Background
Methods
Study sample
Antidepressant trend groups
Relationship between antidepressant prescription trend group and auxiliary indicators of mental illness
Relationship between antidepressant prescription trend group and individual and neighbourhood risk factors
Results
Antidepressant prescription trend groups
Relationship between antidepressant prescription trend group and auxiliary indicators of mental illness
Antidepressant Prescription Group | ||||||
---|---|---|---|---|---|---|
Variable | Reference | No prescriptions OR (95% CI) | Occasional OR (95% CI) | Decreasing OR (95% CI) | Increasing OR (95% CI) | Mostly OR (95% CI) |
Self-reported mental illness in 2011 | No self-reported mental illness in 2011 | 0.09 (0.02, 0.15) | 0.84 (0.76, 0.92) | 3.83 (3.74, 3.93) | 1.84 (1.75, 1.93) | 12.97 (12.92, 13.03) |
Hospital Admission for mental health care from 2001 to 2008 | No Hospital Psychiatric Admission 2001–2008 | 0.20 (0.03, 0.36) | 0.72 (0.48, 0.96) | 1.79 (1.52, 1.41) | 1.13 (0.86, 1.41) | 6.04 (5.89, 6.20) |
Anxiolytic Prescription | No anxiolytics prescription (2009–2014) | 0.13 (0.08, 0.19) | 1.91 (1.85, 1.97) | 2.58 (2.48, 2.67) | 3.28 (3.20, 3.35) | 4.91 (4.85, 4.96) |
Antipsychotics Prescription | No antipsychotic prescription (2009–2014) | 0.15 (0.07, 0.23) | 1.21 (1.11, 1.31) | 2.12 (1.98, 2.26) | 2.17 (2.05, 2.29) | 6.16 (6.08, 6.24) |
Relationship between antidepressant prescription trend group and individual and neighbourhood risk factors
Antidepressant Prescription Group | ||||||
---|---|---|---|---|---|---|
Variable | Reference | No prescriptions | Occasional | Decreasing | Increasing | Mostly |
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | ||
Sex (Female) | Male | 0.49 | 1.53 | 1.76 | 1.80 | 2.19 |
(0.46, 0.52) | (1.49, 1.57) | (1.69, 1.83) | (1.75, 1.86) | (2.15, 2.24) | ||
Age (36:45) | 26:35 (in 2011) | 0.92 | 0.82 | 1.08 | 0.99 | 1.86 |
(0.88, 0.97) | (0.76, 0.88) | (0.96, 1.19) | (0.90, 1.07) | (1.78, 1.95) | ||
Age (46:55) | 0.91 | 0.79 | 0.92 | 0.85 | 2.32 | |
(0.86, 0.95) | (0.73, 0.85) | (0.80, 1.04) | (0.76, 0.94) | (2.24, 2.40) | ||
Age (56:65) | 1.2 | 0.61 | 0.87 | 0.61 | 1.97 | |
(1.15, 1.25) | (0.54, 0.68) | (0.73, 1.00) | (0.50, 0.72) | (1.88, 2.06) | ||
Age (66:75) | 1.53 | 0.58 | 0.72 | 0.55 | 1.36 | |
(1.47, 1.60) | (0.49, 0.67) | (0.54, 0.90) | (0.40, 0.70) | (1.25, 1.47) | ||
Age (76:85) | 1.47 | 0.75 | 0.74 | 0.62 | 1.04 | |
(1.40, 1.55) | (0.65, 0.86) | (0.54, 0.94) | (0.45, 0.79) | (0.91, 1.16) | ||
Age (86+) | 1.57 | 0.80 | 0.94 | 0.66 | 0.67 | |
(1.47, 1.68) | (0.66, 0.95) | (0.68, 1.19) | (0.43, 0.89) | (0.48, 0.86) | ||
Ethnicity (Non-White) | White | 1.72 | 0.86 | 0.75 | 0.47 | 0.49 |
(1.60, 1.85) | (0.70, 1.02) | (0.42, 1.08) | (0.16, 0.79) | (0.26, 0.71) | ||
Ethnicity (Missing) | 0.93 | 1.12 | 1.07 | 1.07 | 0.97 | |
(0.86, 1.00) | (1.02, 1.22) | (0.89, 1.26) | (0.92, 1.22) | (0.85, 1.08) | ||
