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Arthritis Research & Therapy
Erschienen in: Arthritis Research & Therapy 5/2008

01.10.2008 | Review

Genetic studies in osteoporosis – the end of the beginning

verfasst von: Emma L Duncan, Matthew A Brown

Erschienen in: Arthritis Research & Therapy | Ausgabe 5/2008

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Abstract

Osteoporosis and disorders of bone fragility are highly heritable, but despite much effort the identities of few of the genes involved has been established. Recent developments in genetics such as genome-wide association studies are revolutionizing research in this field, and it is likely that further contributions will be made through application of next-generation sequencing technologies, analysis of copy number variation polymorphisms, and high-throughput mouse mutagenesis programs. This article outlines what we know about osteoporosis genetics to date and the probable future directions of research in this field.
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Metadaten
Titel
Genetic studies in osteoporosis – the end of the beginning
verfasst von
Emma L Duncan
Matthew A Brown
Publikationsdatum
01.10.2008
Verlag
BioMed Central
Erschienen in
Arthritis Research & Therapy / Ausgabe 5/2008
Elektronische ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar2479

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