Central serous retinopathy (CSR) is an exudative chorioretinopathy characterized by an exudative neurosensory retinal detachment with or without an associated detachment of the retinal pigment epithelium (RPE). It typically occurs in young, healthy adults and is usually idiopathic. The age range at the time of first diagnosis is generally from 22 to 83 years, and patients older than 50 years of age tend to have bilateral disease, systemic hypertension and a history of corticosteroid use [
1]. Rare variants of CSR with chronic, bilateral, extrafoveal, multifocal and bullous retinal detachments have also been observed in patients undergoing cardiac transplantation [
2]. Liver disease may be involved in sight-threatening eye diseases. The ophthalmic pathologies of cirrhosis in the literature include xerophthalmia, vitamin A deficiency and color blindness [
3]. Abe
et al. found retinopathy with hemorrhages and exudates in 31.8% of patients with hepatitis C, irrespective of liver cirrhosis [
4]. According to Onder
et al., retinopathy can be present not only in hepatitis C-positive patients but also in patients with other causes of liver cirrhosis, and soft exudates may develop in cirrhotic patients, probably due to loss of the synthetic function of the liver and the hemodynamic effects of portal hypertension [
3]. Haimovici
et al. showed a statistically significant relationship between alcohol intake and CSR [
5]. Experimental studies have shown serous retinal detachment secondary to alteration of choroidal vascular permeability [
6]. One of the studies suggests that ischemia at the level of the choroid can cause capillary and venous congestion with increased fluid transudation [
7]. We report a unique case of bilateral multifocal CSR secondary to alcoholic chronic liver disease in a 58-year-old man.