Marital Status (married) | Single | 1.01 | 1.01 | 0.90 | 1.02 | 0.96 |
(0.97, 1.05) | (0.95, 1.06) | (0.80, 1.01) | (0.94, 1.10) | (0.90, 1.03) | ||
Marital Status (separated) | 0.56 | 1.5 | 1.72 | 1.43 | 1.39 | |
(0.50, 0.63) | (1.42, 1.59) | (1.58, 1.87) | (1.30, 1.55) | (1.30, 1.49) | ||
Marital Status (divorced) | 0.71 | 1.31 | 1.28 | 1.22 | 1.23 | |
(0.67, 0.76) | (1.24, 1.37) | (1.16, 1.40) | (1.12, 1.32) | (1.15, 1.30) | ||
Marital Status (widowed) | 0.98 | 1.03 | 1.07 | 0.98 | 0.99 | |
(0.92, 1.04) | (0.95, 1.11) | (0.92, 1.21) | (0.85, 1.10) | (0.90, 1.07) | ||
Living Alone | Not living alone | 0.87 | 0.99 | 1.18 | 1.10 | 1.28 |
(0.83, 0.91) | (0.94, 1.04) | (1.09, 1.28) | (1.02, 1.18) | (1.22, 1.34) | ||
Social Grade (II) | Grade I | 0.78 | 1.24 | 1.14 | 1.22 | 1.26 |
(Professional) | (0.74, 0.82) | (1.19, 1.30) | (1.03, 1.25) | (1.13, 1.30) | (1.19, 1.33) | |
Social Grade (III) | 0.75 | 1.33 | 1.16 | 1.17 | 1.32 | |
(0.71, 0.79) | (1.27, 1.39) | (1.04, 1.28) | (1.08, 1.26) | (1.25, 1.40) | ||
Social Grade (IV) | 0.66 | 1.41 | 1.26 | 1.37 | 1.48 | |
(0.61, 0.70) | (1.35, 1.47) | (1.15, 1.38) | (1.27, 1.46) | (1.41, 1.55) | ||
Social Grade (V) | 0.59 | 1.31 | 1.35 | 1.36 | 1.69 | |
(0.52, 0.66) | (1.22, 1.41) | (1.19, 1.51) | (1.23, 1.50) | (1.59, 1.78) | ||
Employment (Retired) | Employed | 0.65 | 1.1 | 1.51 | 1.23 | 1.96 |
(0.60, 0.70) | (1.02, 1.17) | (1.38, 1.64) | (1.12, 1.35) | (1.89, 2.03) | ||
Employment (Out of labour force) | 0.34 (0.31, 0.38) | 1.25 (1.19, 1.30) | 2.23 (2.14, 2.32) | 1.75 (1.67, 1.82) | 4.06 (4.01, 4.11) | |
Employment (Unemployed) | 0.53 | 1.73 | 2.09 | 1.54 | 1.42 | |
(0.46, 0.60) | (1.64, 1.82) | (1.93, 2.24) | (1.40, 1.67) | (1.30, 1.54) | ||
Carstairs (decile 2) | Decile 1 | 0.93 | 1.06 | 1.08 | 1.02 | 1.09 |
(Affluent) | (0.87, 0.99) | (0.98, 1.14) | (0.92, 1.24) | (0.90, 1.15) | (0.99, 1.18) | |
Carstairs (decile 3) | 0.90 | 1.06 | 1.00 | 1.10 | 1.19 | |
(0.84, 0.96) | (0.98, 1.14) | (0.84, 1.16) | (0.97, 1.22) | (1.09, 1.28) | ||
Carstairs (decile 4) | 0.80 | 1.16 | 1.32 | 1.13 | 1.27 | |
(0.74, 0.86) | (1.08, 1.24) | (1.17, 1.48) | (1.01, 1.25) | (1.18, 1.37) | ||
Carstairs (decile 5) | 0.80 | 1.15 | 1.26 | 1.22 | 1.27 | |
(0.74, 0.86) | (1.07, 1.23) | (1.11, 1.42) | (1.09, 1.34) | (1.17, 1.36) | ||
Carstairs (decile 6) | 0.74 | 1.27 | 1.31 | 1.1 | 1.44 | |
(0.68, 0.79) | (1.19, 1.35) | (1.16, 1.47) | (0.97, 1.23) | (1.34, 1.53) | ||
Carstairs (decile 7) | 0.70 | 1.25 | 1.34 | 1.34 | 1.50 | |
(0.64, 0.75) | (1.17, 1.33) | (1.18, 1.49) | (1.22, 1.47) | (1.41, 1.60) | ||
Carstairs (decile 8) | 0.64 | 1.37 | 1.44 | 1.30 | 1.59 | |
(0.59, 0.70) | (1.29, 1.45) | (1.29, 1.59) | (1.18, 1.42) | (1.50, 1.68) | ||
Carstairs (decile 9) | 0.61 | 1.40 | 1.37 | 1.35 | 1.72 | |
(0.55, 0.67) | (1.32, 1.48) | (1.21, 1.52) | (1.22, 1.47) | (1.62, 1.81) | ||
Carstairs (decile 10) | 0.54 | 1.54 | 1.54 | 1.52 | 1.74 | |
(0.48, 0.60) | (1.46, 1.63) | (1.38, 1.70) | (1.40, 1.65) | (1.64, 1.83) |