Background
Methods
Data analysis
Results
Parameters | Mean ± SD | R2
| P-value |
---|---|---|---|
N = 3475 (Males = 756; Females = 2719) | |||
Age (years) | 46.9 ± 16.3 | 0.15 | < 0.0001 |
Weight (kg) | 75.2 ± 18.2 | −0.06 | 0.005 |
Height (cm) | 147.0 ± 18.0 | 0.01 | 0.64 |
BMI (kg/ m2) | 36.4 ± 13.8 | −0.03 | 0.17 |
Systolic blood pressure (mmHg) | 122.0 ± 19.0 | 0.05 | 0.03 |
Diastolic blood pressure (mmHg) | 71.0 ± 11.0 | 0.04 | 0.09 |
Glucose (mmol/L) | 6.4 ± 3.0 | 0.02 | 0.24 |
HbA1c (%) | 7.0 ± 1.9 | 0.01 | 0.70 |
Albumin (g/L) | 46.0 ± 4.9 | 0.11 | <0.0001 |
Alkaline phosphatase (U/L)# | 97.1 ± 82.7 | −0.09 | 0.0002 |
BUN (mmol/L) | 5.1 ± 3.4 | 0.03 | 0.12 |
Calcium (mmol/L) | 2.34 ± 0.15 | 0.14 | <0.0001 |
Creatinine (umol/L)# | 79.4 ± 70.2 | −0.01 | 0.48 |
25OH Vitamin D (nmol/L)# | 35.5 ± 30.6 | 1.00 | -- |
Phosphorus (mmol/L) | 1.14 ± 0.23 | 0.09 | 0.0007 |
PTH (mmol/L)# | 34.2 ± 58.3 | −0.10 | 0.0007 |
Parameters |
25 (OH) vitamin D cut-offs (nmol/L)
| |||||
---|---|---|---|---|---|---|
< 25 | ≥ 25 | < 50 | ≥ 50 | < 75 | ≥ 75 | |
N | 1601 | 1874 | 2672 | 803 | 3110 | 365 |
Age (years) | 43.5 ± 16.3 | 49.9 ± 15.8** | 45.7 ± 16.3 | 51.0 ± 15.8** | 46.6 ± 16.3 | 49.8 ± 15.8** |
BMI (kg/ m2) | 35.1 ± 12.6 | 37.9 ± 14.8** | 37.1 ± 14.9 | 33.8 ± 11.5** | 37.0 ± 14.0 | 30.3 ± 7.7** |
Systolic blood pressure (mmHg) | 120.0 ± 19.0 | 124.0 ± 19.0** | 122.0 ± 19.0 | 123.0 ± 17.0 | 122.0 ± 19.0 | 121.0 ± 16.0 |
Diastolic blood pressure (mmHg) | 70.0 ± 11.0 | 72.0 ± 11.0** | 71.0 ± 11.0 | 71.0 ± 11.0 | 71.0 ± 11.0 | 70.0 ± 10.0 |
Glucose (mmol/L) | 6.2 ± 2.6 | 6.5 ± 3.4** | 6.4 ± 2.9 | 6.4 ± 3.4 | 6.4 ± 3.0 | 6.6 ± 2.8 |
HbA1c (%) | 6.9 ± 1.8 | 7.1 ± 1.9 | 7.1 ± 1.9 | 6.9 ± 1.8 | 7.0 ± 1.9 | 6.8 ± 1.9 |
Albumin (g/L) | 45.6 ± 5.1 | 46.3 ± 4.5** | 45.7 ± 5.0 | 46.9 ± 3.9** | 45.9 ± 4.9 | 46.9 ± 4.0** |
Alkaline phosphatase (U/L) | 106.0 ± 103.0 | 90.0 ± 60.0** | 100.0 ± 88.0 | 88.0 ± 69.0** | 98.0 ± 85.0 | 91.0 ± 58.0 |
BUN (mmol/L) | 4.9 ± 3.5 | 5.3 ± 3.3** | 5.0 ± 3.5 | 5.2 ± 2.8 | 5.1 ± 3.5 | 5.0 ± 2.2 |
Calcium (mmol/L) | 2.3 ± 0.2 | 2.4 ± 0.2** | 2.3 ± 0.2 | 2.4 ± 0.1** | 2.33 ± 0.15 | 2.37 ± 0.15** |
Creatinine (umol/L) | 77.0 ± 65.0 | 82.0 ± 74.0 | 80.0 ± 75.0 | 77.0 ± 53.0 | 80.0 ± 74.0 | 73.0 ± 21.0 |
Phosphorus (mmol/L) | 1.11 ± 0.24 | 1.16 ± 0.22** | 1.13 ± 0.24 | 1.15 ± 0.21 | 1.13 ± 0.23 | 1.15 ± 0.22 |
PTH (pmol/L) | 38.0 ± 67.0 | 31.0 ± 51.0 | 36.0 ± 62.0 | 28.0 ± 48.0** | 36.0 ± 61.0 | 25.0 ± 35.0* |