponi
Miriam Stucchi
Paola Vallerio
Cristina Giannattasio
Publikationsdatum
01.12.2015
Verlag
Springer International Publishing
Erschienen in
High Blood Pressure & Cardiovascular Prevention / Ausgabe 4/2015
Print ISSN: 1120-9879
Elektronische ISSN: 1179-1985
DOI
https://doi.org/10.1007/s40292-015-0100-9

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